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» LymeNet Flash » Questions and Discussion » Medical Questions » how much milk thistle?

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Author Topic: how much milk thistle?
randibear
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I've got a bottle of 175. I need the liver support.

it says one per day? is that enough?

--------------------
do not look back when the only course is forward

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momintexas
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Mine is 175mg and I take it once a day.
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Keebler
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It's good to start just one a day for a week or so to see how you do with it (if it's too strong, Dandelion might work better), however, I really think it's best 3 x day, after all, we eat 3 x day so that nutrients are evenly distributed to our body's cells.

This is food for the liver and once a day is just not nearly enough unless maybe there is other liver support also on board.


http://oneearthherbs.squarespace.com/important-herbs/milk-thistle-seed-silybum-marianum.html

From THE ONE EARTH HERBAL SOURCE BOOK

MILK THISTLE SEED (Silybum marianum)

Excerpt:

Starting dosage:

• Concentrated standardized silymarin capsules (70-210 mg):

one to two pills, two to three times per day

• 1:5 Tincture: 20-40 drops three times per day

Much more detail here . . . also be aware to keep it away from Rx by a couple of hours. Why? That's all explained in this chapter.
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Keebler
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http://www.naturalnews.com/milk_thistle.html

Milk Thistle - 16 articles from NATURAL NEWS.

Oh, be sure to get an excellent brand of top quality. Some (especially in big box stores or vitamin stores) are not at all what they are supposed to be.
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2Cranes
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Hi Randi,

I dont know you or your protocol, maybe you know this, but they are finding more and more that milk thistle should not be taken with many drugs and even herbs. And some medical conditions are made worse by milkthiste.

I think we all know not to take it if you are taking mepron or malarone.

But it also decrease the effectiveness of allergy drugs, cholesterol-lowering drugs, anti-anxiety drugs, anti-platelet and anticoagulant drugs, sedatives, sleeping medications and certain cancer and anitviral drugs.

It decreases drug/herb bioavailability in any chemical that goes through a certain liver enzyme pathway (P450 3A4 (CYP3A4), anywhere from 50 to 100 percent). This is a heavily used enzyme pathway in your liver, and that is why it affects so many things

And on the flip side, it can also increase the levels of other compounds. A good example of this is it can increase certain sex hormones your body makes. And thats why women with a history of endometriosis, uterine fibroids, history of breast/uterine cancers, and prostrate cancer, should avoid this herb.

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Keebler
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It is important to consider interaction, timing, choice of specific herb or nutrient such as NAC that is also top liver support.

Still . . . Milk thistle - and other liver support - can be included in a protocol that treats babesia, it's just that the timing of ANY liver or kidney support herbs requires some thought.

And, as mentioned above, check with all Rx you may be taking with the addition of ANYTHING.

It's important to read - oh, probably at least a dozen articles from those educated in the field (naturopathic doctors or similar) on anything you take, I think, so that a wide range of aspects can be considered. Most MDs do not have any training in this area. But a few have done well.

You might consult the LLMDs who have written about milk thistle and other herbal liver supports, of course. Dr. H, Dr. S., Dr. L . . . and also read all you can from Harrod Buhner.

Dr. B's guidelines discuss the importance of certain liver supports, too.

Milk Thistle may not be the best choice for everyone, but some kind of specific nutrient dense liver / kidney support is absolutely vital.

The thing is that the liver must have support for those with chronic infection that not only increases toxic load but also can damage the liver.

There are ways to work with it that do not interfere with Rx such as the timing, the kind (there are so many herbs that are helpful to the liver).

If liver support is neglected, damage to the liver, to the eyes, to the ears, and even the brain can occur in presence of a such a toxic infection as lyme.

If you have access to a good LL ND, that is best, of course so they can guide you with a variety of methods. More detail here:

http://flash.lymenet.org/scripts/ultimatebb.cgi?ubb=get_topic;f=3;t=030792;p=0

LIVER & KIDNEY SUPPORT & and several HERXHEIMER support links, too.

As for information on what can help the Cytochrome P-450 liver detox pathway, milk thistle can help it, actually. And in the Porphyria thread inside this set, there are others more specific to this function.

As for interaction with so many of the drugs that are so common for everyone these days, often, when the liver is supported, the need for many other [I'll call them non-essential, symptom relief geared] Rx methods can decrease. When the liver works better, the body works better.
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[ 03-13-2016, 08:58 PM: Message edited by: Keebler ]

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Keebler
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Some LLMDs who have addressed liver support:

website & book: http://www.cangetbetter.com/

by Dr. H, a leading ILADS LLMD - November 2013

- Why Can't I Get Better?: Solving the Mystery of Lyme and Chronic Disease


http://www.lymedoctor.com/

The Lyme Disease Solution - By Dr. S.

Another excellent and well respected LLMD, book, website

First book is very good - yet a new 2016 protocol book is due soon from this author, too.


This book may as I do know the past work of this doctor has included such, I've just not yet read the new book:

http://whatislyme.com/coming-soon-new-lyme-disease-book-by-kenneth-b-liegner-m-d/

a new book release - scroll down here for more detail about the author

THE CRUCIBLE OF CHRONIC LYME DISEASE - By Dr. K.L. - Nov. 2015
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Keebler
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From one of the most well respected herbal researchers in the world at ITM:

http://www.itmonline.org/arts/herbdrug.htm

THE INTERACTIONS OF HERBS AND DRUGS

Institute for Traditional Medicine, Portland, Oregon

This article will also help guide methods for cross searching drugs that are new to the market.
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Keebler
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http://oneearthherbs.squarespace.com/actions-interactions

From THE ONE EARTH HERBAL SOURCEBOOK

Guidelines for THE SAFE USE OF HERBS
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Keebler
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Just stumbled upon this in my file notes:

http://www.ted.com/talks/russ_altman_what_really_happens_when_you_mix_medications

TED*MED Nov. 2015: What Really Happens When You Mix Medications?

Russ Altman - 14:45 Video . . . and transcript

If you take two different medications for two different reasons, here's a sobering thought:

your doctor may not fully understand what happens when they're combined, because drug interactions are incredibly hard to study.

In this fascinating and accessible talk, Russ Altman shows how doctors are studying unexpected drug interactions using a surprising resource: search engine queries.
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