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» LymeNet Flash » Questions and Discussion » Medical Questions » Concerned - No herxing on 200 ml. Doxy

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Author Topic: Concerned - No herxing on 200 ml. Doxy
Dalphia
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Have a concern that I'm not herxing on Doxy.-200 ml. daily. Haven't ramped up on Doxy. yet since I've only been on it for 3 weeks. I've been on Famvir for Epstein Barr for over 2 months and the herxing was terrible. I thought when beginning the Doxy. for Lyme that herxing would continue, however, I'm just not experiencing any. So, I'm wondering if the Doxy. isn't killing off any of the Lyme bacteria. And, I have a concern that it might be possible with this small dose the bacteria can go hide even deeper within the cells. Does anyone have any experience regarding this or give any advise. Thanks, Dalphia (Gaye)
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JimMet
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I started on doxy 100mg BID b/c my MD didn't know how to treat Lyme. My symptoms continued to worsen. After I read Dr. Burrascano's article at www.ilads.com and learned that doxy won't help in low concentrations b/c it isn't bactericidal nor will it penetrate the blood-brain barrier in this dose, I upped it to 200mg BID. Within days my symptoms began disappearing.

You may not be taking enough.

Good luck!

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Dalphia
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Jim, thanks, that is good information to know. And, thanks for inserting the website. I believe you are right, I just don't feel as if anything is happening on this amount of Doxy. Again, thanks for responding to my post. Gaye
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Dalphia
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Jim, one more question. After you upped the Doxy. to 200 mg. did you experience a major herx. or was it just minimal? Guess I think if I'm not herxing then the medications aren't working to kill off the bacteria/virsus, etc. Thanks,
Gaye

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Dalphia
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Jim, one more question. After you upped the Doxy. to 200 mg. did you experience a major herx. or was it just minimal? Guess I think if I'm not herxing then the medications aren't working to kill off the bacteria/virsus, etc. Thanks,
Gaye

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Ewok
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Somewhere on this site I read the dose was 100mgs per 50 lbs. I weigh 134 and my LLMD had me on 400mgs --200mgs 2x a day. I experienced some nausea but not herxing. According to a fancy LLMD duck in CT--not everyone has to herx. That's new info. Be careful doxy is extremely photosensitive--at least it was for me.
Ewok

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Frecker777
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Hey Dalphia,
I have been on 400 mg doxy for 5 weeks with no herx and wondering the same thing. When do you know an antibiotic is not personally effective and a new one needs to be tried?
-Carrie

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Ewok
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Carrie,

My LLMD said you should feel better or worse (herx) but if nothing's happening after a month you may need to try something else. I talked to a woman yesterday who cured herself of LD and co-infections with Cat's Claw...the Samento brand by nutramedix.com

Ewok

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Dalphia
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Frecker, that is my point, glad you are in agreement. Guess we'll just have to wait and see. We may just have to go with another medication that will work. But, it still doesn't seem quite clear which way we are to go here, if no herxing, again how do we know it is effective with die-off...........I'm still a little confused here. Thanks for your response........
Dalphia

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timaca
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Dalphia~

I was on 200 mg doxy for several weeks and did not herx. My LLMD increased the dose to 300 mg and at day 11 I had a significant herx for 3 days. (I tend to herx somewhere between day 10 and 12).

I felt better after that. Now I'm wondering what would happen if I increase the dose to 400 mg!

Good luck!

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lymelimpliz
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The Dr. Burrascano article on ilads.org website was extremely enlightening and helpful. Here's the link: http://www.ilads.org/files/burrascano_0905.pdf Thanks for the tip! I too am only taking 200mg of Doxy a day but I just started this week so it isn't unreasable that I'm not herxing. But three weeks on Doxy does not necessarily mean you will not herx - but if you don't by the end of four weeks then I would question the effectiveness of your dose. In quoting the bottom of page 16 in Dr. B's article:

"Several days after the onset of appropriate antibiotic therapy, symptoms often flare due to lysis of the spirochetes with release of increased amount of antigenic material and possibly bacterial toxins. This referred to as a Jarisch Herxheimer-like reaction...It has been observed that symptoms will flare in cycles every four weeks...this reflects the organism's cell cycle, with the growth phase occurring once per month...antibiotics will only kill bacteria during their growth phase."

Therefore, according to this article, you herx when the bacteria is in its growth phase which only happens once a month, which is why it is necessary to be on antibiotics for atleast one month. But just because you herx once doesn't mean it's over - that's why LLMD recommend long-term abx usage longer than one month - because you most likely will herx again in another four weeks.

It is ridiculous that some medical practitioners only prescribe abx for two weeks!

Excellent article! It also gives great tips on supplements and diet! Read it if you can - it's easy to skim.

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Boomerang
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Hubby was on 200 mg Doxy for almost four weeks before his first herx.... bright red rash on his face, looked pretty much awful and felt horrible.

Our LLMD says not all people herx, so I wouldn't worry about it. I'd take it as a blessing! Are you feeling better?

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BostonLyme2005
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Hi,

I have heard that not all people do herx, and that not all herx in the same manner. When I was taking 1500 mg's of Amox, I had some strange feelings and pains, thought it was this herx thing everyone speaks of, so I lived with it.

Now, after taking Tetra 1500 mg's for five-six weeks, I have had some REAL herxes! I have had increase in pain in the joints, tingling, numbness, arthritis pain, sleep has been awesome though, no probs there.

I eat very little sugars, caffiene, crapy foods. I do eat lots of yogurt, 3 times a day, 3 hours after my twice daily meds. I am still working, never stopped.

If I could have one wish, it would be that all of us are cured. I would take that over all the $$$ in the world!

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