I've read that Doxy 400-1000mg is a likely candidate. Does 400 mg really work? Less than that won't? Other ideas?

Ppl here have been on so many different drugs. I understand Lyme is a complex, unknown entity and that everyone is unique, may have co-infections, etc.

I started with arthritic and then moved to neuro symptoms. Now have some cognitive signs showing up. I've spent 6 months not getting answers from my regular drs who took my negative Lyme tests as definitive answers (I was on an antibiotic at the time of my WB which I found out later interferes w/the test). I don't want to waste any more time by spending a month a month on ineffective abx.

Then there is the coinfection thing....

I did well on doxy. I weigh 145 lbs and my llmd had me on 600mg a day. Nice solid herxing goin on with that.

I did have babesia , so i got the mepron and zith combo. It was the best for me..made lots of progress.

make sure you spend some time on flagyl to get the cyst form, along with another abx to get the regular form.

most folks change the drugs up a few times before its all said and done. there is no holy grail it seems.

I did well with the above drugs, not so well on ceftin , amoxicillin, or biaxin. other people do well on them..

usually takes trial and err.

greg

Please don't torture yourself any more with 'quacks' - those MD's who know nothing about Lyme. I spent 7 months chasing my tail, two negative test by the lab insurance 'approves', only to watch myself slide downhill. Starting with muscular head and neck pain, to dizziness, to seeing spots and floaters, gastro problems, cognitive problems, sciatic pain, etc....

Please see a real LLMD, who will send your blood to a specialist lab like IgeneX, and will treat you based on your symptoms, not test results... because as you may have seen here many times, there are numerous reasons why test results may be negative.

There are 300 strains of Borrelia,three known forms, multiple known coinfections, and countless unknown coinfections.

Each of these things will have an impact on which antibiotic, or combination of antibiotics, will work for you. There isn't any way to know ahead of time how a particular one will affect you.

I know you don't want to waste time, but it really is an experiment finding what works for you. If you see an experienced Lyme doctor, they will make the best educated guess they can, and will have the experience as well to judge the meaning of your response.

If you've had lyme for a long time, you'll likely get a chance to try quite a few in rotation. Most have to change antibiotics as the organisms change and mutate, or because of reactions to the antibiotics themselves.