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» LymeNet Flash » Questions and Discussion » Medical Questions » 2025 New Therapeutic Target

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Author Topic: 2025 New Therapeutic Target
Marnie
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“Researchers Identify New Therapeutic Target For Lyme Disease”

The target is LDH…. More specifically LDHA (alpha chain).

“Berberine inhibits LDHA”. Lactic acid dehydrogenase which I explained recently in another post - how Bb uses this enzyme.

WARNING

Dihydroberberine is highly bioavailable. Dihydro = 2 hydrogens.

The green capsules with a 4.6 rating on Amazon suggested dose is 4 capsules.

Be prepared to blow away family members due to excessive flatus. Not joking. I did not have this happen with “regular” Berberine - even doses of Up to 1500mg.

My suggestion if you chose to try this ***with your doctor’s okay, *** is to start with lower doses before dinner and TAKE PROBIOTICS and yougart/kefir also at the same time.

The sustained release ones have a significantly lower rating and more side effects reported by customers.

BTW

HBOT also is known to lower LDHA according to AI when I typed in “HBOT LDHA”
Posts: 9481 | From Sunshine State | Registered: Mar 2001  |  IP: Logged | Report this post to a Moderator
kgg
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Interesting. I have read many accounts of regular Berberine causing gi upset. But that Bihydroberberine was much better tolerated.

Our population has a lot of metabolic disease. This supplement is great for blood sugar control. Equal to Metformin from what I have read.
Posts: 1845 | From Maine | Registered: Jun 2004  |  IP: Logged | Report this post to a Moderator
   

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