posted
I am on zithromax, Mepron and just started Flagyl. Does anyone know if it would be too much to add Artemisinin to the mix.
Also is 250 mg of flagyl every 6 hours a normal dose? Thanks for any info.
Posts: 104 | From Thornton Pa. USA | Registered: Jul 2003
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once bitten
Unregistered
posted
good combo. adding the artemesia and then artemisinin from Allergy Research finally got rid of the gd babesia. I was on the mep zith combo for over two and a half years. adding the art did it for me and I had a real stubborn case. I might add it in after a while tho so the onslaught isnt too much for you.
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posted
I also found artimesia/artimisinin to be very powerful against babesia- I took it along with many combis, including 'malerone'/'biaxin'/doxy and tinidazole/'biaxin' and had no interaction problems (just the normal "adjustment reactions" and "herxes", which got better after a while. I started with a lower dose and increased (as LLMD recommended). Also I alternated extract (artimisinin) with the raw herb, sometimes taking one of each. (This was my own experiment, and it seemed to be the way to go for me; I had good results. I used the "allergy research" brand, also. DaveS
Posts: 4567 | From ithaca, NY, usa | Registered: Nov 2000
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WildCondor
Unregistered
posted
Good stuff! I took Mepron/Zithromax/artemesia and it kicks butt! Make sure its for atleast 4 months and to check your blood regularly.
posted
I've been taking Artemisinin for several months now with different combinations (first Ceftin/malarone, then Ceftin/malarone, Zitromax and now Ceftin/Zithromax/Plaquenil_.
My doc seems to think that Artemisinin is better than Artemisia. I'm not sure about the recommended dose. The doc had me build up. I take 3, 100 mg tablets per day.
He recommended Nutricology brand. I bought directly from them until someone pointed me to organic pharmacy where it was 1/2 the price. I called Nutricology to make sure it wasn't a scam and it's not. They said Organic Pharmacy buys it in large lots so they get a big discount. Here is their website: http://www.organic-pharmacy.com/ARG.Artemisinin.htm
[This message has been edited by gopats (edited 24 July 2004).]
quote:Originally posted by Murt1: Also is 250 mg of flagyl every 6 hours a normal dose? Thanks for any info.
The dosing schedule for Flagyl is usually 2x or 3x a day instead of 4x. (Flagyl half life is 8 hours and with Flagyl and Lyme Disease, you are typically trying to hit a _level_ of drug in your body, not _duration_)
mg/kg dosing info (for malaria) for artemsinin can be found easily through Google. I personally did 900mg a day of Allergy Research for 10 days.
arg82
Frequent Contributor (1K+ posts)
Member # 161
posted
I'm doing Mepron, Zithro, and Artemisinin now (been on it for the past two and a half months). I'm also on the Allergy Research Group brand Artemisinin and my dosage is 2 100mg capsules three times a day for a total of 600mg a day. I think it's making a difference, but it's unclear if I really had lingering Babesia or not.
--Annie
------------------ ``The best way out is always through.'' -Robert Frost
Posts: 2184 | From Rochester, MA | Registered: Oct 2000
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TheCrimeOfLyme
Frequent Contributor (1K+ posts)
Member # 4019
posted
Glad to see others have taken advantage of the organic pharmacy I posted.
Its ridiculous to pay so much for that , when you can get it for 17.00.
How ya doing Murt?
Posts: 3169 | From Greensburg, Pennsylvania | Registered: Jun 2003
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minoucat
Frequent Contributor (1K+ posts)
Member # 5175
posted
I have not seen any contraindications for taking artemesinin with other drugs, but that may be as much due to lack of research as anything. There does seem to be excellent documentation on artemisinin alone for malaria and cancer in particular.
Flagyl is hard on the liver and can cause a major change in liver enzymes and lead to liver damage. This is mostly considered to be reversible if caught in time, according to my reading. Ultimately, all long term abx are hard on the liver, but flagyl seems to be of special concern.
My doc and ND both have concerns about the long-term effects of artemesinin on the liver, and recommend taking a break from it at least every 5 months, staying off it for at least a month, and doing a liver cleanse before restarting.
We're on 300 mg artemesinin, also nutricology brand, 2 x a day (600 mg total), along with mepron, zithromax, and bicillin. Absolutely no problems so far. Have done a couple of very short (one 6 day and one 4 day } abx breaks and liver cleanses in the past 4 months. If you buy in bulk (4 bottles or more) you can often get great deals online -- I think I got my last batch from outletnutrition.com, and it was 14.50 a bottle for Nutricology brand.
So I think WildCondor is right -- be sure to watch your liver enzymes and go for it. We herxed significantly on artemisinin, so start slow.
[This message has been edited by minoucat (edited 01 August 2004).]
A review of existing studies of anti-malarial compound artemisinin recently concluded that adding the Chinese folk remedy for malaria to existing anti-malarial drugs increased the effectiveness of those drugs in fighting malaria.
The International Artemisinin Study Group looked at 16 clinical trials involving 6,000 patients who were administered artemisinin along with other anti-malarial drugs. Artemisinin is an extract from sweet wormwood has been used for centuries in Asia to treat malaria.
Their review found that adding artemisinin to existing compounds doubled the rate of parasite clearance (the level of parasites removed from the blood) with no additional side effects. Additionally, patients taking artemisinin combination therapies were less likely to suffer a relapse of the disease after ending treatment.
In an article in Lancet describing the results of the survey, the International Artemisinin Study Group wrote,
If used widely, this inexpensive, fixed-dose artemisinin-based combination antimalarial could make important contributions to 'rolling back malaria'.
Sources:
Drug cocktail 'may beat malaria'. The BBC, January 2, 2004.
Drug combinations for malaria: time to ACT?. The Lancet, January 3, 2004.
Combination therapy, the best way to tackle malaria: Lancet. January 2, 2004.
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