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» LymeNet Flash » Questions and Discussion » Medical Questions » Flagyl pins and needles

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Author Topic: Flagyl pins and needles
lymeHerx001
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Does anyone get pins and needles after they take flagyl?

This is the 4th time taking it.

I took some Mondayl night probabbly 1/2 a pill in 2 doses. I felt some herx rections in my knees and body but they didnt last long at all.

Did the same thing last night with the same response.

Today I just took the same dosage and right after I felt pins and needles in my legs and arms. Maybee Im being parinoid but this isint supposed to be a good sign.

Does the flagyl neuropathy last this short?
It seems strange. I only had it for 5 minues.

It was not a herx type feeling,, I usually get severe burning all over my sking especially my feet from the biaxin early on,.

Thanks in advance!!


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pq
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LH,

I had this flagyl-induced numbness, and stopped it 2 days after it started, thinking this was a neuropathy.
I stopped the flagyl as a precaution.
Check w/ your doc., or drug books,and sites for indications on when to stop.

As best I recall, I think this is an indication to stop the flagyl, at least temporarily.

Best to err on side of safety, and check drug sources until you get an answer.

pq


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lymeHerx001
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Right,, the LLMD says

"ohh 250mg twice a day will be fine."
No side effects....

"should I start off lower?" I asked...

Nah,,,

Yea right,, I know better , im taking it slow
I see him on Friday ---woo hoo!!!!


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lymeHerx001
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anyone else?

I keep taking more and more slivers tonight and I feel slight pins and needles..

I want to be better so Ill struggle through this.

No major herx though.


Anyone else on this board continue with flagyl even though it gave them the sensation of pins and needles?


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lymeHerx001
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should I stop taking this?
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Areneli
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.. or check my post on minocycline and cysts.

Perhaps what you feel is cysts breaking.
If you have plenty of them and they break all the time it may look like needles.
With time it should be less.

Too early for neuropathy


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lymeHerx001
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When you say its too early for neropathy that means what?

It builds up overtime?

It doesnt feel painfull just numb and like pins and needles,,like they fell asleep.

In my hands and in my feet and actually my scalp.


I had true neuropathy from the biaxin and that was PAINFULL,, felt like sunburn.

My feet swelled a little turned purple and BURNED like they were being dipped in hot acid.


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pq
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Sophmore = Wise Fool

You can always go back to it.

Find out if flagyl-induced neuropathy is permanent or reversible. If you take it long enough without a break you'll know for sure, either way.


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Areneli
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Polyneuropathy will take weeks (if ever) to develope. It has to do with transportation systems in fibres. It won't happen overnight.

I still suspect you feel the same thing that I feel: breaking cysts - and it is a good sign.


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lymeHerx001
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wow some discrepancy on this board.

It makes sense Areneli.
How do you know so much about flagyl?

Do you work in the medical field or did your doctor inform you?


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lymeHerx001
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bump
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treepatrol
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Areneli's Other Post
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treepatrol
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Flagyl Oral
Active Ingredients: Metronidazole Oral
Representative Names: Flagyl Oral, Metric 21, Protostat
Available Product Images:

What are metronidazole tablets or capsules?
What should my health care professional know before I take metronidazole?
How should I take this medicine?
What if I miss a dose?
What drug(s) may interact with metronidazole?
What side effects may I notice from taking metronidazole?
What should I watch for while taking metronidazole?
Where can I keep my medicine?

What are metronidazole tablets or capsules? (Back to top)
METRONIDAZOLE (Flagyl�) kills or prevents the growth of certain bacteria and protozoa (single cell animals). Metronidazole treats infections of the skin, central nervous system, bones and joints, respiratory tract, abdomen, gynecologic and vaginal infections (including trichomoniasis), and intestinal infections (including dysentery). Generic metronidazole tablets and capsules are available.

What should my health care professional know before I take metronidazole? (Back to top)
They need to know if you have any of these conditions:
*if you drink alcoholic beverages
*anemia or other blood disorders
*liver disease
*disease of the nervous system
*seizures (convulsions)
*other chronic illness
*an unusual or allergic reaction to metronidazole, or other medicines, foods, dyes, or preservatives
*pregnant or trying to get pregnant
*breast-feeding

How should I take this medicine? (Back to top)
Take metronidazole tablets or capsules by mouth. Follow the directions on the prescription label. Swallow tablets or capsules whole with a full glass of water. You can take this medicine with food or milk. Take your doses at regular intervals. Do not take your medicine more often than directed. Finish the full course prescribed by your prescriber or health care professional even if you think your condition is better. Do not stop taking except on your prescriber's advice.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose? (Back to top)
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What drug(s) may interact with metronidazole? (Back to top)
*alcohol or alcohol-containing beverages or medicines
*amprenavir
*barbiturate medicines for inducing sleep or treating seizures (convulsions)
*carbamazepine
*cimetidine
*disulfiram
*fluorouracil
*lithium
*methadone
*phenytoin
*sirolimus
*tacrolimus
*warfarin

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What side effects may I notice from taking metronidazole?
Side effects that you should report to your prescriber or health care professional as soon as possible:
Rare or uncommon:
*clumsiness, dizziness, or unsteadiness
*fever or chills, sore throat
*numbness, tingling, pain or weakness in the hands or feet
*seizures (convulsions)
*skin rash, itching
*vomiting or severe stomach pain
More common:
*unusual tiredness or weakness
*vaginal irritation or discharge

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):
*dark brown or reddish urine
*diarrhea
*dry mouth
*food tasting unusual or like metal
*headache
*loss of appetite
*nausea
*mild stomach pain or cramps

What should I watch for while taking metronidazole?
Tell your prescriber or health care professional if your symptoms do not improve in 2 or 3 days.

If you are taking this medicine for a long time you must visit your prescriber or health care professional for regular blood checks.

Avoid alcoholic drinks while you are taking metronidazole and for 3 days afterwards. Alcohol may make you dizzy, feel sick, and flushed; give you headaches and stomach pains.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how metronidazole affects you. To reduce the risk of dizzy or fainting spells, do not sit or stand up quickly, especially if you are an older patient.

Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water will help.

If you are being treated for an infection of your sex organs, your sexual partner may also need treatment. You can use a condom to stop reinfection of you or your sexual partner.

If you are going to have surgery, tell your prescriber or health care professional that you are using metronidazole.

Where can I keep my medicine? (Back to top)
Keep out of the reach of children in a container that small children cannot open.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light. Keep container tightly closed. Throw away any unused medicine after the expiration date.


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lymeHerx001
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Areneli said that she was on MINO not flagyl.

It was determined in the other post that it was nerve irritation not the cysts breaking.

It does say that Flagyl causes nerve irritation.


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lymeHerx001
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Just talked to the LLMD.
He said that there was a possibility that it was the cysts popping that I was feeling.

He said that the Flagyl induced neuropathy usually happens after a long time.

He might be smart in some ways but he doesnt know everything.


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hobokinite
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Be careful with Flagyl. six years later I still have damage from it! If you have any chemical sensativities or aweak liver, or trouble detoxing, get off of it!
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StrengthToStrength
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I would stop taking the Flagyl if I were you, and start taking some ALA supplements. After a while, consider switching to tinidazole, it's less damaging.

You do not want permanent neuropathy in your hands and feet. Imagine not being able to walk without pain, and not having much of a sense of touch in your fingertips. This is what happened to me, and it's about as un-fun as having Lyme. I'm slowly recovering feeling with high dose ALA supplementation, but it's very slow.


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treepatrol
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Areneli
my reply to him in my post above link Areneli's other post.

I doubt your feeling the cyst forms breaking.
Its nerve pains. Lyme causes that.
The cyst's you speak of aren't very big there microscopic.
Spirochetes Pics Link
SPIROCHETES FORMS 1
http://flash.lymenet.org/ubb/Forum5/HTML/000586.html

SPIROCHETES FORMS 2
http://flash.lymenet.org/ubb/Forum5/HTML/000587.html

SPIROCHETES FORMS 3
http://flash.lymenet.org/ubb/Forum5/HTML/000588.html

SPIROCHETES FORMS 4
http://flash.lymenet.org/ubb/Forum5/HTML/000589.html


Flagyl causes that I continued but if it becomes to much lighten up. Its oersonal choice between you & llmd.

[This message has been edited by treepatrol (edited 10 March 2005).]


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lymeHerx001
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Now I dont know what to think!

I just want to get better.


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lymeHerx001
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Hobokinite:

How much Flagyl were you taking and how long were you on it?

Did you have severe side effects on it that led to the permanent damage?

quote:
Originally posted by hobokinite:
Be careful with Flagyl. six years later I still have damage from it! If you have any chemical sensativities or aweak liver, or trouble detoxing, get off of it!


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treepatrol
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I took flagyl on and off for 3.5 years 3to4 months at a time. Some of theside effects yes tingly etc it went away after a while. Talk to your llmd personaly I stayed on it.
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Areneli
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Why don't you switch to Tinidazole for a few days? It costs more money but it is basically chemically very similar to Flagyl but chance that it will cause neuropathy is MUCH smaller. Will you feel better?

I bet you will feel the same popping, because these are the cysts.

Anyway, for now I stick to the cysts disintegration hypothesis as it fits the best my observation.


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lymeHerx001
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Right now I feel a little itchy.

I took 1 and 1/2 pills today.

I just took the last one an hour ago with food and I know that its making me itchy.

All over my body,,, not tooo bad but enough to want to scratch.


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treepatrol
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the LLMD says
"ohh 250mg twice a day will be fine."
No side effects....
That sounds like enough I think your going to be alright did talk too your llmd?

I was taking 250mg 3 x a day but Iam a big fellow and he llmd monitored(bloodwork) my liver every 2 months at first it was every month for a while bu my body seemed to handle it okay.

Dont drink any alcohol ever while takeing flagyl can have sever reactions.


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treepatrol
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lymeherx I found somethin for you.


This drug may also be prescribed to relieve itching associated with gallbladder obstruction.

Questran

Matbe something is doing this to your gallbladder ? Lyme? ?Biaxin? Flagyl?



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lymeHerx001
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Very interesting,,,

Thank you for your care and information.
Ill will print out this thread and bring it to my LLMD today.

If I dont get snowed in that is..........


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treepatrol
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Oky Doky
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lymeHerx001
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Now that I read your post over again , the itching was right after I took the flagyl.

I took 2 pills yesturday and at night I was itching so much.

I woke up and coulndt go to sleep for an hour because of the itching.

Wonder what it is,, side effect, allergy, does it go away? Ill be talking to the doctor today. Hopefully he wont be short on words.


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hobokinite
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I was on it six years agoo forgot dose. After maybe 3 or 4 days I couldn't take it anymore. I received severe chemical sensativities and nerve pain after it. Maybe probs with liver. It comes and goes but That drug was bad for me. Mind you, i was very sick to begin with. Try the other, milder version perhaps. I know The lyme world is confusing. Which way to go??/ What drugs to take? What natural stuff to take? i ask God to give you guidence or just plain heal you!
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lymeHerx001
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Yes, I do agree, GOD can heal.

However one must have purpose to live and feel worthy of it.

The flagyl I think cleared my head a little but its tough to tell at what cost.

Maybee the itching is from the yeast die off?


I do not yet have a herxheihmer from it even after 4 days.


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Areneli
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You must consider sensitivity to Flagyl particularly if the problem would get worse. Can happen with any drug.

Perhaps this drug is not for you.


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pq
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Itching correlates with liver difficulties.
The gallbladder store the stuff the liver makes.


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lymeHerx001
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Met with the LLMD for an hour today.


DRilled him as usual.

He said that the itching and knee pain was a good sign. He told me to take some benedryl,, so ill just take my allegra.

The pharmicist said to watch for rash or hives or swelling of lips or tougue,, the doctor DR. S said the same thing.

I said how long should I be on flagyl and then he said : Do you want to get better?

He said I can stay on it for months,, we need to pop those cysts.

When I asked him if flagyl was good for the neuro stuff he said no. He doesnt know how that can help. Only plaquinil is better for the joint pain.. There are only 3 cyst poppers./

Then I said,, well if my brain is loaded with cysts are they affecting my memory and concentration and mood...@???

Are the cysts harming anything or are they active... He couldnt give me an answer, he said he didnt think they were harming anything.

So ill keep taking the flagyl untill I die I guess... Thats when Ill have my true answer.
At least to all those who frequent this board and to the Oh so famous doctor Zijad.


I just want my vertigo to clear up and to feel some hope of LIFE like all of us.


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Areneli
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This may be some kind of a test where you are with your treatment:
If you have no longer needles after Flagyl perhaps you are on your way to recover and may some time soon stop antibiotics - hopefully permanently.

I have switched to Amoxicillin but even if I no longer take Minocycline (that in my opinion destroys cysts if given in large dose) I still have a small number of 'cyst popping'. Apparently, Minocycline has some delayed action on cysts. I may consider switching to Mino from time to time for a week or two apply dose 400 mg. It seems to be a good idea.

After two months of suffering on antybiotics I no longer have huge herxes on 12 g of Amoxicillin that I take now.
That means that majority of my bugs in my body have been killed.

Still, there are plenty of cysts to pop in my body and the brain to pop and free bugs in the brain to kill.

[This message has been edited by Areneli (edited 12 March 2005).]


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lymeHerx001
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Im feeling somewhat better on the flagyl,,
No herx, and no pins and needles the way I was getting;.

Still just very itchy.
Im keeping on the lok out for a rash and breathing dificulties etc


I just cant belive that the doctor said that this was a good sign and it means that it is working.

Then in the next paragraph he said that the BIAXIN (which is what Im on) works great with plaquinil.

So I said then why dont you put me on that!!@??

He said,,, ohhh;:::::well wait and see what will happen (in his bosnian accent)


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Areneli
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Hearing about people getting clear mind after good treatment with Flagyl makes me thinking that that these darn cysts are not as dormant as we tend to think about about them, they LEAK bacterial venom all the time. I don't see another plausible explanation. Once you open some of them with Flagyl, get through terrible herx, get rid of the toxic cyst contents, you end up with less poison in your brain, so your thinking improves.
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lymeHerx001
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Sounds plausable to me.

I need some more responses!!

Is it possible to just continue to feel better on the flagyl without a major herx???

Cause thats what Im feeling, a week on it allready and Im in less pain, my fog is clearing a little and Im less tired.

Is this possible?
Or is it another manefestation of my mind HMMHOO

[This message has been edited by lymeHerx001 (edited 13 March 2005).]


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lymeHerx001
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any other flagyl users out there?
Who pulses it

[This message has been edited by lymeHerx001 (edited 13 March 2005).]

[This message has been edited by lymeHerx001 (edited 13 March 2005).]


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lymeHerx001
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metronidazole
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Areneli
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Is it possible to just continue to feel better on the flagyl without a major herx???

I don't think so


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lymeHerx001
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Thanks for you input arenelli.
Actually It doesnt make sense to me at all.

Unless its suppressing the cysts ability to thrive? hmm'


I had a kinesiologist muscle test me about 6 months ago and he said that I tested positive for Chylamidia, I think its possible that the Flagyl is hitting that and this could be some type of co-infection.

Either way "we will see what will happen"

I will keep this thread posted at this most interesting time in my life.


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Im thinking now that the dosage of flagyl is not enough for me to herx yet.

I have only been on 250mg twice a day for 4-5days.

I hear people going up to 1500mg a day. More then 3 times my dosage.

That could be why I have some herx type symptoms,, fatigue knees hurt depression ...after I take the pill and then in an hour I feel great!

I dont get it... however I would like to and not be ignorant.


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Does anyone on this board take Flagyl 500mg 3 times a day?
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hopeful123
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lymeHerx001,

I am not on Flagyl because of neuropathy problems. I am on Tinidazole, instead AND mino. Can't remember the dossage. Tini on five, off 2 - 3x a day. I haven't had any major herxes with Flagyl or these two. Maybe lots of minor ones, but nothing that knocked my socks off.

Wanted to stay on Flagyl because it was so immediately good at clearing the brain. In days I felt sharper, was able to function better, etc. But the neuropathy in the legs was not an option.

If you can stay on Flagyl, then go for it, I say.

I feel that my new cocktail is okay, but very slow and I'm getting impatient, too.

It's hard to go back and forth in feeling wellness, cause you're always comparing now to when the meds were helping more, let alone, before you got sick.

Anyway,
good luck with whatever you do.

hopeful123


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lymeHerx001
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Thank you for your reply hopeful.
Wanted to stay on Flagyl because it was so immediately good at clearing the brain

Exactlly,, I thought it couldnt be that I would surelly herx right away. So far some small herxes and a clearer head. Still have the constant vertigo and MCS which contributes to the fog but...

You experience with flagyl sounds like mine.
Havent had neuropathy yet, hope to never on this. The BIAXIN herx gave me terrible burning. It felt like someone was dipping my legs in hot acid.

[This message has been edited by lymeHerx001 (edited 14 March 2005).]


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Still just feeling better on the flagyl.

I have some itching right after I take it and then my skin feels much better and Im in less pain.

I like this drug. Its doing something.
No nasty herxes yet, still on 500 mg a day.

I wonder how high I can go and for how long.


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Areneli
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Ceiling is 3 times 500 mg per day or perhaps 2 g per day. But go there slowly and take breaks. Also try safer tinidazole that does about the same.
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tinidazole sounds like its in the same family?


I know Zithromax, Biaxin, and Ketek are in the same family. However I had a much worse herx on Biaxin then the zith. The zith just upset my colon and gave me burning at the exit point.

Didnt try the ketek yet.


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