treepatrol
Honored Contributor (10K+ posts)
Member # 4117
posted
Abbreviations: Bb Borrelia burgdorferi Bmp Bacterial membrane protein Fla Flagellin HGE Human granulocytic ehrlichiosis kDa kilodalton = molecular weight Oms Outer membrane-spanning Osp Outer surface proteins p Protein
Band IgG IgM
18 kDa .# p18 flagellin fragment 22 kDa Immunogenic integral membrane lipoproteins. Cross-reactive with other spirochetes/bacteria. Depending on source, may be specific for Bb or cross-reactive. [Coleman]
(((((((((((23-25 kDa @ # @ # OspC. 25 kDa is specific for Bb )))))))))))
28 kDa .# OspD, Oms28. Specific for Bb 30 kDa # OspA substrate binding protein 31 kDa @ @ OspA 34 kDa @ @ OspB. Specific for Bb 37 kDa . . p37, FlaA gene product. Specific for Bb 39 kDa @ # @ # BmpA. Specific for Bb 41 kDa @ # @ # FlaB 45 kDa .# [Flisiak]; appears for HGE [Ravyn] 58 kDa # 66 kDa # p66 Oms66 Hsp outer/integral membrane protein 73 kDa .. .. 83 kDa . . p83 high molecular mass protein. Specific for Bb 93 kDa @ # # an immunodominant protoplasmic cylinder antigen, associated with the flagellum. Specific for Bb
posted
Thank you for the explanation. I will post back if I find a US lab with capabilities to test for other genospecies of borrelia.
Posts: 159 | From CT, USA | Registered: Jan 2005
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Tincup
Honored Contributor (10K+ posts)
Member # 5829
posted
Quick note...
Igenex Western Blots and PCR's are made from several culture mediums and are able to pick up several strains.. not just senso stricto. That is why they are able to catch some of the strains not normally picked up on other tests... like STARI for one.
Perhaps contact them for more detailed info?
Hey cmichaelo..
The clip you pasted... could you post more? I can't get into the yahoo site you posted and would be interested in reading the information.
Journal of Clinical Microbiology, December 1999, p. 4086-4092, Vol. 37, No. 12 "Scored antibody reactivity determined by immunoblotting shows an association between clinical manifestations and presence of Borrelia burgdorferi sensu stricto, B. garinii, B. afzelii, and B. Valaisiana in humans."
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