I have been taking 400 mg of doxy/daily. I was told that when taking this within the first day or so, I would experience some unpleasant reactions "feeling worse before better".

After reading many stories and researching, most people say that they start feeling really bad after the antibiotics are given.

As of today's date, I have never had any symptoms of getting better or worse. I'm exactly the same as the first day I walked into the doctors office. I was a bit concerned when my physician had a puzzled look on his face after telling him I never experienced any abnormal/worse symptoms. He just suggested keep taking them for another 30 days and see what happens. My doctor's advice was more of a guess than an answer.

I'm starting to think that this is not working for me. Maybe higher dosage or another alternative?

Do you have to "get worse" to know if it's working or not?

Any thoughts????? I'm still new to this.

Six weeks is perhaps too soon to throw in the towel. Treatment for lyme takes a huge amount of patience and fortitude. I know I felt as lousy as ever up until about 6 months when I began seeing a slight improvement and then it was sporadic.

That being said, I would hope you have been tested for coinfections. The general consensus is if you have a coinfection you need to treat that first before you will see
improvement with the lyme.

I also wonder if you are seeing a Lyme Literate MD (LLMD) who has had experience treating lyme and the coinfections. Most of us have discovered that this is the key to getting better.

You may find that any day now you will experience the worsening of symptoms which is called a herx. On the other hand, people here have reported that they never have experienced a herx. It is variable from patient to patient.

Hang in there a bit longer...and check out coinfections and be sure you are being treated by an experienced doctor.

I don't know how knowledgable your doctor is. Unfortunately, even the best have to make their best guess as to which med will work in any specific situation. Treating Lyme is not an exact science.

Were you also tested for coinfections? That can have an impact on how quickly you recover. If you haven't read much about Lyme, you might want to start here:

Treepatrol's Newbie Links

There are so many other variables.

I never went back , herxing wise, BEYOND my deathly ill lyme symptoms. It was a gradual improvement upwards. HOwever, I did get stuck for about 5 months

where I was sliding further and further back.