After a while on rocephin, I noticed a pattern of feeling somewhat better in the a.m., and then back to bad again starting mid afternoon and into the evening.

I did my infusions at night (about 8 pm) and my LLMD thought maybe I 'processed' rocephin quickly and any daily benefits wore off as the day wore on.

I think it's more my natural biorythms, combined with my being pig-headed and working too much. Which I don't recommend!!

I'm off the IV for now, but I still notice a big difference M-F. I'm much more tired and in much more pain later in the day when I work (which makes sense). I sleep a lot on weekends and don't notice as much of a good/morning bad/evening pattern, but it's still there.

It's probably allittle bit of both overdoing it and the meds. I get so stressed out about missing more work. I've been feeling pretty bad since August and have missed a few weeks of work allittle at a time, I think the boss is getting tired of my being out a lot.

Our LLMD said he's never seen anybody cured in Feb. or March. Wasn't sure if it was "keet" cycles or the cold, but I found that interesting.

I used to get very tired right after doing my infusion. My nurse said that she has several people who fall asleep during the infusion. I have seen that happen because she has those patients do the daily infusion in her office, where I had my bandages changed.

But, like you, after a while I started to feel pretty peppy shortly after finishing the infusion, like a second wind. I did the infusions in the evening on my second round of Rocephin because my reaction was sometimes unpredicatble.

I am going to venture an educated guess that the stress you have about your job, income, etc. are causing you to feel like you are herxing. I don't think it is possible to herx daily (by definition of herx). I remember feeling extremely stressed over how I was going to pay my bills and keep my clients. I also stressed because every day was a mystery. Some days I would halucinate, some I was able to jog. I just couldn't predict and couldn't make any plans because of this.

The stress also caused me to panic a few times, like when I would drive to a meeting and suddenly feel like I could not make the 20 mile drive back. I felt alone and scared at times like that.

Eventually, I got used to the Rocephin and told everyone around me exactly what was happening. I did lose a client or 2. I even lost a friend who couldn't deal with my constant cancelling of our plans. But, it was a great load off of me to tell others how stressful this was for me and how unpredicatble it was. I was amazed at how my family, good friend, and many clients rallied and offered support, both emotional and financial.

Try to reduce your stress by accepting that you will feel achy and will sleep lots and will not be able to work at full tilt. There's isn't much you can do about it. You need rest and some peace of mind. Delegate, if you can. I had a colleague help me with my work. She was more than happy when I asked. You will be surprised how people will respond if you give them the chance to help you. It makes them feel good sometimes.

Ok, I'll stop now. Just want you to know you are not experiencing anything unusual.

Thanks again. I forget that I am sicker than I appear.

I wish I didn't have to work so that I could concentrate on getting better 100%, but unfortunately that's not going to happen. I sleep A LOT on the weekends. Usually Friday night I sleep 12 hours and then take a nap Saturday afternoon too. I go to bed early every night because I have to get up at 6 a.m. There are nights I'm in bed by 7 p.m.

You have to do what's good for you working within the parameters you have. And try to keep anxiety and stress to a minimum.

Oh, I did lose my gallbadder after the Rocephin. I really haven't missed it.