Boomerang
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Member # 7979
posted
Okay.......this may sound like a dumb question......but I think I just realized something. Back before my hubby was DX with Lyme, and was having neuro problems...he started eating blueberries for his "brain fog". Of course, it didn't help. But he has kept eating them each night.
Even though I've stopped him from eating all other fruit, candy, etc... he continues to eat about a 3/4-1 cup of blueberries every night on his fat free, no sugar, ice cream..........
Don't blueberries have something to do with the B vitamins? Or am I dreaming that?
Wouldn't the blueberries be a bad thing? Man, to think he's done this for every night for the last 10-12 months, thinking it was good for him.
Am I correct in my thinking?
Sorry if this is dumb....
Thanks for any advice.
Posts: 1366 | From Southeast | Registered: Sep 2005
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A and C, zinc, potassium, iron, calcium and magnesium. No B's.
Acai berry does have B's.
A whole bowl of blueberries could potentially cause a herx if you're talking about Bb infection.
They really are that good for you.
While he's at it, have him mix them with raw pineapple chunks. Pineapple has bromlelain and other digestive enzymes in them which help fight yeast overgrowrh, as well as two documented anti-cancer compounds which work in different fashions. The beneficial compounds in these fruits far outweigh the fructose "risks".
Posts: 294 | From nevada | Registered: Sep 2005
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Boomerang
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Member # 7979
posted
Thanks.......gosh, it's frustrating......
TO eat fruit or not eat fruit?
I was just thinking the B Vitamin thing made it bad for him.
It's been tough, cause he loves fruit. Apples, Oranges, bananas. I thought the blueberries were okay.
GiGi
Frequent Contributor (5K+ posts)
Member # 259
posted
No fruit or little fruit would have certainly done me away. I ate all the fruit I wanted, a piece every day, or two pieces every day. A fruit salad made from fresh fruits is a frequent desert for us.
I have no idea who made up this story of no fruit. It goes totally against my rules as to what nutrition is all about. I have never been told by my doctor not to eat fruit. In fact, I have never restricted our diet. A healthy variety of all fruits and vegetables, grains, meats, avoiding all preservaties and artificial color and flavors. I will not touch these.
It really made me realize how easily we can be brainwashed when I ran accidentally into a lady at my docotor's who wrote a Yeast Diet book that I had bought years before. Not because of yeast, but because I could not figure out and didn't know that metal toxicity depressed me. When I realized that the lady was sicker than I or just as sick as I, even though I always thought "she knew it all" and published a book about it and distributed newsletters, I decided to quit listening to people who propagate rules for this and that that really made little sense. The lady is still not quite well, and at this point I feel she starved herself of the most valuable nutrients nature supplies for us. Yeast which she had thought was her problem was not the problem; rather it was mercury toxicity. Yeast is most the time a second event brought on by other causes. Probiotics fine if you are on abx. Heavy sugar-laden stuff - no. Fruit - yes.
There are live nutrients in fruits along with the enzymes that no supplement can give us. I definitely think the fruits were my healing helpers.
Take care.
P.S. Berries are some of the healthiest fruits you can eat. I would not worry about what they contain. Variety is important.
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luvs2ride
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I totally agree on the fruit/sugar issue. I have never believed the sugars in fruit were harmful to us.
God put the food on this earth we need to live and be healthy. Science proves over and again, that the different chemicals in whole food balance each other out in our systems.
The egg is the latest discovery. After so many years of focusing on the high cholesteral content and thinking it was bad for us, they have finally discovered another ingredient in the egg that completely balances the cholesteral effect in our bodies. (sorry, if I were more scientific like some of you here, I could actually name the ingredient)
There is a saying in the natural health world that you should grocery shop around the outer edge of the grocery store only. Everything on the inner isles is processed, preserved, pre-cooked and packaged.
I crave blueberries too. I eat tons of them when they are in season. I didn't know you could herx on them and I never did. But I do believe your body will crave what it needs to eat.
-------------------- When the Power of Love overcomes the Love of Power, there will be Peace. Posts: 3038 | From america | Registered: Oct 2005
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groovy2
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Hi all
Yep - Bluebarries are one for the Best foods you can eat--
They are packed with antioxidents- The highest of any food by many times--
I dont know if they have any ABX quilities but it would not supprise me--
I eat them often--Jay--
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rosesisland2000
Frequent Contributor (5K+ posts)
Member # 2001
posted
I am currently in a possible remission.
Last week I started a new diet I found in First magazine, dated January 9, 2006. You do this for three days and off for 4 days.
Basically the first day you eat protein, then the next two days you eat FRUIT...all day, lot's of fruit.
I agree with Gigi that fruit is a very important part of our diets.
If I have the time today I'll post the diet over in General. I lost 4 lbs the frist go round and I'm not constipated anymore.
5dana8
Frequent Contributor (1K+ posts)
Member # 7935
posted
There is something about blueberry's. This summer when our bush's where full I had a bowel every morning at breakfast.
I felt perty good.After I ate them.It did't always last all day though.
I dont't like the frozen one's and they don't appeal to my stomach any more but I have been thinkin of introducing them again. I wish they sold crushed up blueberrys.Don't have the energy to blenderize.
Take care & think blue
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robi
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posted
I cannot deny the nutritional benefits of fruit. They are many. And many folks should have fruit as part of there diet. Bluberries are a great choice and when I do eat fruit, it is one of the few I eat.
Now, the other side of that is that some folkd cannot eat fruit. I eat no sugar in my diet. When I add fruit, even in small amounts, I gain weight, my fast blood sugar goes up, and my mouth burns(from yeast). Yes, fruit is good .......... but not for everyone.
I would love to be able to eat fruit but even the low sugar fruits are disaterous for me in several ways.
I just wanted to present the other side of the issue here because I knw there are others in my shoes. They want to eat fruit and everyone says "fruit can't be bad", but for some of us it is.
For me I know this because I have controlled my diet and then only added small amounts of fruit and had negative results.
For those that can eat it without problems, that's cool ..... just realize that it is not across the board healthy for all of us.
Thanks, robi
PS It was not until I cut fruit from my diet that I was able to lose 125+ lbs. in 1998. (Cutting fuit was not the only thing I did)
-------------------- Now, since I put reality on the back burner, my days are jam-packed and fun-filled. ..........lily tomlin as 'trudy' Posts: 2503 | From here | Registered: Apr 2004
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blueberries contain quercetin, that is why they work i think. This is antiinflammatory agent, i also noticed changes while eating blueberries even drinking blueberry ffruit tea.
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GiGi
Frequent Contributor (5K+ posts)
Member # 259
posted
Wild Blueberries - in one form or another - eat them and - wild and in the midst of winter - anything to give our body what it needs. I used to pick them in the Black Forest when I was a child in the Thirties. I would have all sorts of complaints to my Mom and Dad because it took so long to fill that little jar.........those berries were so teeeeny, but, I think, we still benefit from them today. There are some things in life that no chemistry formula can replace!!!!!!!!!! These are what we take when snow covers the woods and the store-bought ones look so beautiful they cannot possibly be grown without toxins. Take care.
Wild Blueberry as Observed and Published in Peer Review Journals
Wild Blueberry: Function * Acts as a potent anti-inflammatory agent as measured by reduction of Nuclear Factor-kappa B in the brain, COX-2 in vitro and Isoprostane in vivo. * Acts as a potent antioxidant by increasing antioxidant status in vivo as measured by increased ORAC in bloodstream and reduced level of 8-isoprostanes in blood and urine and reduced lipid-oxidation in vivo.
Wild Blueberry Freeze Dried Extract: Beneficial Health Effects * Improvement of short-term memory loss. * Protection against macular degeneration of the retina * Amelioration of age-related declines in neural and cognitive function. * Reduction of age associated lipid peroxidation, one of the key factors responsible for development of cardiovascular health problems * Suppression of several types of cancer cell growth as reported in peer-review scientific journals. Based on this observation it is expected that blueberry could be helpful in reducing the risk of some cancers and managing cancerous conditions.
Blueberry Plays an Important Role in the Process of Aging
James Joseph PhD, Chief of the Laboratory of Neuroscience at Tufts University ``The brain is a hotbed of free-radical activity. As we age, we seem to become more sensitive to their damaging effects.'' Dr. Joseph wanted to see whether blueberries with all their antioxidant activity, could help protect aging brains. His research made headline news by showing that blueberries confer true ``anti-aging'' benefits. Wild Blueberry, freeze dried extract not only helps prevent declines of old age, but actually reverse brain aging.
Reversal of age related changes in neuronal signal transduction, cognitive, motor and behavioral deficits by dietary supplementation with blueberries was reported in the Journal of Neuroscience. Supplementation with antioxidant rich blueberries was found to improve CNS function in aged animals and humans.
Figure 1. Levels of Isoprostanes in the plasma and urine of young and old rats receiving a normal diet or a diet containing blueberry. Old animals had greater levels of markers of oxidative damage compared to young animals. The blueberry diet reduced this marker for oxidative stress remarkably in the old animals receiving the dietary intervention. Published in: Journal of Undergraduate Research, Volume 2, Issue 5 - February 2001: Nutritional Interventions to Slow Cellular Aging, by Jill Goldstein
Accumulative Oxidative Damage Causes a ``Net Stress'' on Normal Body Functions The result of the Net Stress on the body generates many specific diseases. Net Stress contributes to the general decline of optimum body function and commonly believed to hasten the ``aging process''.
Among the many oxidative stress mediated diseases are: Alzheimer's Disease, Autoimmune Diseases, Cancer, Heart Disease, Cataractogenesis, Diabetes, Macular Degeneration, MS, Muscular Dystrophy, Pancreatitis, Parkinson's Disease and Rheumatoid Arthritis.
Blueberry Enhances Antioxidant Potency in the Human Body
ORAC- The Scientific Standard for Measuring the Anti-Free Radical Potency The scientific standard for measuring the antioxidant potency of foods is currently expressed in ORAC units (Oxygen Radical Absorbent Capacity). The ORAC assay has been extensively utilized in the field of antioxidant and oxidative stress medical research. It gives science the ability to quantify total antioxidant strength of any food, tissue or fluid.
Simply explained, a high ORAC score indicates a high total antioxidant capacity.
Blueberries Tested #1 for Antioxidant Activity The US Department of Agriculture's Center for Aging at Tufts University measured the ORAC activity of more than 40 commercially available fruits and vegetables. The blueberry ranked highest of all.
North American Wild Blueberry has 25-30 different kinds of Anthocyanins An especially potent blueberry concentrated for its antioxidant benefits, wild blueberry is found in the coastal field and barrens of Maine and Eastern Canada.
Only the finest, ripest North American wild blueberries qualify to be used in our product. Our `Wild Blueberry' extract has been put through a unique propriety process that has concentrated the phytochemicals responsible for free radical absorption. Most fruits have 3-5 types of anthocyanins; our wild blueberries have 25-30 different kinds.
Wild Blueberry, freeze dried extract, powerful health benefit is attributed to exceptionally high levels of unique anthocyanins and chlorogenic acid.
Anthocyanins from Wild Blueberry freeze dried extract are Bio-Available It is well known that Vitamin C and Vitamin E are readily bio-available compared with anthocyanins which are more difficult to absorb. The anthocyanin molecule is a vastly more powerful free radical scavenger than vitamins C and E.
However, in food there is .1 to .3 % of anthocyanin and the final amount that reaches the blood is negligible. Therefore, high concentration of anthocyanins must be provided to obtain an appreciable effect. Through the unique proprietary process, Wild Blueberry, freeze dried extract is highly concentrated with anthocyanins and achieves significant levels of absorption and bioavailability.
A study published in 2002 in the Journal of Agricultural and Food Chemistry demonstrated that the serum levels of 19 anthocyanins contained in wild blueberries were elevated significantly after ingestion of Wild Blueberry, freeze dried extract powder. Additionally, the increase of anthocyanin concentration was directly correlated with an increase in serum antioxidant capacity as measured by the ORAC standard.
Dusan Miljkovic PhD, Internationally Renowned Scientist, Comments on Wild Blueberry Freeze Dried Extract ``A variety in phenolic rings and extra attachment of alkyl groups is key to the added free radical scavenging ability. Another bio-molecule, chlorogenic acid, is concentrated in this product. It is an exceedingly potent antioxidant.
In fact when absorbed it converts through hydrolysis into caffeic acid, and caffeic acid has the highest ORAC value ever recorded- 32,000. It is especially effective in crossing the blood-brain barrier. Chlorogenic acid is also anti-diabetic since it prevents the absorption of glucose from the gut.''
Blueberry is Important for Management of Inflammatory Conditions
Mild COX-2 Activity of Wild Blueberry Freeze Dried Extract In studies Wild Blueberry has been found to be a potent inhibitor of COX-2 enzyme in tube test (EC50=53ug/mL) but not COX-1. This observation indicates that Blueberry could be effective in inhibition of COX-2 within human body if very significant amount of the berry could be consumed.
Exploring further anti-inflammatory activity of Blueberry it was found that this material reduces: 1. Nuclear factor kappa B in vivo. This transcription factor is a key regulator of pro-inflammatory conditions 2. 8-isoprostanes in vivo. This molecule reflects oxidative (peroxidation of lipids) and inflammatory status of the body 3. MCP-1 in vivo (Monocyte Chemoattractant Protein -1, one of several chemokines involved in inflammation process). This chemokine is involved in the process of atherogenesis, stroke, arteriosclerosis, and inflammation induced by oxidized LDL, arthritis.
Zbigniew Pietrzkowski PhD, Comments on Arthritis and Inflammation Dr. Zbigniew Pietrzkowski, a world class molecular and cell biologist, comments on blueberry's ability to reduce isoprostanes, a very important marker for pro-inflammatory prostaglandins: ``Inflammatory prostaglandins are the result of the enzymatic breakdown of arachidonic acid, and a major causative factor in arthritic disease.
Isoprostanes are the downstream marker of this oxidative process. They are most ideal to follow the oxidative process because they are generated from excess oxidatives or by lack of antioxidants. Blueberry's ability to reduce levels of Isoprostanes indicates its usefulness in mediating this chronic inflammatory condition.''
Cancer and Inflammation Development of cancer is associated with local pro-inflammatory conditions and often pro-inflammatory proteins are over-expressed and secreted by a wide variety of neoplasias (formation of tumors) such as colorectal, gastric, liver, pancreas, esophagus, lung, skin, breast,
However, Blueberry may inhibit growth of several types of cancer cells by some other mechanism not necessarily connected to inhibition of pro-inflammatory proteins as published in several peer-review journals. This observation is currently investigated in order to understand the principle of such inhibition.
Aging and Inflammation Increased inflammation level within the body is observed with progression of age. Preventing and/or reducing inflammation conditions are commonly recognized as important strategy in slowing the process of aging.
A new study recently presented from the John Hopkins School of Medicine confirmed the observation published by Joseph et, al showing that blueberries provide safe COX-2 inhibition, improve cognition, and can even reverse-age related declines in brain function.
However, isoprostanes represent now the most significant role in the process of aging confirming that anti-oxidant status and inflammation caused mainly by oxidized LDL are a key factor contributing to accelerated aging anf progression of Alzheimer disease (see last two references).
Prevent and Even Reverse the Accelerating Rise of Today's Complex Diseases The USDA and Tufts University are continually publishing new research on the possible health benefits of Wild Blueberry for anti-aging, cancer, ORAC, vision and UTI.
The 5 A Day For Better Health government/industry campaign intends to help people eat 5 servings of fruits and vegetables a day. The National Cancer Institute found that 42% eat less than 2 servings a day. The average ORAC value of five servings of fruits and vegetables is 2500. The average American serving per day can be as low as 300 ORAC units. One gram (2 capsules) of Wild Blueberry freeze dried extract provides 6500 ORAC units of antioxidant capacity.
One capsule of Wild Blueberry freeze dried extract provides 3250 ORAC which is 150% more than the average American diet, and 30% more then the Five A Day recommended serving.
Wild Blueberry Freeze Dried Extract is 100% Pure BioImmersion, Inc. Manufactures and encapsulates Wild Blueberry without any added Excipients: fillers, binders and flowing agents (such as magnesium stearate). Each vegetarian capsule is only filled with 100% pure Wild Blueberry, freeze dried extract.
BioImmersion Inc. technologically advanced Therapeutic Foods range of products responds to the reality of today's negligible dietary patterns and answers the required nutritional needs to achieve and preserve good health. Our products are extensively and properly analyzed and documented to ensure consistent delivery of the highest levels of active ingredients. Wild Blueberry, Freeze Dried Extract, provides the highest potency ORAC value in the market today.
Key References
Blueberry Supplemented Diet: Effects on Object Recognition Memory and Nuclear Factor-kappa B Levels in Aged Rats Pilar Goyarzu A1, David H. Malin A2, Francis C. Lau A2, Giulio Taglialatela A3, William D. Moon A2, Ryan Jennings A2, Edward Moy A2, Deborah Moy A2, Stephen Lippold A2, Barbara Shukitt-Hale A4, James A. Joseph A4 A1 National Autonomous University of Mexico Mexico City Mexico A2 University of Houston-Clear Lake (Mail Code 237) Bay Area Blvd. 77058 Houston TX USA A3 University of Texas Medical Branch Galveston TX USA
A4 U.S. Department of Agriculture Human Nutrition Research Center on Aging Tufts University
Boston MA USA. Nutritional Neuroscience, Volume 7, Number 2 / April, 2004It has been reported that an antioxidant-rich, blueberry-supplemented rat diet may retard brain aging in the rat. The present study determined whether such supplementation could prevent impaired object recognition memory and elevated levels of the oxidative stress-responsive protein, nuclear factor-kappa B (NF-κB) in aged Fischer-344 rats.
Twelve aged rats had been fed a 2% blueberry supplemented diet for 4 months prior to testing. Eleven aged rats and twelve young rats had been fed a control diet. The rats were tested for object recognition memory on the visual paired comparison task. With a 1-h delay between training and testing, aged control diet rats performed no better than chance. Young rats and aged blueberry diet rats performed similarly and significantly better than the aged control diet group.
Levels of NF-κB in five brain regions of the above subjects were determined by western blotting assays. In four regions, aged control diet rats had significantly higher average NF-κB levels than young animals on the control diet. In four regions, aged blueberry diet rats had significantly lower levels of NF-κB than aged control diet rats.
Normalized NF-κB levels (averaged across regions and in several individual regions) correlated negatively and significantly with the object memory scores. *
The effect of wild blueberry (Vaccinium angustifolium) consumption on postprandial serum antioxidant status in human subjects. Br J Nutr. 2002 Oct;88(4):389-98. Kay CD, Holub BJ. Department of Human Biology and Nutritional Sciences, University of Guelph, Ontario, Canada.
The aim of the present study was to determine whether the consumption of wild blueberries (Vaccinium angustifolium), a concentrated source of non-nutritive antioxidant phytochemicals, would enhance postprandial serum antioxidant status in healthy human subjects.
A single-blinded crossover study was performed in a group of eight middle-aged male subjects (38-54 years). Subjects consumed a high-fat meal and a control supplement followed 1 week later by the same high-fat meal supplemented with 100.0 g freeze-dried wild blueberry powder. Upon brachial vein catheterization, fasting and postprandial serum samples were taken sequentially and analysed for lipids and glucose and for serum antioxidant status.
Serum antioxidant status was determined using the oxygen radical absorbance capacity (ORAC) assay and the total antioxidant status (TAS) assay. The wild-blueberry treatment was associated with a significant treatment effect as determined by the ORAC assay (water-soluble fraction ORAC(perchloric acid (PCA)), P=0.04).
Significant increases in serum antioxidant status above the controls were observed at 1 h (ORAC(PCA) (8.5 % greater), P=0.02; TAS (4.5 % greater), P=0.05), and 4 h (ORAC(total) (15.0 % greater), P=0.009; ORAC(acetone) (16.0 % greater), P=0.007) post-consumption of the high-fat meal. In conclusion, the consumption of wild blueberries, a food source with high in vitro antioxidant properties, is associated with a diet-induced increase in ex vivo serum antioxidant status.
It has been suggested that increasing the antioxidant status of serum may result in the reduced risk of many chronic degenerative diseases. *
Anti-angiogenic property of edible berry in a model of hemangioma. FEBS Lett. 2003 Jun 5;544(1-3):252-7. Atalay M, Gordillo G, Roy S, Rovin B, Bagchi D, Bagchi M, Sen CK.
Laboratory of Molecular Medicine, Department of Surgery, 512 Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Medical Center, 473 W. 12th Avenue, Columbus 43210, USA.
Hemangiomas represent a powerful model to study in vivo angiogenesis. Monocyte chemotactic protein 1 (MCP-1) is known to be responsible for recruiting macrophages to sites of infection or inflammation and facilitate angiogenesis. Recently we have demonstrated that edible berry extracts potently suppress inducible vascular endothelial growth factor expression and in vitro angiogenesis. Comparative analysis of several berry extracts led to the observation that wild blueberry and a berry mix were most effective.
Our goal was to follow up on our findings with wild blueberry and the berry mix (OptiBerry). The present work rests on our current finding that these two berry powders significantly inhibit inducible MCP-1 expression in endothelioma cells. Therefore, we sought to examine the effects of wild blueberry and berry mix in an in vivo model of experimental angiogenesis. Reporter studies showed that the berry powders significantly inhibited basal MCP-1 transcription and inducible nuclear factor kappaB transcription. Endothelioma cells pre-treated with berry powders showed diminished ability to form hemangioma.
Histological analysis demonstrated markedly decreased infiltration of macrophages in hemangioma of treated mice compared to placebo-treated controls. The current results provide the first in vivo evidence substantiating the anti-angiogenic property of edible berries * Monocyte chemoattractant protein-1 deficiency is protective in a murine stroke model. J Cereb Blood Flow Metab. 2002 Mar;22(3):308-17. Hughes PM, Allegrini PR, Rudin M, Perry VH, Mir AK, Wiessner C. Nervous System Research, Core Technology Area, Novartis Pharma AG, Basel, Switzerland.
Inflammatory processes have been implicated in the pathogenesis of brain damage after stroke. In rodent stroke models, focal ischemia induces several proinflammatory chemokines, including monocyte chemoattractant protein-1 (MCP-1). The individual contribution to ischemic tissue damage, however, is largely unknown. To address this question, the authors subjected MCP-1-deficient mice (MCP-1-/-) to permanent middle cerebral artery occlusion (MCAO). Measurement of basal blood pressure, cerebral blood flow, and blood volume revealed no differences between wild-type (wt) and MCP-1-/- mice.
MCAO led to similar cerebral perfusion deficits in wt and MCP-1-/- mice, excluding differences in the MCA supply territory and collaterals. However, compared with wt mice, the mean infarct volume was 29% smaller in MCP-1-/- mice 24 hours after MCAO (P = 0.022). Immunostaining showed a reduction of phagocytic macrophage accumulation within infarcts and the infarct border in MCP-1-/- mice 2 weeks after MCAO. At the same time point, the authors found an attenuation of astrocytic hypertrophy in the infarct border and thalamus in MCP-1-/- mice.
However, these effects on macrophages and astrocytes in MCP-1-/- mice occurred too late to suggest a protective role in acute infarct growth. Of note: at 6 hours after MCAO, MCP-1-/- mice produced significantly less interleukin-1beta in ischemic tissue; this might be related to tissue protection. The results of this study indicate that inhibition of MCP-1 signaling could be a new acute treatment approach to limit infarct size after stroke. * Aging, gender and APOE isotype modulate metabolism of Alzheimer's Abeta peptides and F-isoprostanes in the absence of detectable amyloid deposits. - Yao J, Petanceska SS, Montine TJ, Holtzman DM, Schmidt SD, Parker CA, Callahan MJ, Lipinski WJ, Bisgaier CL, Turner BA, Nixon RA, Martins RN, Ouimet C, Smith JD, Davies P, Laska E, Ehrlich ME, Walker LC, Mathews PM, Gandy S J Neurochem 2004 Aug;90(4):1011-8. Aging and apolipoprotein E (APOE) isoform are among the most consistent risks for the development of Alzheimer's disease (AD).
Metabolic factors that modulate risk have been elusive, though oxidative reactions and their by-products have been implicated in human AD and in transgenic mice with overt histological amyloidosis. We investigated the relationship between the levels of endogenous murine amyloid beta (Abeta) peptides and the levels of a marker of oxidation in mice that never develop histological amyloidosis [i.e. APOE knockout (KO) mice with or without transgenic human APOEepsilon3 or human APOEepsilon4 alleles].
Aging-, gender-, and APOE-genotype-dependent changes were observed for endogenous mouse brain Abeta40 and Abeta42 peptides. Levels of the oxidized lipid F2-isoprostane (F2-isoPs) in the brains of the same animals as those used for the Abeta analyses revealed aging- and gender-dependent changes in APOE KO and in human APOEepsilon4 transgenic KO mice. Human APOEepsilon3 transgenic KO mice did not exhibit aging- or gender-dependent increases in F2-isoPs. In general, the changes in the levels of brain F2-isoPs in mice according to age, gender, and APOE genotype mirrored the changes in brain Abeta levels, which, in turn, paralleled known trends in the risk for human AD.
These data indicate that there exists an aging-dependent, APOE-genotype-sensitive rise in murine brain Abeta levels despite the apparent inability of the peptide to form histologically detectable amyloid. Human APOEepsilon3, but not human APOEepsilon4, can apparently prevent the aging-dependent rise in murine brain Abeta levels, consistent with the relative risk for AD associated with these genotypes. The fidelity of the brain Abeta/F2-isoP relationship across multiple relevant variables supports the hypothesis that oxidized lipids play a role in AD pathogenesis, as has been suggested by recent evidence that F2-isoPs can stimulate Abeta generation and aggregation. * Measurement of F2-Isoprostanes Unveils Profound Oxidative Stress in Aged Rats L. Jackson Roberts, II b, a, 1 and Jane F. Reckelhoffc , BBRC 2001, 287(1), 254-256 a Department of Pharmacology, Vanderbilt University, Nashville, Tennessee, 37232 b Department of Medicine, Vanderbilt University, Nashville, Tennessee, 37232 c Department of Physiology and Biophysics, The Center for Excellence in Cardiovascular-Renal Research, University of Mississippi Medical Center, Jackson, Mississippi, 39216
Free radicals have been theorized to play a causative role in the normal aging process. To date, methods used to detect oxidative stress in aged experimental animals have only detected 2- to 3-fold differences or less between young and aged animals. Measurement of F2-isoprostanes has emerged as probably the most reliable approach to assess oxidative stress status in vivo. Therefore, we measured levels of F2-isoprostanes free in plasma and levels esterified in plasma lipids in young rats (3-4 months of age) and aged rats (22-24 months of age). Plasma concentrations of free F2-isoprostanes were increased dramatically by a mean of 20.3-fold (range 4.3 to 42.9-fold) and levels esterified in plasma lipids were also strikingly increased by a mean of 29.9-fold (range 15.8 to 50.0-fold).
These findings unveil profound oxidative stress in aged rats which adds considerable support for the free radical theory of aging.
BioImmersion, Inc. Mission Statement
BII bridges the gap between the scientific research community and the health practitioner, facilitating dialogue, education and collaboration, bringing forth an extensive and sophisticated portfolio of products and services to enhance the journey towards better health.
[ 23. January 2006, 12:51 PM: Message edited by: GiGi ]
Posts: 9834 | From Washington State | Registered: Oct 2000
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I agree fruit is good for us BUT so many on this site are taking hi dose of antibiotic and I cant help but wonder what that does to the equasion of adding fruit to your regular diet.
I didnt see any mention of the antibiotic part of the equasion in this thread. Any thoughts?????
Posts: 561 | From connecticut | Registered: May 2004
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5dana8
Frequent Contributor (1K+ posts)
Member # 7935
posted
Thanks for the fantastic article on blueberry's GiGi!
Robi:The bioImmersion wild extract freezed dryed caps may contain less sugar than eating fresh ones.?
I am going to try and find this company & see if they have a webb site that sells them.
I always thought there was something to them,because when I ate them this summer I did otice an improvement.Just couldn't stomach eating so many of them .
Thanks so much ,this is very exciting for me Take care
-------------------- 5dana8 Posts: 4432 | From some where over the rainbow | Registered: Sep 2005
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5dana8
Frequent Contributor (1K+ posts)
Member # 7935
posted
Hi I have searched every where and can't find BioImmersion,Inc. where I was hoping to purchase the freeze dried blueberry caps.
eating the real thing is best but I can't stomach them right now.
Does anyone know where to get a good freeze dryed bluberry caps.
I have seen alot of products that sell a version of blueberry's but didn't convince me of their quality.
I really liked the ones in the article how they where harvested and made.
"May the Blue be with you"
-------------------- 5dana8 Posts: 4432 | From some where over the rainbow | Registered: Sep 2005
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Boomerang
Frequent Contributor (1K+ posts)
Member # 7979
posted
Thanks so much for your opinions all...... I feel much better about it now. I cannot imagine why we were told to avoid fruit! I guess for the yeast factor.
If he's not having any digestive problems, then he should eat all the fruit he wants? Darn, this can be frustrating sometimes!!
Natural fruit doesn't "feed the bacteria"? I thought I read that somewhere on this board....?
Thanks again all!
Posts: 1366 | From Southeast | Registered: Sep 2005
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posted
I remember reading some posts a while back that said blueberries made symptoms worse. Do a search. I can't eat fruit, too much sugar for me. It makes my tongue coated & tastes funny.
Every time I ate even a little bit a yeast infection started. After a particularly bad one I gave up absolutely all fruit & grains. The yeast got under control. Now with theralac, I can have a tiny bit of fruit occasionally.
Dana, try calling them. I am pretty certain that Biopure will have them soon. They are working on getting them.
Take care.
Posts: 9834 | From Washington State | Registered: Oct 2000
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5dana8
Frequent Contributor (1K+ posts)
Member # 7935
posted
Thanks very much GiGi.! I have left an e-mail asking how to order the blue berry caps. Will post if the info for anyone else that may be interested Take care
-------------------- 5dana8 Posts: 4432 | From some where over the rainbow | Registered: Sep 2005
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Boomerang
Frequent Contributor (1K+ posts)
Member # 7979
posted
Thanks for your opinion, Hats.
I'm just wondering if the sugars from the frozen blueberries aren't making my husband's progress slower.
We were warned about fruit/sugars from the LLMD, so I've tried to be careful about that for my hubby. That's why I had a "slaps head" moment.
Thanks again everybody! Much appreciated.
Posts: 1366 | From Southeast | Registered: Sep 2005
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Boomerang
Frequent Contributor (1K+ posts)
Member # 7979
lymemomtooo
Frequent Contributor (1K+ posts)
Member # 5396
posted
Our grocery store offers fresh blueberries most of the year..At times, they are very pricey because of how far they have been shipped and being out of season..But probably a better choice than the frozen ones with syrup..
Also I have seen canned blueberries in the canned fruit section..I imagine they are also in a syrup..Perhaps they could be drained and rinsed, removing some of it..
But I am now going to put some in a bowl for my daughter's lunch..Thanks all..lymemomtooo
Posts: 2360 | From SE PA | Registered: Mar 2004
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5dana8
Frequent Contributor (1K+ posts)
Member # 7935
posted
Hi boomerang
I have no interest in selling anything.
I just am excited about the healing property's of blueberry's but can't stomach eating the real ones.
As alot of other people have voiced here because of yeast issues.Just wanted GiGi to post a reply about where I could find bluberry's in capsule form.
I hope you feel happy soon as we all feel grouchy at times fighting lyme. Take care
-------------------- 5dana8 Posts: 4432 | From some where over the rainbow | Registered: Sep 2005
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posted
Dana why cant you stomach eating the real blueberries? If your body tells you its wrong to be eating blueberries shouldnt you be listening to it instead of trying to fool it. It may figure out a way to fool you.
Posts: 561 | From connecticut | Registered: May 2004
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groovy2
Frequent Contributor (1K+ posts)
Member # 6304
posted
Hi all
you have to have candida under control before eating fruit of any type-- Fruit and candida is a NO NO--
I think every one here is saying after you take care of the candida-- then you can eat some fruit--
I personaly dont eat any fruit(except BB) because the candida effect is bad on me
After I get completly well I am going to eat a Huge fruit salid-- MMMMmmmmmm--Jay---
Posts: 2999 | From Austin tx USA | Registered: Oct 2004
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