posted
Just wondering anyone has take this combo or is currently taking this combo (mino and rifampin). I am starting this in the next day or two and just wanted to find out from others their experience.
Thanks, David
-------------------- Same nightmare, different day! Posts: 401 | From East Coast | Registered: Nov 2005
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NP40
Frequent Contributor (1K+ posts)
Member # 6711
posted
Hi Dave,
This combo should target bartonella and help knock down the lyme load somewhat as well. Any time you switch meds be sure to watch for herx's.
Posts: 1632 | From Northern Wisconsin | Registered: Jan 2005
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Fiance is on this very combo right now. He had been on Rifampin only, which has been helping with some very troublesome skin symptoms that nothing else touched. However, other symptoms (cognitive, neuro) started coming back with a vengeance, so he added the Mino.
The first 2 weeks of Mino were very hard (dizziness, fatigue), the next 2 were up and down, but he is doing very well right now (knock on wood!!!). This seems to be a very good combination for him. He has had some mini-flares, but he is bouncing back from them more quickly than before. I'm more hopeful than I've been in a while.
There are a couple of recent Mino threads that may be helpful, tho' they don't address the 2 meds together.
I know everyone is different, but I hope this is a good combo for you, too. Please keep us posted.
All the best, Aviva
Posts: 532 | From southeast US | Registered: Oct 2005
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posted
Thanks for the info everyone. I already did mino for a month and now I am adding rifampin to the mix. I read that rifampin should be taken away from food but I don't remember that being the case with the minocycline. I guess it's probably best just to take them together about an hour or two away from food. Any thoughts on this?
Viva-what kind of skin symptoms did your fiance have?
Bluetick- I didnt know that about the color changes so thanks for the info!
-------------------- Same nightmare, different day! Posts: 401 | From East Coast | Registered: Nov 2005
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If you're on the Mino already and tolerating it well, that's great.
I'll have to ask about how fiance times the dosing wrt mealtimes.
As far as the skin symptoms: there were really 2 sets. One was stinging bumps that he described as feeling like wasp bites. Sometimes you could practically see one pop up before your eyes. These would create small white bumps that sometimes disappeared quickly, and sometimes stayed for months.
The other was a red rash that started at the site of the (most recent) original bite, and would radiate out to other body parts. It would resolve, and then start again. Don't know the timing of the cycle.
Have you had any skin symptoms? If so, I'd be happy to share what else has helped, along with the Rifampin.
BTW, the bart test he got (Lapcorp or Quest, can't remember) was negative, but the Rifampin has been a big help.
Aviva
Posts: 532 | From southeast US | Registered: Oct 2005
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Jill E.
Frequent Contributor (1K+ posts)
Member # 9121
posted
David,
Like Bluetick said, Rifampin turns the urine - but also all bodily fluids (tears, sweat, stool) orange. I don't wear contact lenses, but apparently it will stain the soft lenses.
Be sure the read the package insert or talk to your pharmacist. Rifampin interacts with all kinds of medications.
The nice pharmacist at my local pharmacy who actually has some knowledge of Lyme and Bartonella told me to reduce my dosage of my seizure med because Rifampin will cause too high a dosage of the other med to go into my system. She said that's because Rifampin affects the liver so much. I need to talk to my doctors about this.
But from what I've read about Rifampin in terms of the package insert and also by doing a google search, it can accelerate the dosage of many other medications.
I just started a low dose of Rifampin so I'm just learning about it too and trying to tolerate it.
Jill
-------------------- If laughter is the best medicine, why hasn't stand-up comedy cured me? Posts: 1773 | From San Diego | Registered: Apr 2006
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posted
I take Rifampin, doxy and bicillin shots. I can't taker the mino as it causes, almost imediately, severe dizziness.
Posts: 547 | From Maryland | Registered: Mar 2005
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posted
Yes, I took Rifampin with Bactrim -- that's a combo favored by Dr. S (author of Mold Warriors). Cleared up a nasal infection within a few days, but the Rifampin made me extremely tired at 75 mg so I didn't stay on it more than a few weeks at a time.
Posts: 47 | From California | Registered: Feb 2006
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Jill E.
Frequent Contributor (1K+ posts)
Member # 9121
posted
quote:Originally posted by imanurse: It's interesting that everyone here is taking Rifampin in combo. I was prescribed Rifampin alone.
I will do some more searching and review Dr. B guidelines. Anybody else take this in combo with anything else?
No, I'm doing it alone for Bartonella, but am also on Bicillin. But since I have to deal with issues of whether my liver can handle medications now, my LLMDs have to be extremely conservative with my treatment.
Jill
-------------------- If laughter is the best medicine, why hasn't stand-up comedy cured me? Posts: 1773 | From San Diego | Registered: Apr 2006
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