quote:
Originally posted by Marnie:
Tree...in case you missed this (posted under Trout's original post):Trout, in the article you quoted:
"Tests on similar fibers taken from Bishop's skin and those of several other
patients in the Bay Area show them to be ***tiny tubes of protein.***But how and
why the filaments are formed remains a mystery for now."
From my first link (watch for the tiny tubes of protein):
"1. Pili (fimbriae) (def)
As seen in the previous section, pili enable some organisms to adhere to receptors on target host cells (see Fig. 1)
and thus colonize and resist flushing by the body. Pili are thin, protein tubes originating from the cytoplasmic membrane and are found in virtually all gram-negative bacteria but not in many gram-positive bacteria.
The pilus has a shaft composed of a protein called pilin. At the end of the shaft is the adhesive tip structure having a shape corresponding to that of specific glycoprotein or glycolipid receptors on a host cell (see Fig. 2).
Because both the bacteria and the host cells have a negative charge, pili may enable the bacteria to bind to host cells without initially having to get close enough to be pushed away by electrostatic repulsion.
Once attached to the host cell, the pili can depolymerize and enable adhesions in the bacterial cell wall to make more intamate contact.
Bacteria are constantly losing and reforming pili as they grow in the body and the same bacterium may switch the adhesive tips of the pili in order to adhere to different types of cells and evade immune defenses (see Fig. 3).
Once again...this is nothing new...basic microbiology.
Thanks Marnie.