posted
Looked at newbie section and I think i'm poitive but wanted conformation. I'm very weak and my legs are hurting and walking is tough. This has been going on 7 months. here are the results
I will give the positive bands only. The report says Igenx IGM-positive CDC/NYS -positive
23-25++ 31 ++ 34 ++IND 39 ++ 41 ++ 66+ 93+
Igg neg
Yes or No,Thanks to all....Geoff
Posts: 355 | From NY | Registered: Jan 2006
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5dana8
Frequent Contributor (1K+ posts)
Member # 7935
posted
Hey 6t5frlane Welcome to lymenet! yes. positive and you should not wait any longer for treatment.
Do you have a Lyme literate doctor now?
Here are some webb sites that can help with the WB
posted
Yeah! Positive!!! Now you can get better with the help of a llmd!
Here is the Western Blot result interpretation:
WESTERN BLOT
9 cross-reactive for Borrellia 12 specific for Bb 18 unknown 20 cross-reactive for Borrellia 21 unknown 22 specific for Bb, probably really the 23/25 band 23-25 outer surface protein C (OspC), specific for Bb 28 unknown 30 unknown; probably an outer surface protein; common in European and one California strain 31 outer surface protein A (OspA), specific for Bb 34 outer surface protein B (OspB); specific for Bb 35 specific for Bb 37 specific for Bb 38 cross-reactive for Bb 39 is a major protein of Bb flagellin; specific for Bb 41 flagellin protein of all spirochetes; this is usually the first to appear after a Bb infection and is specific for all Borrellia 45 cross-reactive for all Borellia (sometimes people with Lyme who have this band positive also have the co-infection Ehrlichiosis) 50 cross-reactive for all Borrellia 55 cross-reactive for all Borrellia 57 cross-reactive for all Borrellia 58 unknown but may be a heat-shock Bb protein 60 cross reactive for all Borrellia 66 cross-reactive for all Borrelia, common in all bacteria 83 specific antigen for the Lyme bacterium, probably a cytoplasmic membrane 93 unknown, probably the same protein in band 83, just migrates differently in some patients
I hope this helps you I always pay particular attention to the lyme specific bands. Peace!
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-------------------- I'm gonna get that lyme !!! Posts: 61 | From Erie, PA | Registered: Dec 2005
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posted
IgG means a past infection. A lot of people test positive on the IgG and Neg on the IgM and vice versa. I highly recommend IGNORING a rheumatologist and looking for a llmd...they are the only ones up to date with lyme and how to treat it!
-------------------- I'm gonna get that lyme !!! Posts: 61 | From Erie, PA | Registered: Dec 2005
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SForsgren
Frequent Contributor (1K+ posts)
Member # 7686
posted
That is probably much more positive than most which could mean a couple thing:
1) There are more bugs and you are reponding to them OR 2) Your immune system is just better at recognizing them and producing antibodies than the average person
In any event, treatment is definitely warranted. IgM and no IgG COULD mean the infection is recent. However, in Lyme, you see a cyclical nature with these. You may show IgG later, IgM even later, etc. It just seems to go in cycles which is not true of most other infectious processes.
Take a look at my site below also for some additional information.
-------------------- Be well, Scott Posts: 4617 | From San Jose, CA | Registered: Jul 2005
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quote:Originally posted by Gretchen P: IgG is past infection IgM is current infection
Not necessarily.
From Dr C's link below:
"With most infections, your immune system first forms IgM antibodies, then in about 2 to 4 weeks, you see IgG antibodies. In some infections, IgG antibodies may be detectable for years. Because Borrelia burgdorferi is a chronic persistent infection that may last for decades, you would think patients with chronic symptoms would have positive IgG Western blots.
But actually, more IgM blots are positive in chronic borreliosis than IgG. Every time Borrelia burgdorferi reproduces itself, it may stimulate the immune system to form new IgM antibodies. Some patients have both IgG and IgM blots positive. But if either the IgG or IgM blot is positive, overall it is a positive result.
Response to antibiotics is the same if either is positive, or both. Some antibodies against the borrelia are given more significance if they are IgG versus IgM, or vice versa."
quote:Originally posted by 6t5frlane: I do not have a LLMD yet. Going to call DR D. C. in westchester NY
I don't live anywhere near NY, but I would caution you to be SURE to find a Lyme friendly dr! I do have a list of LLMD's and don't see this one on it.
Be sure to find referrals from at least three happy satisfied customers before making an appointment with an LLMD. You don't want to be wasting ANY time here!
-------------------- --Lymetutu-- Opinions, not medical advice! Posts: 96222 | From Texas | Registered: Feb 2001
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