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» LymeNet Flash » Questions and Discussion » Medical Questions » My CD57 went up

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Author Topic: My CD57 went up
cantgiveupyet
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In july my CD57 was a 10.

I just got my most recent results and CD57 is a 42.

Im on no abx and the only thing that i did differently is take armour thyroid.

so my llmd says lyme hates heat and now that my temp is up lyme isnt liking it.

its just kinda odd.

--------------------
"Say it straight simple and with a smile."

"Thus the task is, not so much to see what no one has seen yet,
But to think what nobody has thought yet, About what everybody sees."

-Schopenhauer

pos babs, bart, igenex WB igm/igg

Posts: 3156 | From Lyme limbo | Registered: Oct 2005  |  IP: Logged | Report this post to a Moderator
trails
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congrats!
you are still below the norm by quite a long shot but at least a t this point your numbers show you are getting better in the Lyme catagory.
good to hear!

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KENNEDY
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Hi Can't,
I just thought I'd send you a little information I had on the CD57 TEST.
I had started a post on page 4 titled Lyme Test, Again. I wasn't concerned about my Cd57 Test until I got some feed back. Actually I thought it was good. But mine 391 seems off the charts.

KENNEDY
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Member # 9628

[Icon 1] posted 31 October, 2006 08:24 PM [Profile for KENNEDY] [Send New Private Message] [Edit/Delete Post] [Reply With Quote] I brought this topic up again because we kinda touched on it

and some LLMD's don't even do this test Just thought it would be of

interest to some. It was given to me by my first LLMD, it's taken from the,Managing Lyme Disease, 15th edition, Sept, 2005.

The CD-57 Test
Our ability to measure CD-57 counts represents a breakthrough in
LB diagnosis and treatment.

Chronic LB infections are known to suppress the immune system and
can decrease the quantity of the CD-57 subset of the natural killler cells.

As in HIV infection, where abnormally low T-cell counts are routinely used as

a marker of how active that infection is, in LB we can use the degree of

decrease of the CD-57 count to indicate how active the Lyme infection

is and whether, after treatment ends, a relapse is likely to occur.

It can even be used as a simple, inexpensive screening test,

because at this point we believe that only Borrelia will depress the CD-57.

Thus, a sick patient with a high CD-57 is probably ill with something other than Lyme, such as a co-infection.

When this test is run by labcorp( the currently preferred lab, as published studies were based on their assays),

we want our lyme patients to measure above 60; a normal count is above 200.

There generally is some degree of fluctuation of this count over time,

and the number does not progressively increase as treatment proceeds.

Instead, it remains low until the LB infection is controlled, and then it will jump.

If the CD-57 count is not in the normal range when a course of antibiotics is ended, then a relapse willl almost certainly occur.

And I believe this is what trails had said. [[bow]]

Too bad it doesn't say anything about when one's CD-57 is way higher than 200,( like 391 ),

maybe if I keep digging I'll find more on it.

[ 31. October 2006, 11:45 PM: Message edited by: KENNEDY ] Posts: 61 | From: PA. | Registered: Jul 2006 | IP: Logged

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cantgiveupyet
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thanks for posting this info :-)

I do know i am a 'tough case' difficult to figure out.

--------------------
"Say it straight simple and with a smile."

"Thus the task is, not so much to see what no one has seen yet,
But to think what nobody has thought yet, About what everybody sees."

-Schopenhauer

pos babs, bart, igenex WB igm/igg

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johnlyme1
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My LLMD aslo includes a full lymphocite panel to take a look at the other cells as well. My last on was this week. We did one back in may also. My cd57 went from 8% to 15% and I had excelent numbers for the others. CD57 is only part of the view of what your immune system is making to fight the infections. I am still very amazed that my immune system is working as well as it is, wish it was an indicater of feeling better.
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Aniek
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The CD57 appears to be a Lyme specific marker. So it is a good sign if it is going up. Of course, some variation does happen. So it's not a sign of being cured. But be happy about it and that will boost your immune system alone [Smile]

Kennedy -
The article in this post http://flash.lymenet.org/ubb/ultimatebb.php?ubb=get_topic;f=1;t=048915#000000 mentions that a normal range is 60 to 360. So a 391 is definitely above normal.

I don't think you will find anything written anywhere about an above normal CD57. But I think I said before, it was mentioned at the ILADS conference that above 360 might me a sign of autoimmune response.

You may want to ask your doctor to contact the writer of the article in Public Health Alert.

--------------------
"When there is pain, there are no words." - Toni Morrison

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KENNEDY
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Kennedy -

Aniek said:

The article in this post http://flash.lymenet.org/ubb/ultimatebb.php?ubb=get_topic;f=1;t=048915#000000 mentions that a normal range is 60 to 360. So a 391 is definitely above normal.

I don't think you will find anything written anywhere about an above normal CD57. But I think I said before, it was mentioned at the ILADS conference that above 360 might me a sign of autoimmune response.

You may want to ask your doctor to contact the writer of the article in Public Health Alert.

--------------------------------------------------
I plan to talk to my LLMD at my next visit.

It's always something!

Thanks for the info.

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keh
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I had the opposite problem and went from a 74 to a 42. My LLMD told me and I heard from others

that the CD57 fluctuates... with in a day or the same day so I was told that if there was not a big change (like 70 to 200) that it did not mean much..

just an fyi.... but if you are feeling better that is great and probably a good sign !!!!

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cantgiveupyet
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I am feeling better then the day I had the first one done.

Also the 2nd one was done early AM...fasting...

first one mid afternoon, non fasting.


One day all of this will make more sense.

--------------------
"Say it straight simple and with a smile."

"Thus the task is, not so much to see what no one has seen yet,
But to think what nobody has thought yet, About what everybody sees."

-Schopenhauer

pos babs, bart, igenex WB igm/igg

Posts: 3156 | From Lyme limbo | Registered: Oct 2005  |  IP: Logged | Report this post to a Moderator
   

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