I had the MTHFR test done and found I'm heterozygous for the mutation. Thus on paper my enzyme pathway would be operating at ~50% in theory.
I had a methylation test done and found out I am indeed under methylating. My doc recommended sam-e, methyl folate and a form of b-6.
Has anyone else tried this? I have suffered from chronic low grade depression my whole life so the Sam-e supplement sounds promising. I went off my antidepressants so I'm able to do a high dose of Sam-e and it has helped my mood a bit. I know you need to be careful taking Sam-e and SSRIs due to serotonin sickness.
But I haven't head much about sam-e here and it might be useful for some Lyme sufferors and those with mild to moderate depression that aren't being treated with antidepressants.
Anyone try it?
The price if Sam-e is a little outrageous though!
Posts: 133 | From North Shore | Registered: Sep 2015
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MichaelTampa
Frequent Contributor (1K+ posts)
Member # 24868
posted
I took it some years back, before I started getting some decent lyme treatment (before I was diagnosed with lyme). I felt it was pretty good.
Posts: 1927 | From se usa | Registered: Mar 2010
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Rumigirl
Frequent Contributor (1K+ posts)
Member # 15091
posted
I've taken it for years; it is good.
Now brand, or Life Extension, has cheaper prices. I think Now is cheaper. It's still not cheap, but relatively cheaper.
You can also take TMG, which is cheap, which is supposed to turn into Sam-e. I do both. That way, you can get away with a little less Sam-e.
Watch out for getting too hyper if you take too much of either, though.
Posts: 3771 | From around | Registered: Mar 2008
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bluelyme
Frequent Contributor (1K+ posts)
Member # 47170
posted
Ya helped depression but anxiety was up ...like a person with out arms i just couldnt hang ...
-------------------- Blue Posts: 1539 | From southwest | Registered: Dec 2015
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