I was just wondering because after my flu symptoms subsided, some 3 weeks out after a tick bit that had yielded a large "atypical" rash I felt great, until I upped my doxy to 300mgs. Four days later I was in the Er with a "TIA" . Only whatevr it was , it is now clear it wasn't a TIA. :ater I read on these boards about herxes and assumed that's what I had experienced.

My question to you all is: is it within the realm of possibility that a healthy (uninfected,) person take a large dose of abx and have a severe reaction to the meds themselves.? My GP (before I found a lld) had hypothezised this,but also mentioned the possibility of a herx. (good for him!)

Consider two effects of the doxy.

1. Increased pressure in the brain(intracranial pressure). The sensation of pulsing may be the tip-off to this.
2. Severe Jarisch-Herxheimer reaction

I've had both, severely, when doing doxycycline. First time infected, with a loading dose of, I think, 200mg.

A few "moons-ago," I did either 100mg or 200mg,and same thing. This can be very dangerous. So I skipped next dose, and 2-3 days before taking the next 100mg. As I recall,from then on, I increased the time interval(12-24hr.) between doses,to minimize negative effects.

dq