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» LymeNet Flash » Questions and Discussion » Medical Questions » Anti immuno confusio

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Author Topic: Anti immuno confusio
LymeInCoconut
Junior Member
Member # 47104

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Hello all: I have an acquaintance who has presented with the following lab results:

Positive ANA and hi rheumatoid factor, plus

immunoglobulin E, Total 117 Range 0-100

Antiextractable Nuclear Ag RNP Antibodies 1.4 Range 0-.9

The doc says something about lupus being a possibiloty...but we know how those things go. And no one ever asks "Why?"

Anyway,more info needed, BUT, can anyone here help to shed some light on this - as in, what are the odds that Lyme should or would fit into this picture? What would be the next action to take / tests to order, so that this person may get closer to the truth, whatever it may be? (As in, avoiding junk diagnoses, and endless tail-chasing, and dead end streets.)

Thank you all for your kindness and consideration.

Cheers, Dave

Posts: 6 | From St. Louis, MO | Registered: Dec 2015  |  IP: Logged | Report this post to a Moderator
WPinVA
Frequent Contributor (1K+ posts)
Member # 33581

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I have a positive ANA too and my allergist wanted me to go to a rheumotologist. My LLMD said no, it's due to the Lyme.

so you could suggest Lyme testing - I'd start with a Western Blot (NOT an ELISA) through Lab Corp. If that doesn't work, Igenex.

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Jordana
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Lupus is always a possibility, even when there's no positive ANA.

If there is no other specific antibody being made except for anti-RNP then it's really a catchall "autoimmune" issue with no specificity for anything.

IgE can start to ramp up with parasites.

So, yup; Labcorp, then Igenex.

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Keebler
Honored Contributor (25K+ posts)
Member # 12673

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Lyme is very often the CAUSE of lupus. With lyme, the immune system flips in some unusual ways that most doctors are not aware of.
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Posts: 48021 | From Tree House | Registered: Jul 2007  |  IP: Logged | Report this post to a Moderator
   

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