LymeNet Flash: Serotonin Syndrome

LymeNet on Facebook

LymeNet on Twitter

Follow @LymeDiseaseNet

The Lyme Disease Network receives a commission from Amazon.com for each purchase originating from this site.

When purchasing from Amazon.com, please
click here first.

Thank you.

Dedicated to the Bachmann Family

LymeNet needs your help:
LymeNet 2020 fund drive

The Lyme Disease Network is a non-profit organization funded by individual donations.

»	LymeNet Flash » Questions and Discussion » Medical Questions » Serotonin Syndrome

UBBFriend: Email this page to someone!

Author

Topic: Serotonin Syndrome

linky123
Frequent Contributor (1K+ posts)
Member # 19974

posted

Has anyone had Serotonin Syndrome? If so how did you get rid of it?

I recently developed severe burning skin, high blood pressure, heart palpitations and my pupils were dilated. I went to the ER and was given an IV with lorazepam. It worked great, the skin burning went away and I felt so much better. After several days I has started to come back, even after I have stopped all meds.

This morning the Dr. gave me Periactin (cyproheptadine) which is supposed to help reduce Serotin. So far it has not helped.

Does anyone have any ideas?

--------------------
'Come to me, all you who are weary and burdened, and I will give you rest.' Matthew 11:28

Posts: 2607 | From Hooterville | Registered: Apr 2009 | IP: Logged |

Lymetoo
Moderator
Member # 743

posted

Perhaps you are getting some answers now?? Have they identified which drug is causing it?

Here is info on treatments:

http://www.webmd.com/depression/guide/serotonin-syndrome-causes-symptoms-treatments?page=2#3

--------------------
--Lymetutu--
Opinions, not medical advice!

Posts: 96222 | From Texas | Registered: Feb 2001 | IP: Logged |

Jordana
Frequent Contributor (1K+ posts)
Member # 45305

posted

Periactin should help but you should ask the doc for more lorazepam.

What did your serotonin syndrome feel like?

I think a person can get serotonin syndrome from antibiotics. I've never read that's true but I'm sure of it. When you're taking abx and you have gut issues the gut can start just pumping out a ton of serotonin. I think this happened to me when I was trying to treat myself.

Posts: 2057 | From Florida | Registered: Feb 2015 | IP: Logged |

Marnie
Frequent Contributor (5K+ posts)
Member # 773

posted

MAO-A is needed to breakdown serotonin. With (genetically) low MAO-A = excess serotonin (and dopamine and norepinephrine).

Some persons can't handle SSRIs for depression because they have too little MAO-A and this -> excessive serotonin.

B2, riboflavin is needed to make MAO-A.

It works in synergy with P5P (active B6), Mg and Ca in a supplement by Now (brand) called P5P. One taken per day in the morning should help.

Remember years ago, a drug called Bendectin was used for the typical N/V of pregnancy (excess serotonin)...well, it was Pyridoxine/doxylamine.

For hyperemesis during pregnancy, sometimes docs use Zofran.

Bendectin:

Pyridoxine is one form of B6.

Doxylamine succinate is in Unisom sleep tabs.

Here's the history of Bendectin - which is back on the market and been renamed (and is now timed release):

http://webcache.googleusercontent.com/search?q=cache:pB2PZuloPAQJ:http://www.bendectin.com/

There is a complex interaction between substance P (neurokinin-1 )receptors and serotonin and norepinephrine.

Here is a link to the symptoms and some causes of serotonin syndrome:

http://www.webmd.com/depression/guide/serotonin-syndrome-causes-symptoms-treatments

Posts: 9424 | From Sunshine State | Registered: Mar 2001 | IP: Logged |

Printer-friendly view of this topic

The Lyme Disease Network is a non-profit organization funded by individual donations. If you would like to support the Network and the LymeNet system of Web services, please send your donations to:

The Lyme Disease Network of New Jersey
907 Pebble Creek Court, Pennington, NJ 08534 USA
http://www.lymenet.org/