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» LymeNet Flash » Questions and Discussion » Medical Questions » Manganese Deficiency and MCS connection??

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Author Topic: Manganese Deficiency and MCS connection??
Lymetoo
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Someone on another board said that MCS (multiple chemical sensitivity) is associated with manganese deficiency.

I have never heard that and have no idea if it is true, but we do know that Lyme disease depletes our manganese.

Here is proof in case you didn't see that one awhile back:

http://www.huffingtonpost.com/2013/03/24/lyme-disease-bacteria-immune-system-iron_n_2934134.html

So, can we just supplement manganese?

--------------------
--Lymetutu--
Opinions, not medical advice!

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aklnwlf
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Really interesting read!

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Do not take this as medical advice. This comment is based on opinion and personal experience only.

Alaska Lone Wolf

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Christopher J
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I would absolutely NOT supplement Manganese. That is the worst possible thing you can do because the Lyme will grow out of control. Lyme needs manganese, and infact it needs a lot of manganese.

You might remember that study where the reason Claritin worked is because it reduced Manganese in the system.

From personal experience, once I removed al foods high in manganese from my diet, I started making more and more gains in overall health.

You can weaken it dramatically by cutting off its supply which then makes it more susceptible to antibiotic treatment.

(breaking up the post for easier reading for many here)

[ 12-05-2016, 05:08 AM: Message edited by: Robin123 ]

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AJB
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That is really interesting about the Claritin~anyone take it daily to assist w/ treatment?
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Christopher J
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I did for a while, but you cant take high enough doses of Claritin to achieve that result. What I really took away from that is to cut off manganese in my diet because it was something tangible I could do. Very similar in a way to the iron depletion diet for Malaria.
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Catgirl
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Fascinating Lymetoo if that's the case (MCS and manganese deficiency). I've been limiting manganese for a while.

Good stuff Christoper!

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--Keep an open mind about everything. Also, remember to visit ACTIVISM (we can change things together).

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lookup
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"Dr. K has found a high correlation between patients with chronic Lyme disease and those with Kryptopyrroluria (KPU), or more precisely Hemopyrrollactamuria (HPU).

The condition is alternatively known as the "Mauve Factor....
HPLs bind to zinc, biotin, manganese, vitamin B6, arachidonic acid and other important compounds and lead to a significant depletion of these substances in the body."

http://www.publichealthalert.org/kpuhpu-a-major-piece-of-the-puzzle-in-overcoming-chronic-lyme-disease.html

I wonder if/how MCS and KPU/HPU are related?

**editing out doctor's name**

[ 12-04-2016, 04:46 PM: Message edited by: Robin123 ]

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Jordana
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Manganese is kind of dangerous. No one really knows what it does for sure and it's not a necessary part of the diet in the trace amounts we ingest.

A high manganese diet was connected to prion diseases in cattle so that was enough for me not to supplement it.

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Lymetoo
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I would not suggest decreasing manganese in the diet myself. Living with MCS is not fun .. not in the least.

My battle is no longer the lyme, it's the MCAS and the resulting MCS.

I've wondered many times about the HPU/KPU but I don't seem to have the symptoms of it.

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--Lymetutu--
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Jordana
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I think MCAS is still a response to a latent infection of some kind. This paper has a list of histamine antagonists they're using in research.

https://www.biotrend.com/download/BTReview_Jan2010_Mastcell.pdf

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Lymetoo
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It's the chicken and egg thing. Some of us know this has been in our genetics for many generations.

I think it's there, and then it's kicked off by something. For me, it was ramped up by a stressful event several years ago.

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--Lymetutu--
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lapis29
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what does a manganese free diet look like?

am very interested, anyone know about this?

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Lymetoo
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Why would you want to limit it?

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--Lymetutu--
Opinions, not medical advice!

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lapis29
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well theoretically if you starve your body of manganese, you also starve BB of it at the same time.

however, multiple places say bb will ultimately be fine and find the manganese it needs one way or another, so maybe it wont work.

at least one doctor is using a Mang. chelating agent called para-aminosalicylic acid to treat Lyme, it also happens to be an antibiotic

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http://www.bayarealyme.org/blog/alternative-treatments-for-lyme-disease/

“A second tier anti-tuberculosis drug called para-aminosalicylic acid (PAS) can bring down manganese levels in the human body and make life very tough for the Lyme bacteria, but there have been no clinical studies in this area, and PAS is not for everyone. (Borrelia will feel the effects of manganese deficiency long before humans, as humans are no

“My anecdotal experience with PAS is that, at 2/3 the dose recommended for treating tuberculosis, it takes about two weeks to bring down manganese levels enough for the organism to start to suffer and for patients to feel a deeper level of relief. I have had no one report that 10 mg of loratadine was doing anything for them one way or another. That doesn’t mean it won’t or can’t but, again… what is the correct dose, and if the correct dose for doing this is well beyond the normal dose then there will there be untoward reactions to taking so much loratadine? The problem is no one knows yet.

“I have used PAS for a couple of years now, but not just with Lyme. I have used it in patients who exhibit Parkinsonism, because for many there is manganese-toxicity in the parts of the brain that deal with dopamine. I have seen it work many times, so I know it is bringing down manganese levels. Using PAS at a fraction of the dose used to treat TB also makes me feel comfortable using it off-label.

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Lymetoo
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quote:
Originally posted by Lymetoo:
Someone on another board said that MCS (multiple chemical sensitivity) is associated with manganese deficiency.

I have never heard that and have no idea if it is true, but we do know that Lyme disease depletes our manganese.

Here is proof in case you didn't see that one awhile back:

http://www.huffingtonpost.com/2013/03/24/lyme-disease-bacteria-immune-system-iron_n_2934134.html


trust me .. you do not want to add MCS to your list of woes

--------------------
--Lymetutu--
Opinions, not medical advice!

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Lymetoo
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quote:
Originally posted by lapis29:

[QB]

at least one doctor is using a Mang. chelating agent called para-aminosalicylic acid to treat Lyme, it also happens to be an antibiotic




--------------------
--Lymetutu--
Opinions, not medical advice!

Posts: 96222 | From Texas | Registered: Feb 2001  |  IP: Logged | Report this post to a Moderator
   

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