SForsgren
Frequent Contributor (1K+ posts)
Member # 7686
posted
I am interested in anyone that is willing to share their HLA genotype as described in the Rosetta Stone from the Mold Warriors book. I am a 4-3-53 which is Lyme and mold-susceptible. Am very interested in trying to get some idea of how many of us with chronic Lyme have the susceptible gene mutations.
Also I should state that though I believe that these do impact us and our condition, they are not the end all. Gene expressions can be turned on or turned off. I also believe that they represent information which may assist in determining the type of treatment needed (expecially binding agents for folks with primary neurotoxic illness) though may or may not be highly useful if you are already addressing that component of the illness.
-------------------- Be well, Scott Posts: 4617 | From San Jose, CA | Registered: Jul 2005
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posted
Not quite sure how to interpret the HLA except I have the genes for celiac.
DR locus 17,11 DRW locus 52 DQ locus 2, 7
Do you know what this means? I'd love an interpretation. Hiker
-------------------- Hiker53
"God is light. In Him there is no darkness." 1John 1:5 Posts: 10173 | From Illinois | Registered: Aug 2004
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lymemomtooo
Frequent Contributor (1K+ posts)
Member # 5396
posted
Take down, I do not know if all drs can order them or not..One of the mold ghru's tests,is allowed only for his patients..Which I find very frustrating.
I would also guess that many of those with lyme, etc might have the genetic predisposition to make it easier to react to such diseases, thru one of the biotoxin pathways that he describes.. A variety of system like failures or over reactions that can occur...and the domino reaction that follows.
I also think that many of the people that get these things easily, also may have the genetic makeup to not eliminate toxins well..A double whammy..
I am not a Dr and really do not understand everything in the Mold Warriers but so far, my daughter has everything against her.
Also do not beat yourself up about the lyme and pregnancies..Blame the ducks,not yourself. Good luck..
Posts: 2360 | From SE PA | Registered: Mar 2004
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Hi Scott. First thank you for all the help you have given this lyme group and for having such a wonderful website. It is greatly appreciated.
I had a thorough work-up by Dr. S. I have the "dreaded" 4-3-53. I also have 7-2-53, which makes me very suseptible to mold. My MSH is under 8 in two tests. I am on a list of patients to be in his study of MSH if it ever comes to past.
I have a list of all the test he runs and all my results. I also have a "Summary of approach to treatment for biotoxin-associted illnesses. I received his "Mold Warriers" because I am contributing to his research. MSH seems to be a biggee in getting well.
I can try to scan this info and send it to you if I can get the scanner to work. If not, I would be glad to fax or make copies and send it to you.
I seem to have misplaced my copy of Mold Warriers, but he might have his info in that book.
I enjoyed my meeting with him. When he had all the test results, he talked to me on the phone, but I didn't understand a lot of what he said.
Also, he doesn't seem to believe in Lyme Disease. When I gave him my positive tests for Lyme and Babesia, he stated that he doesn't trust the labs. The little I read in his Mold Warriers stated that he doesn't trust the big commercial labs. So, where does that leave our lymies.
I have flunked his Visual Constrat Study several times. I am on my third round of CSM because I am only taking one abx and going thru lymphatic drainage.
Let me know if I can be of further help.
-------------------- tj Posts: 296 | From Portland, OR | Registered: Jun 2003
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SForsgren
Frequent Contributor (1K+ posts)
Member # 7686
posted
Thanks TJ. We share the same genotype! I will contact you via PM.
-------------------- Be well, Scott Posts: 4617 | From San Jose, CA | Registered: Jul 2005
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riversinger
Frequent Contributor (1K+ posts)
Member # 4851
posted
Hi Scott!
My osteopath, and also the doctor's office that I am connected with have tested a LOT of people for the HLA types.
To correct some misconceptions, any doctor's office can order this particular test. It is done through Labcorp. It is commonly done for tissue tying for trnsplant patients. Not a big deal to do, but you do need the Rosetta Stone Scott mentioned to interpret it according to the Mold Warriors criteria.
Some of the other Mold Warriors test ARE difficult to get done, and your doctor has to work with the lab to make sure they are done correctly, but it is possible.
My genetypes are the 15-6-51, which is called Post-Lyme. What that means is my immune system has a hard time recognizing the DEAD Lyme bacteria and clearing it out of the body.
I also have the 1-5 genetype. This one is easil;y damaged in the hypothalamus, and stops producing melanocyte stimulating hormone (MSH). When this happens, you can become vulnerable to any of the biotoxins, because MSH is a major controller of the cytokine cascade. Functionally, it can cause you to become multisuscetible. I am in fact very reactive to mold as well as Lyme, even though I don't have a mold genetype.
My son has the 11-3-52B (multisusceptible) and the 1-5 (low MSH). He has been much less ill than I have, probably because he is younger, and also he has fewer TBD coinfections, but he will have to be careful if the theory is true.
We both have had methicillin resistant Staph in our sinuses, but not the same ones.
In my support group, some people have come up with: Post-Lyme (15-6-51) ten people Multisusceptible (4-3-53) two people Mold (7-2-53) four people Mold (13-3-52A) one Multisusceptible (11-3-52B) two people Mold (17-2-52A) one Low MSH (1-5) three people Multisusceptible (14-5-52B) one
Everyone has had at least one susceptible genetype, some have two. The only people that I have heard that have both genetypes that do not fit into the susceptible categories are spouses of Lymies who got tested just to see. So there ARE some people who aren't susceptible according to this scheme.
The doctors have tested a lot mor ethan this, these are just the ones I could find quickly to respond to your question. We are planning to do a database to see how this all really fits together, but haven't gotten the work done yet.
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