GiGi
Frequent Contributor (5K+ posts)
Member # 259
posted
Water & Salt has been one of the methods I have used for years. The glass container of sole has been sitting on my window sill in the kitchen for years. It never goes empty. Hope you will benefit as we have.
Take care.
Posts: 9834 | From Washington State | Registered: Oct 2000
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Marnie
Frequent Contributor (5K+ posts)
Member # 773
posted
If only it was that easy.
"Acetylcholine produces an influx of sodium through a ligand-gated ion channel."
Acetylcholine (ACh) was first identified in 1914 by Henry Hallett Dale for its actions on heart tissue. It was confirmed as a neurotransmitter by Otto Loewi who initially gave it the name vagusstoff because it was released from the vagus nerve. Both received the 1936 Nobel Prize in Physiology or Medicine for their work.
Later work showed that when acetylcholine binds to acetylcholine receptors on striated muscle fibers, it opens channels in the membrane.
Sodium ions then enter the muscle cell, stimulating muscle contraction.
Acetylcholine is also used in the brain, where it tends to cause excitatory actions. The glands that receive impulses from the parasympathetic part of the autonomic nervous system are also stimulated in the same way.
Acetylcholine is synthesized in certain neurons by the enzyme choline acetyltransferase from the compounds choline and acetyl-CoA.
Organic mercurial compounds have a high affinity for sulfhydryl groups, which attributes to its effect on enzyme dysfunction of choline acetyl transferase.
This inhibition may lead to acetylcholine deficiency, and can have consequences on motor function.
Normally, the enzyme acetylcholinesterase converts acetylcholine into the inactive metabolites choline and acetate.
The devastating effects of nerve agents (in bioterrorism, Sarin gas for example) are due to their inhibition of this enzyme, resulting in continuous stimulation of the muscles, glands and central nervous system.
Certain insecticides are effective because they inhibit this enzyme in insects. On the other hand, since a shortage of acetylcholine in the brain has been associated with Alzheimer's disease, some drugs that inhibit acetylcholinesterase are used in the treatment of that disease.
en.wikipedia.org/wiki/Acetylcholine
Posts: 9481 | From Sunshine State | Registered: Mar 2001
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robi
Frequent Contributor (1K+ posts)
Member # 5547
posted
so .... sole or no sole?
robi
-------------------- Now, since I put reality on the back burner, my days are jam-packed and fun-filled. ..........lily tomlin as 'trudy' Posts: 2503 | From here | Registered: Apr 2004
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