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» LymeNet Flash » Questions and Discussion » Medical Questions » phosphatidylcholine -who is on it? is it helping? who told you to take it?

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Author Topic: phosphatidylcholine -who is on it? is it helping? who told you to take it?
lpkayak
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i just heard about this from my brother who isn't into lyme but is into supps

he says its good for cog symp and to prevent alzimers

i'm having serious cog prob now and we don't know if they are from lyme or coinfecs or past head injuries

i just would like to hear from anyone what you know about this...i don't start things w/o alot of info anymore.

i'm also asking my llmd...but he didn't bring it up in a recent appt about cog probs

thanks.

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Lyme? Its complicated. Educate yourself.

Posts: 13712 | From new england | Registered: Feb 2004  |  IP: Logged | Report this post to a Moderator
danielb
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i bought a good amount of it... haven't started taking all of my supplements properly because of well *cognitive problems!* and i have so much else to deal with right now... [Frown] i am tryingto follow all of this acetylcholine focus right now, as i think it may be really important though... lets hope someone picks up on this thread.
Posts: 244 | From Ottawa | Registered: Dec 2005  |  IP: Logged | Report this post to a Moderator
lpkayak
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thanks

--------------------
Lyme? Its complicated. Educate yourself.

Posts: 13712 | From new england | Registered: Feb 2004  |  IP: Logged | Report this post to a Moderator
quaicheng
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LLMD has me on it. He sells me the concentrate. Itseems to help little by little.

1/2 tsp day rx. I just glurg from the bottle.

quai

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"In spite of the ever increasing cost of living, it remains quite popular" S. Shackel

Posts: 87 | From walla walla wa | Registered: Dec 2005  |  IP: Logged | Report this post to a Moderator
docjen
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I had many phosphatidyl choline infusions to help with lyme CNS symptoms as well as restless leg syndrome. I was skeptical at first, too, but there is a pretty good amount of literature on the use of phosphatidyl choline and lipid exchange. After I read through the literature I was comfortable with it, and gave it a try. I'm so glad I did! No more restless legs after years of suffering! My other major CNS symtpoms have improved as well. The only drawback is the wear and tear on your veins. In addition to the infusions, I also take 2 phosphatidyl serine capsules at bedtime.

Good luck!

Posts: 393 | From Washington, DC | Registered: Jun 2005  |  IP: Logged | Report this post to a Moderator
TerryK
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I've been taking it for over a year. I feel that it has been of some benefit to my brain function but nothing very dramatic.

My brother on the other hand has had dramatic results with it but not for brain function even though he needs help there.

His liver enzymes went from extremely elevated to almost normal within 4 months of starting. He also started to feel a lot better. We couldn't pin the improvement to anything else.

I wrote an article about it and I'm cutting and pasting it here:

Phosphatidyl Choline is a purified extract of lecithin. Supplements labeled as lecithin usually contain 10-20% Phosphatidyl Choline. When medical researchers refer to lecithin, they are talking about Phosphatidyl Choline.

Phosphatidyl Choline is the major fat in our cell membranes and acts as a supplier of choline. Choline is needed for cell membrane integrity and to facilitate the movement of fats in and out of cells. It is also a component of the neurotransmitter acetylcholine which is why it is the subject of study for a wide range of neurological and psychiatric disorders.

Phosphatidyl choline helps to break down fats. It is reported to be helpful in preventing hardening of the arteries (atherosclerosis) due to fatty plaques in the blood vessels, cholesterol, heart disease, gallstones, liver problems (including hepatitis), neurological disorders, memory loss and depression, high homocysteine levels, tardive dyskinesia, alzheimer's disease, Bipolar disorder and eczema.

Phosphatidyl Choline is a polyunsaturated fatty acid (PUFA) and PUFA's are known to have many positive effects on health.

Eczema
A cream prepared with witch hazel and Phosphatidyl Choline is as effective as hydrocortisone in the topical management of eczema.1

Gallstones
A low lecithin concentration in the bile may be a causative factor for many individuals with gallstones.2

Gastrointestinal Protection
Phosphatidyl choline is a main component of the gastric mucosal barrier. Animal studies indicate that Phosphatidyl choline helps protect against the adverse GI effects of aspirin and other non-steroidal anti-inflammatory drugs without blocking their efficacy.3,4,5 It may also afford some protection for those who have esophogeal reflux from the damage of excess acid on the esophogeal lining.

Heart Disease
Phosphatidyl choline preserves the blood levels of carnitine, one of the body's most essential heart nutrients.

Phosphatidyl choline is a fat emulsifier, breaking down fats and allowing them to be digested better. It helps cholesterol and triglycerides remain fluid and less likely to build up along artery walls. It has been shown to improve the ratio between the LDL (bad cholesterol) and HDL (good cholesterol) and to lower the LDL.

Liver
A diet low in choline impedes the liver's ability to process fats. Abnormal fat metabolism causes the liver to accumulate cholesterol and triglycerides, eventually leading to fatty liver disease which can be fatal.

Dr. Atkins reports that choline supplements can reverse fatty liver entirely.6 He mentions one small study where CAT scans verified that people with fatty liver disease, who took between 1-4 grams of choline chloride daily for 6 weeks, were completely freed of their fatty liver disease.

Phosphatidyl choline has been reported to be effective in preventing hepatic fibrosis in chronically alcohol-fed baboons.

Memory
There is no scientific agreement on the use of phoshphatidyl choline for Alzhiemers Disease. Several studies have not proven it to be helpful but there is controversy about the way the studies were conducted. According to Dr. Atkins, memory enhancement is more obvious in people without alzhiemers disease. He mentions one study in which considerable short term memory improvement was seen in healthy adults when given 10 grams of choline chloride.6,7

Nutrition for the Nerves
Choline is found in breast milk. Infants need it for the production of myelin, the protective coating around nerves and brain cells

Warnings and side effects:
Those with manic-depressive disorder should not take large amounts. At several grams per day some people will experience abdominal discomfort, diarrhea or nausea.

Choline (without the phosphatidyl group) is available by itself in supplements, but taken in high doses (1 gram or more per day) it can make one smell like fish.

Interactions with other nutrients
Pantothenic acid and phosphatidyl choline are both used by the body to make acetylcholine.

Food sources:
Soybeans, liver, oatmeal, cabbage, cauliflower, egg yolks, meat and some vegetables. Lecithin (contains 10-20%) PC is added to some processed foods in small amounts for the purpose of maintaining texture.


References
1. Laux P, Oschmann R, Witch Hazel:Hamaelis Virgincia L. Zeitschrift Phytoher, 1993 14:155-66

2. Encylopedia of Natural Medicine by Michael Murray, N.D. and Joseph Pizzorno, N.D.

3. Dunjic BS, Axelson J, Ar'Rajab A, Larsson K, Bengmark S.
"Gastroprotective capability of exogenous phosphatidylcholine in experimentally induced chronic gastric ulcers in rats", Scand J Gastroenterol. 1993 Jan;28(1):89-94.
Entrez PubMed

4. Leyck S, Dereu N, Etschenberg E, Ghyczy M, Graf E, Winkelmann J, Parnham MJ., "Improvement of the gastric tolerance of non-steroidal anti-inflammatory drugs by polyene phosphatidylcholine (Phospholipon 100).", Eur J Pharmacol. 1985 Oct 29;117(1):35-42.
Entrez PubMed

5. Swarm RA, Ashley SW, Soybel DI, Ordway FS, Cheung LY., "Protective effect of exogenous phospholipid on aspirin-induced gastric mucosal injury.", Am J Surg. 1987 Jan;153(1):48-53.
Entrez PubMed

6. Robert C. Atkins, "Dr. Atkins' Vita-Nutrient Solution : Nature's Answer to Drugs"

7. Sitaram N, Weingartner H, Gillin JC, "Human serial learning: enhancement with arecholine and choline impairment with scopolamine.", Science. 1978 Jul 21;201(4352):274-6.
Entrez PubMed

8.Dodson WL, Sachan DS., "Choline supplementation reduces urinary carnitine excretion in humans.", Am J Clin Nutr. 1996 Jun;63(6):904-10.
Entrez PubMed

Posts: 6286 | From Oregon | Registered: Jan 2006  |  IP: Logged | Report this post to a Moderator
tempe
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What is a good brand, and a good source for it (non-IV, of course).

Thanks!

Tempe

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lpkayak
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thank you very much. i would also like to know good brands and sources.

--------------------
Lyme? Its complicated. Educate yourself.

Posts: 13712 | From new england | Registered: Feb 2004  |  IP: Logged | Report this post to a Moderator
TerryK
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I can't recommend one brand over another but I buy Swanson's brand from Swanson Vitamins and that is the brand my brother takes as well.

This is my husband's website. He is an affiliate for various companies so he does get financial benefit. I wouldn't normally give any links out on this forum to his website (which is why I cut and pasted my article) but this page will give you a few brands and sources without my having to do a lot of work to give them to you.


Phosphatidyl Choline


I know that the 100 tablet bottle from Swansons is not available any longer but the 200 pill bottle is still available.
Terry

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SForsgren
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I use Phospholipid Exchange from BioPure. This is the product that Dr. K discussed at his recent conference.

--------------------
Be well,
Scott

Posts: 4617 | From San Jose, CA | Registered: Jul 2005  |  IP: Logged | Report this post to a Moderator
canefan17
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Is phosphatydal choline the main ingredient Dr K is using in the phospholipid exchange? (to help get herbs/medicine deeper into tissue?
Posts: 5394 | From Houston, Tx | Registered: Aug 2009  |  IP: Logged | Report this post to a Moderator
NanaDubo
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Phosphatidyl choline is the main ingredient in phospholipid exchange but not the only ingredient.

Biopure has a new powdered phospholipid exchange that is less expensive than the liquid (sort of liquid).

My doctor in WA told me I could take phosphatidyl choline but much prefers phospholipid exchange.

Posts: 1129 | From Maine | Registered: Feb 2008  |  IP: Logged | Report this post to a Moderator
   

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