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» LymeNet Flash » Questions and Discussion » Medical Questions » inflamation tests with lyme? need info

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Author Topic: inflamation tests with lyme? need info
caat
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has anyone had inflamation tests? I just had "C reactive protien" and ESR blood tests done. The results of those may have a big influence on my treatment so it's important for me to know.

Does a lyme infection show results on these very general blood tests? They show general inflamtion in the body. I do have arthritis symptoms and occasional heart irregularities.

I'm sure they would be sky high for a staph infection or bartonella, but what about lyme?


Posts: 1436 | From Humboldt county ca usa | Registered: Mar 2002  |  IP: Logged | Report this post to a Moderator
caat
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Oops- nevermind.

I was spelling protein wrong in the search engine- I found it. Yep, lyme can increase results of both tests.


Posts: 1436 | From Humboldt county ca usa | Registered: Mar 2002  |  IP: Logged | Report this post to a Moderator
riversinger
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caat,

Lyme CAN increase levels on both these tests, but it doesn't always.

My CRP, sed rate, rheumatoid factor, ANA, homocysteine, and just about everything else they use to measure inflamation have always been normal. This is even though I have easily identifiable, even palpable inflamation.

The only things that have ever shown anything are thyroid antibodies, ASO (antistreptolysin), and recently an elevated 1,25-D level.


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JillF
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My sed rate was at 40 but now is at 35, which is pretty normal for a woman (from what I've been told).

My CRP rate started at 32.3. Normal is 0-4.9. Right now, my CRP rate is 95.


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caat
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Thanks!

Well, that's not very encouraging... Might as well flip a coin. Have either of you had any (reliable??) tests that measure the immune system?


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riversinger
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caat,

There are lots of tests used to measure immune function. Many of them are expensive, and have to be sent to special labs. It all depends on what you are trying to look for.

Many of the ones I mentioned are first line tests when people present with pain and inflammation and fatigue. After that it gets more focused as to just what is going on.

Some labs do immune panels for people that have CFS like symptoms. But often many of these tests come back normal.

Of course antibody tests, like the western blot, also measure the immune system, but only whether it is reacting to an antigen.


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caat
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Thanks Riversinger! Oh, I know you Just wrote with you and Cave. I have no idea what I'm looking for as regards tests for the immune system.

But to be honest I really don't want to climb the learning curve with the language and theory of those tests at the chemical molecular level- the way that stuff interacts is way over my head... too mathmatical. I'll wait & see- maybe the coin will land "heads" up. If not, I'll be persistant anyways, don't worry

I'll save this too, I looked over the WB I had again & it seems at least one of the strains I have is a california strain. So your pos tests would be a good bet if needed.


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MarieElaine
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You might want to check out this group:

Yahoo! Groups : marshallprotocol

The blood tests run measure the level of inflammation by a ratio.

Marie


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imagine2
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caat,
My C-reactive protein was normal but my MMP9 was "off the charts". MMP9 is the "most efficient deliverer of inflammation in the body." See if your doctor will test for this. Esoterix is the lab that does this testing. If you go to Labcorp they will send it to Esoterix.

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caat
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thanks everyone

I guess immune sys. tests are out. I'll check out MMP9.


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hesfoot
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Hi,

What did your ESR show? A research scientist on the Marshall Protocol list wrote this about ESR, suggests that the ESR falls when an intracellular infection becomes severe:

"The absolute value of the sed rate is less important to me than the observation of a very high 1,25-D (or sIL2R) in conjunction with a low sed rate... The way that I see the autoimmune diseases progress is that a series of infections accumulate throughout life. At some point one or more of the species which have perfectly adapted to intracellular living infect the patient. At this point the Th1 cytokine cascade strengthens to the point which makes it possible for L-forms of some of the other less aggressive pathogens to also enter immune cell cytoplasms. At this point the immune system can no longer kill any more bacteria and so the ESR falls. There are now very few antibody/pathogen complexes in the blood stream."

hesfoot


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lifewithlyme
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hey caat,
just wanted to let you know - my c-reactive was really high; my dr. was concerned. after three months on biaxin/ceftin, it went down so much it was negligible. don't lose hope!
sarah

Posts: 588 | From Wallingford, CT USA | Registered: Sep 2003  |  IP: Logged | Report this post to a Moderator
   

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