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» LymeNet Flash » Questions and Discussion » Medical Questions » Zithromax- how long, how much?

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Author Topic: Zithromax- how long, how much?
Areneli
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My doctor is concerned that Zithro may be hepatoxic and reluctant to prescribe for more than 5 days.

What is your experience with this ABX?

How long did you take it and in what doses?

Have you had any side effects?

[ 17. November 2005, 09:26 AM: Message edited by: Areneli ]

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imanurse
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I am on about day #50 of 200mg BID.

My chem profile and enzymes have been normal. I also take Diflucan.

Normal effect of diarrhea at first and major herx, herx has lessened somewhat. No side effects per say.

--------------------
**Eat Chocolate**

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Christian1975
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im on my 3rd month of zith (150 mg a day) combined with flagyl. I dont feel any really bad side effects. My LLMD has a lot of patients that get the same treatment.
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WildCondor
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These dose you guys are mentioning are so low!
My Iv dose of Zithromax was 1000 mg, and my oral dose was 1200 mg per day. Usually you start out at 500 mg IV, or 600 mg orally. [Cool]

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treepatrol
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Zithromax
Active Ingredients: Azithromycin
Representative Names: Z-Pak, Zithromax
Available Product Images:

What are azithromycin tablets?
What should my health care professional know before I take azithromycin?
How should I take this medicine?
What if I miss a dose?
What drug(s) may interact with azithromycin?
What side effects may I notice from taking azithromycin?
What should I watch for while taking azithromycin?
Where can I keep my medicine?

What are azithromycin tablets? (Back to top)
AZITHROMYCIN (Zithromax�) is a macrolide antibiotic that interferes with the growth of bacterial cells. It is used to treat bacterial infections in many different parts of the body. Azithromycin also treats sexually transmitted vaginal or urinary tract infections caused by chlamydia. It will not work for colds, flu, or other virus infections. Generic azithromycin tablets are not yet available.

What should my health care professional know before I take azithromycin? (Back to top)
They need to know if you have any of these conditions:
*kidney disease
*liver disease
*pneumonia
*stomach problems (especially colitis)
*other chronic illness
*an unusual or allergic reaction to azithromycin, other macrolide antibiotics (such as erythromycin), foods, dyes, or preservatives
*breast-feeding

How should I take this medicine? (Back to top)
Take azithromycin TABLETS by mouth. Follow the directions on the prescription label. Swallow tablets whole with a full glass of water. Azithromycin tablets can be taken with or without food. Take your doses at regular intervals. Do not take your medicine more often than directed. Finish the full course prescribed by your prescriber or health care professional even if you think your condition is better. Do not stop taking except on your prescriber's advice.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose? (Back to top)
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses. There should be an interval of at least 12 hours between doses.

What drug(s) may interact with azithromycin? (Back to top)
*antacids
*astemizole
*digoxin
*dihydroergotamine
*ergotamine
*magnesium salts
*terfenadine
*triazolam
*warfarin

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What side effects may I notice from taking azithromycin? (Back to top)
Side effects that you should report to your prescriber or health care professional as soon as possible:
Rare or uncommon:
*dark yellow or brown urine
*difficulty breathing
*severe or watery diarrhea
*skin rash, itching
*irregular heartbeat, palpitations, or chest pain
*vomiting
*yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):
*diarrhea
*dizziness, drowsiness
*hearing loss
*headache
*increased sensitivity to the sun
*nausea
*stomach pain or cramps
*tiredness
*vaginal irritation, itching or discharge

What should I watch for while taking azithromycin? (Back to top)
Tell your prescriber or health care professional if your symptoms do not improve in 2 to 3 days. Contact your prescriber or health care professional as soon as you can if you get an allergic reaction to azithromycin, such as rash, itching, difficulty swallowing, or swelling of the face, lips or tongue.

Keep out of the sun, or wear protective clothing outdoors and use a sunscreen. Do not use sun lamps or sun tanning beds or booths.

If you get severe or watery diarrhea, do not treat yourself. Call your prescriber or health care professional for advice.

Antacids can stop azithromycin from working. If you get an upset stomach and want to take an antacid, make sure there is an interval of at least 2 hours since you last took azithromycin, or 4 hours before your next dose.

If you are going to have surgery, tell your prescriber or health care professional that you are taking azithromycin.

Where can I keep my medicine? (Back to top)
Keep out of the reach of children in a container that small children cannot open.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.

--------------------
Do unto others as you would have them do unto you.
Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.

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Areneli
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WildCondor,
How long you were on these high doses?
Months, years?

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Christine202
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Not everyone does well or succeeds on high dose abx... 600Mg of Zithro nearly killed me... I got better with low dose abx... so I guess we are all different.
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karatelady
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I'm on 500 mg. Zithromax and 500 mg. Ceftin
I had to cut it in half because herxing was way too much. I'm on my 3rd month.

Now I'm up to 2/3 of it and I'm pulsing it 10 days on, 5 days off. Hopefully, to give the cysts time to come out of hiding and to give me a break!

Also doing Heparin shots 2 X day, Samento and Cumanda.

Sandy

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johnlyme1
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I was on 1000 a day oral of zith for 52 days while pulsing malaron and art. At the end I was getting yesast issues
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micul
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I was on 600 mg for 4 months with Mepron and artemisinin. I had 2 months off of it, and now I have been on 500 mg for the past 2 months with Mino for bart. I think that Ketek is far worse as far as hepatoxicity goes. What concerns most Dr's is the very long half life of Zith.

--------------------
You're only a failure when you stop trying.

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Boomerang
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quote:
Originally posted by micul:
I was on 600 mg for 4 months with Mepron and artemisinin. I had 2 months off of it, and now I have been on 500 mg for the past 2 months with Mino for bart. I think that Ketek is far worse as far as hepatoxicity goes. What concerns most Dr's is the very long half life of Zith.

My gosh.......I don't mean to be a downer.....but these long, long periods of antibiotics that everyone talks about just depresses me.

What do you mean about the long half life of Zith?

Thanks.

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WildCondor
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I started at 500 mg IV Zithromax for 3 weeks, I then increased to 1000 mg IV Zithromax 3 days a week with the 500 mg 2 days a week all those for 6 months.

Oral Zithromax I started at 600 mg for a month, then increased to 1200 mg daily and took that for over a year. In addition to that I also took IM Bicillin shots and Flagyl and never had any problems.

You have to remember that when you take those tiny doses, only part of the medication is actually absorbed. You likely are not getting enough, unless you are combining it with something else. When i did it with Mepron it was 1200 mg per day and 3 teaspoons Mepron a day, now they are using 4.

Hope that helps, it worked great!

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WildCondor
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Regarding half life of Zithromax...what they meant was that it stays in your system for a few days so you can take a weekend off of it if you are doing IV, etc.
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