posted
[QUOTE]Originally posted by Virginia of Yore: [QB] Those wanting to try Grapefruit Seed Extract might want to be aware of this 1999 study which found it was the *preservatives* in GSE that seemed to be responsible for the antimicrobial effect. I've used it (a couple of different brands) along with my abx combos--it has been no cure for me.
The grapefruit seed extract that I have doesn't have any preservatives in it. It's the best thing I've ever used to clear up sinus problems.
Kathy
-------------------- You never know how strong you are until being strong is the only choice you have. Posts: 807 | From South Dakota | Registered: Jul 2005
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Sorry I haven't given my report but took me awhile to recover and to be honest...there is so much to tell but I don't have the best brainpower to put it together...
Scientists from Isis Pharmaceutical in CA are developing a revolutionary PCR testing method which will be able to identify an infectious microbe within 6 hours of inserting the sample...
Bb and coinfections are on the hit list.. but this technology is developed primarily for the super bugs like MRSA, and other bad hosp infections...
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"Beta-Lactam Antibodies offer Neuroprotection by Increasing Glutamate Transporter Expression"
Neurologist from John Hopkins. His team focuses mostly on ALS-funded by the NIH. "Glutamate is the principal excitatory neurotranmitter in the nervous system." When synaptic glutamate is not functioning it results in acute and chronic neurological disorders including ALS, stroke , etc...
They used a blinded screen of 1040 approved drugs from all classes to see which if any could affect the expression of GLT1 and its functional activity...it was shocking to them that ceftriaxon or b-lactoms as a class came out on top...
"Ceftriaxone was neuro-protective in vitro when used in ischaemic injury or neruon degeneration...when used in an animal model of ALS, the drug delayed loss of neurons aned muscle strengh and increased mouse survival.
"Thus these studies provide a class of potential neurotherapeutics that act to modulate the expression of glutamate neurotransmitter transporters via gene activation."
(We all guessed this would happen)
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"Laboratory Diagnosis of Lyme Disease in Europe" This Austrian dermatologists discussed how LB is more difficult to diagnosi in Surope because of the heterogenetiy of borrelia sp. comprising seven Osp A serotypes. B. afzelii is the most often detected followed by B. gerinii and Bb sensu stricto.
The German society of microbiology has published guidelines...they also use methods of blood, tissue and other fluid PCR but mostly the EM...
They also use a two tiered system and as far as getting treatment if you don't have a positive test...forget it.
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"Babesia microti Causes Down Regulation of Cytokines and Increased Severity of Lyme Arthritis"
From Kansas, Dept of Dianostic Med/Pathobiology, Vet Medicine...this professor studies mice comparing severity of illness in just Bb or Babesia and Bb...
Significant increases in severity of carditis and arthritis were found in coinfected mice. Also, cytokine levels were measured in lymph nodes and spleen for interferon gamma and tumor necrosis factor ans well as Interleukin 4 and 10...
Also, sig increase of the tumor necrosis factor and reduction in the expression of interleukin 4 seen in coinfected mice. ------------------------------------------- Taking a break be back soon...
-------------------- We are spiritual beings on a human journey...
This Prof. of Neurology did money and mice studies. Basically he found that monkeys are less susceptible to persisitent infection than mice.
"The most important response of mammalian hosts to infection is the production of specific antibody that in the majority of cases clears the infection. The failure of ths antibody response leads to persistant infection, which can lead to tissue injury most notably in the heart."
Other tid bits from him...he works with the NIH...majority of his patient practise if with MS. When asked if he saw LD among his MS pts he said "I am much more likely to see LD that is really MS" (I am not kiddin ya)
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"Medical Hypothesis: Links Between Bb and Dementia"
This awsome pathologist from NY. He was the first investigator in the world to invoke the concept of the "cyst" form for Borrelia based on model pf Treponemal kete cyst form. He was the first investigator to publish images of Bb ketes without corkscrw...
His slides of plaques of alzheimers disease look exactly like plaques seen in syphillis and LD.
His paper "Plaques of Alzheimer's disease originate from cysts of Bb, the Lyme disease spirochete" was published in "medical Hypotheses Vol 67 issue 3 pg592.
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Be back later...time for dinner
-------------------- We are spiritual beings on a human journey...
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The part about monkeys being less susceptible to persistent infection than mice.....
I wonder how they infected those monkeys? It has been noticed that needle infected animals are less likely to get the full force of an infection. This is because tick saliva contains compounds that catalyze the infection process. So, if the monkeys were needle infected from a culture of spirochetes which presumably did not include the saliva, then this could be an explanation for what the researcher observed. Seems it would be premature to say monkeys are less susceptible, especially if they were needle infected.
Posts: 8430 | From Not available | Registered: Oct 2000
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posted
"Cystic Forms and Antimicrobial Therapy" This Microbiologist from Norway had great slides of all the forms of Bb including up to 5 structurally differnet bacteria.
"Blebs arranged as strings of pearls melted together to form thin filamentous structures. Within some cysts, spirochestes appeared to multiply. Core structures within some cysts appeared to produce blebs."
"Cyst formation has also been demonstrated in the presence of antibiotcs, complement, lysozyme, H202 and when exposed to antibiotics, cysts can be induced both in vitro and in vivo. Using silver impregnation and immunochemical staining, cystic material has been demonstrated in every animal and human tissue infected by Bb."
He found that cystic forms were sensitive invitro to metronidazole and tinidazole...also hydroxychloroquine and bismuth in an invivo achievable concentration.
"We are now treating patients with chronic lyme disease with a combination of metronidazole, tinidazole, or hydroxychloroquine in combination with a macrolid or doxycylin. Results are promising."
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"Looking Beyond Lyme: Differential Diagnosis"
This talk was from a prominent chief of ID in NY. He was very good natured about the "camps" and whatnot. Treats a lot of lyme but also works patients up for a million other things...here is a list of what I could write fast enough:
posted
Has anybody tried to crush grapefruit seeds themselvesand put the mush directly onto a plate with bacteria growing in it?
In that way you have the strength of the fresh GSE but not the possible presertvatives that are supposed to preserve the potency of the GSE, but that may also be the only active antibacterial agents in the industial made GSE.
Crushing Grapefruit seeds is not a task requiring great skill.
Maybe the Brorson could do this for us all. They've got the slides with the bugs, the know how, I'll offer to go to Norway to crush the seeds myself if need be (never been to Norway, might like it, if carrying my bag of grapefruits around doesn't get to me after a while:))
Nelly
Note: Grapefruit Seed Extract does not necessarily have the same properties as Grapefruit Juice, etc.
From the rebuttal studies Dave noted, it looks like the Seed has not flowered into a promised treatment.
However...we do not know the purity of the GSE that was used in the research, ie., did the sample contain the preservatives or not?
HUH??? DID IT??? WELL...I am not hearing any answers out there!
Could someone contact the Dr. responsible? I do not know who he or she is, or I sure as H... would.
This was truly a great post...the type we should have here alla da tyme....
Tanks!
Peace, Love and Wellness, JRW [/QB][/QUOTE]
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