I just read the recent 2005 Lyme disease guidelines by Dr.B & again he states that some documentation has shown Flagyl to be less effective when used with Minocycline.
I have looked up a lot of Lyme research & can't find what he is alluding (sp.? sorry) to. Anyone know?
I go to Dr.J in NC & he has me tripeled w/Mino, Ketek & Flagyl.
Just wondering.
Thanks,
current non-fiddler :{.
Posts: 58 | From Leonardtown, Md, usa | Registered: May 2003
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Melanie Reber
Frequent Contributor (5K+ posts)
Member # 3707
posted
Good question Fiddler,
I too am on Mino and pulse in Flagyl. Hopefully, one of the med-experts will come along soon.
Melanie
Posts: 7052 | From Colorado | Registered: Mar 2003
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posted
I have been asking Dr Burrascano to explain that perticular point (no cyclines with an imidazole like flagyl or tinidazole) for YEARS! He never explained.
I could only find ONE article based on ONE person not responding to that combo! Yet Dr B always syas this year after year in his guidleines. I too would really like to know if this is an Urban Myth of Lyme or if there is any real reasoning behind it
Maybe someone else (a patient of his?) can ask him why he says no cycline with an imidaeole.
Nelly (in France)
Nelly
Posts: 416 | From france | Registered: Oct 2001
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posted
This comes up quite a bit. He doesn't seem to have any concrete reason for saying this, other than a warning in the literature that Tetracycline and Oxytetracycline "May" be an antagonist to flagyl or Tini. That does not include Mino or Doxy according to the manufacturers. He has his own opinions about things, and still uses flagyl over Tini even though studies show that Tini is much more effective as a cyst buster than flagyl. Many patients have reported using them together with success on this board.
-------------------- You're only a failure when you stop trying. Posts: 945 | From U.S | Registered: Oct 2004
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posted
I have not investigated the basis for Burrascanos statement, dont have time.
However my best improvement has been on doxy + tini (which I have taken for the last 4 months or so) and I will be continuing this combination indefinitely.
Posts: 62 | Registered: Oct 2004
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posted
I take 1 g tini with 200 mg doxy in the morning, and the same at night. Thus 2 g tini and 400 mg doxy per day.
I'm a 24 year old man weighing about 133 lbs (and weighed the same in health).
My script is for 300 mg /d doxy, not 400, and I have not actually researched the safety issue for the slightly higher dose. Therefore I dont mean to suggest that 400 mg is necessarily safe at my weight; I dont know.
Retrospectively, I was mildly systemically ill in May 2003, then had pelvic pain beginning in Nov 2003. I attributed increasing systemic symptoms to stress from the pelvic pain, until Jun 2004 when they reached extreme severity. Flu symptoms and severe neuro/psych hell; I was house-ridden and was in bed at least half the day, the other half slumped way down in a chair. At my worst I couldnt walk 100 yards but I stabilized at a range of 1 mile. Some days I could only read for 20 minutes at a time before reaching total exhaustion. I had a spontaneous partial remission for a few weeks in Aug 2004; no significant fluctuations happened afterward.
I planned to kill myself, but I had learned from dealing with my pelvic pain that there might be a pathogenesis and recourse that my GPs didnt know about. I learned about bacterial causes of CFS on the internet in Sept 2004, and started antimicrobials (including, a little later, antiprotozoals) in Oct 2004. Progress was very slow, and last spring I still felt like I was 100 years old, and still serious about suicide as a long term prospect. But I started dragging myself to intro bio and chem courses part time. I incorporated tini starting in May. I now feel 90% improved, and glad to be alive. Recently I have been able to exercise aerobically, at subnormal capacity but without any next-day consequences. I'm preparing to attend grad school in bacteriology, and have been working well over 40h/week for several months. However I have only been quite this well for a month and I hope it will not prove an aberration.
Posts: 62 | Registered: Oct 2004
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Glad it has helped you so much. I was taking Tini at 500, then 750, and then 1000 mg Bid for a while. It does help me, as I do have a protozoal parasite infection (B. Hominis) that I can't get rid of. There was someone else that use to post here that got well using Tini 1000 mg Bid for almost 2 yrs in combo with other meds. She has been off meds for about a year now.
-------------------- You're only a failure when you stop trying. Posts: 945 | From U.S | Registered: Oct 2004
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