I haven't posted here in a while. My 4-year old daughter has been on abx therapy with Dr. J for about one year. The very short story is that she's had some backsliding and we're trying to figure that all out. There have been some changes to her abx, and so most recently what she may be experiencing may be a herx - hard for me to tell.
Currently she takes zithro once per day, and omnicef (cefdinir) twice per day.
Anyway, I was trying to think of what's been different. One thing I came up with is that recently I have been giving her a dose of fluoride supplement about the same time I give her the evening dose of omnicef. (we don't have fluoridated water system where I live, and so they recommend that you give supplement to your kids).
I realize the whole fluoride issue is controversial. Right now I'm just wondering if anyone thinks for any reason that the fluoride could possibly be interfering with the absorption of her evening dose of abx. (I asked pharmacist, and he said he didn't think it was a problem).
Thanks very much.
Posts: 18 | Registered: Jan 2005
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Marnie
Frequent Contributor (5K+ posts)
Member # 773
posted
Funny how information comes at the right time...
I JUST found this the other day:
"Some agents have been found to reduce the toxicity of organophosphorus compounds in animal experiments, and they have potential as therapeutic agents in the management of organophosphorus poisoning.
These agents are magnesium, clonidine and fluoride.
Kiss and Fazekas [3] reported control of premature ventricular contractions with intravenous magnesium. Magnesium was considered to counteract the direct toxic inhibitory action of organophosphorus compounds on sodium--potassium ATPase.
It also inhibits acetylcholine release [4].
Singh and coworkers [5] found that intravenous magnesium reversed the neuro-electrophysiological effect of organophosphorus poisoning.
Organophosphorus poisoning can happen from nerve gas agents, several toxic pesticides OR from toxic pathogens.
That sorta explains the decision to add fluoride to our water. At one time they were considering adding tetracycline to our water supply. Now THAT would have been disasterous!
It appears Bb impacts the enzyme that is needed to break down the neurotransmitter, acetylcholine. This leads to too much...until the cells that produce it are exhausted.
In answer to your question...too much die-off too fast it appears.
Posts: 9481 | From Sunshine State | Registered: Mar 2001
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