posted
It is my opinion if a test is IND it means there is enough activity to make it not NEG. There for I believe IND is not a neg but a positive. But with all that aside you tested positive on two CDC bands (which meets criteria for lyme diagnosis based on lab results) on both your IgG and your IgM.
The lyme bands considered byt he CDC are 23-25, 31, 34, 39, and 41. The CDC says if you have two of these showing up than you are positive. I hope you have a llmd,if not get one ASAP!
Below is interpretation of the bands and what they mean:
WESTERN BLOT
9 cross-reactive for Borrellia 12 specific for Bb 18 unknown 20 cross-reactive for Borrellia 21 unknown 22 specific for Bb, probably really the 23/25 band 23-25 outer surface protein C (OspC), specific for Bb 28 unknown 30 unknown; probably an outer surface protein; common in European and one California strain 31 outer surface protein A (OspA), specific for Bb 34 outer surface protein B (OspB); specific for Bb 35 specific for Bb 37 specific for Bb 38 cross-reactive for Bb 39 is a major protein of Bb flagellin; specific for Bb 41 flagellin protein of all spirochetes; this is usually the first to appear after a Bb infection and is specific for all Borrellia 45 cross-reactive for all Borellia (sometimes people with Lyme who have this band positive also have the co-infection Ehrlichiosis) 50 cross-reactive for all Borrellia 55 cross-reactive for all Borrellia 57 cross-reactive for all Borrellia 58 unknown but may be a heat-shock Bb protein 60 cross reactive for all Borrellia 66 cross-reactive for all Borrelia, common in all bacteria 83 specific antigen for the Lyme bacterium, probably a cytoplasmic membrane 93 unknown, probably the same protein in band 83, just migrates differently in some patients
Good luck I hope this helps.........Peace!
-------------------- I'm gonna get that lyme !!! Posts: 61 | From Erie, PA | Registered: Dec 2005
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aI hate to give you the bad news: you have Lyme Disease. 39 kDa is absolutely unique to borreliosis and it you did not have it, it would not be there. Same for 31. Get thee to an LLMD ASAP. TMP
-------------------- Thomas Parkman Posts: 341 | From Columbia SC 29206 | Registered: Feb 2003
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posted
Thanks for the replies everyone - I have indeed seen an LLD although for the moment I have chosen not to take abx as I am assessing alternative approaches.
What I was trying to get a better understanding of was the IND bands and what it means in general to have so many of them.
Thanks for your replies - I always learn so much here.
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