Marnie
Frequent Contributor (5K+ posts)
Member # 773
posted
Lyme disease in cats is rare, though cases have been reported. In a limited study, one third of feline blood samples were found to test positive for Lyme disease.
It is probable that some cats are able to resist the illness.
Some owners have described Lyme-infected cats as being in a "zombielike trance". Often, Lyme disease is only diagnosed because the owner notices a tick or a tick bite on the cat; otherwise the symptoms are ambiguous and can be mistaken for other illnesses.
***Studies of cats deliberately infected with Lyme disease showed that some show no symptoms at all!***
Although Lyme disease does not appear to pose a major threat to cats, who
seem more resistant to it than humans or dogs,
its most dangerous feature is that it may go unrecognised and undiagnosed.
Not only do they have less C-acetyltransferase, but...
These results support the conclusion that cytosolic arylamine N-acetylation activity is low in the cat because of the presence of
a ***single N-acetyltransferase***
that has substrate specificity, immunogenicity and sequence characteristics similar to human NAT1, and that the unusual presence of only a single N-acetyltransferase gene appears to be a family wide trait shared by other felids.
PMID: 10022754
Cats have only ONE NAT...HUMANS have NAT1 and NAT2.
And it is not only expressed in the liver, but in our skeletal muscles too:
"In conclusion, the expression of NAT1 in muscle cells may be an important factor in the detoxification/activation processes because of the potential involvement of the muscle in the pharmacokinetics of many xenobiotics (Khazaeinia et al. 2000)."
Now...that brings up another subject...what is the link between olives/catnip and weird behavior in cats...alcohol?
Do cats have less of an ability to process alcohol?
It seems they might:
According to Chicagoland Tails, who cite the Columbia Animal Hospital, alcohol is highly toxic to cats. A tablespoon of whiskey can kill a cat, while just two teaspoons can put the poor thing into a coma.
What is it that makes cats act nuts when they are given catnip OR eat olives?
Why do WE HUMANS eat olives/consume olive oil prior to drinking alcohol to SLOW DOWN drunkeness? Why do almonds do the same? Are the fats and minerals in those foods protective?
When exposed to lyme, do WE have less of an ability to process alcohol?
Chronic ethanol intake resulted in a significant decrease in the rate of rat ponderal growth and an impaired nyctohemeral profile of pineal N-acetyltransferase (NAT) activity.
"Hein et al. suggested that a low n-acetyltransferase 2 activity in the liver and a high nacetyltransferase 1 activity in the prostate contribute to the prostate cancer risk due to heterocyclic amines."
Parkinson's Disease:
The N-acetyltransferase-2 gene (NAT-2) has been associated with Parkinson's disease. The genotype associated with slow acetylation has been reported to be increased in patients with Parkinson's disease.
Sequence variations in N-acetyltransferase 2 (NAT2) gene leading to slow acetylation process have been associated with PD, but results are contradictory.
epidemiological studies have shown that the slow NAT2 acetylator phenotype is associated with increased risk of bladder cancer and may be associated with decreased risk of colorectal cancer.
Now...going back up to one of my first statements...less C-acetyltransferase in their EYES.
Ya all know how cats can see better in the dark and their eyes "glow".
This is why:
"Many animals that hunt at night, including cats, have eyes that appear to glow when a light shines on them.
The glow that you see is light reflected from a mirror-like structure, called the tapetum lucidum, which lines the back of the eye.
Light enters the eye and passes through the retina where special cells, called rods and cones, absorb the light.
Any unabsorbed light hits the tapedum lucidum and is bounced back to the retina where the light
***has another chance at being absorbed.***
Because animals with a tapetum lucidum absorb more light, they can see better in the dark than those lacking the special structure, like humans.
For example, cats can see in about one sixth the light that humans require. The ability to make the most use of any available light is an important advantage for those animals which must catch their next meal at night."
So, cows have 2 stomachs to increase digestion and cats have a special structure in their eyes so that they can ABSORB MORE LIGHT.
We (humans) don't have a tapetum lucidum. People's eyes look red in some photographs, but it's not a reflector. It's the camera flash bouncing off the red blood vessels and red tissue in the back of our eyes.
Different colored irises may account for something. Cats with green or yellow eyes tend to reflect greenish light.
Cats with blue eyes, such as Siamese, tend to reflect reddish light.
Most cats and dogs usually have green eye shine.
Alligators have red eye shine.
Opossums eyes shine pink.
Birdwatchers often refer to the color reaction to a bird's eyes when they have a light shined on them at night, for example, blue eyeshine or green eyeshine.
Most owls have red eyeshine.
At night, wolf spiders can be collected by taking advantage of their eyeshine. The light from a flashlight will reflect off of the tapetum located in the eyes of the spider.
Now what has the color red got to do with all of this?
Energy absorption.
The results show that the minimum light intensity needed
to inhibit or stimulate melatonin levels in both
plasma and the eye
was 6.0 μW/cm2.
A linear correlation was found between the logarithm of light intensity and the relative inhibition.
In addition, the blue wavelength was more effective in decreasing melatonin levels in the former and increasing the levels in the latter.
Nevertheless, red light at sufficient intensity proved effective at
It looks like we'll all be "awake" to see the effects of
global warming.
Bb mutates in response to pH, temperature and CO2 levels...this we know. Goodness knows what other pathogens do to.
They alter their protein coats. Think of what happens when you cook an egg. It changes the proteins.
This is all about balance. We're are disrupting the balance.
Cats may have 9 lives, but we have only one.
If we INHIBIT melatonin via far infrared are we INactivating BOTH NAT enzymes?
Implications?
Or is NAT1 being overproduced and along with it, retinoic acid and are we downregulating that acid via far infrared?
The mention of vitamin D3 (which we know is also being overproduced) makes me wonder.
� Goldman, R., "Induction of a β-1, 3-D-glucan receptor in P388D1 cells treated with
retinoic acid
OR 1, 25-dihydroxyvitamin D3 " Immunology, 63(2):319-324 (1988).
Vitamin D:
Vitamin D Down-Regulates TNFa Expression in Macrophages by Affecting NFkB Activity
With the exception of retinoic acid, the steroid hormones are all derived from cholesterol.
So...rather than breakdown more cholesterol, are we UPregulating retinoic acid?
Does retinoic acid (vitamin A) downregulate necessary vitamin E? It appears both Vitamin A and vitamin E help to preserve our T cells.
If the antibodies are damaged (manufactured and secreted by the B cells) then we are relying solely on the T cells to fight for us.
Time to hit the sheets.
[ 14. January 2007, 12:22 AM: Message edited by: Marnie ]
Posts: 9481 | From Sunshine State | Registered: Mar 2001
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Marnie
Frequent Contributor (5K+ posts)
Member # 773
posted
Up for pq and others really "into" the research.
I edited it to include additional info.
Bottom line for others = far infrared is looking pretty good from more than one angle.
Posts: 9481 | From Sunshine State | Registered: Mar 2001
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quote:Originally posted by Marnie: Bottom line for others = far infrared is looking pretty good from more than one angle.
Thank you so much Marnie for this summary
Often, I feel that your information is very important but I'm too stupid to understand it. It would be great if you always could give such a short bottom line for the brain dead here on board...
Gabrielle
Posts: 767 | From Germany | Registered: Feb 2004
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cantgiveupyet
Frequent Contributor (1K+ posts)
Member # 8165
posted
Good info, I was at the vet a few weeks ago and I asked about my cat getting lyme. he said it was very rare for a cat to even get lyme.
I also had a cat that loved olives, went crazy to get at them...to the point of almost getting his head stuck in the jar if you left the lid off too long. I always wondered about that one.
ahhhh....wish i was a cat. My cat is healthier then me.
-------------------- "Say it straight simple and with a smile."
"Thus the task is, not so much to see what no one has seen yet, But to think what nobody has thought yet, About what everybody sees."
-Schopenhauer
pos babs, bart, igenex WB igm/igg Posts: 3156 | From Lyme limbo | Registered: Oct 2005
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posted
I am really interested in all of this, but can't quite comprehend it. It just took me almost an hour to read that post.. just rereading and rereading, trying to "get it".
I don't get the "cat and the olive" thing.. can someone explain it differently.. or explain any of this stuff in a way that I will be able to understand how it works?
I know you're saying that the infrared is looking good to us, but I love detailed explanation, only, to much detailed explanation, such as the post above, is just over my head. Is frustrating, cuz I want to understand.. help, anyone.
thanks!
Posts: 31 | From US | Registered: Nov 2006
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Truthfinder
Frequent Contributor (1K+ posts)
Member # 8512
posted
Interesting info, Marnie. I didn't get all of it, but some of it. There may be hope for me yet.
Tracy
-------------------- Tracy .... Prayers for the Lyme Community - every day at 6 p.m. Pacific Time and 9 p.m. Eastern Time � just take a few moments to say a prayer wherever you are�. Posts: 2966 | From Colorado | Registered: Dec 2005
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mlkeen
Frequent Contributor (1K+ posts)
Member # 1260
posted
Gee, and I thought cats didn't get lyme because their normal body temp is about 100.2.
I think Lyme does better in cool temps, thus the suspected corrolation between lyme and a lowered body temp in humans, around 97 degrees.
Posts: 1572 | From Pa | Registered: Jun 2001
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CaliforniaLyme
Frequent Contributor (5K+ posts)
Member # 7136
posted
In my experience cats do get Babesiosis really badly- I amd a feral cat rescue advocate/person and have 6 cats. The hunters amoong them tend to get lethargic and start to pine a bit every now & then. I give them 6 droppersful of tonic water a day for 2 weeks and they always return to normal! I am convinced this is Babs!!! Sincerely, Sarah
-------------------- There is no wealth but life. -John Ruskin
All truth goes through 3 stages: first it is ridiculed: then it is violently opposed: finally it is accepted as self evident. - Schopenhauer Posts: 5639 | From Aptos CA USA | Registered: Apr 2005
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quote:Originally posted by gabby: I am really interested in all of this, but can't quite comprehend it. It just took me almost an hour to read that post.. just rereading and rereading, trying to "get it".
I don't get the "cat and the olive" thing.. can someone explain it differently.. or explain any of this stuff in a way that I will be able to understand how it works?
I know you're saying that the infrared is looking good to us, but I love detailed explanation, only, to much detailed explanation, such as the post above, is just over my head. Is frustrating, cuz I want to understand.. help, anyone.
thanks!
What is said up ^ ^ ^ ^ ^there! Please
I have been cold for a long time, chills and cold, that is me, many years, normal temp is 97. I can't even warm up a chair. I got a cold butt.
-------------------- Nov-08 NutraMedix, BurBur Pinella WORKS, Japanese Knotweed, d-Lenolate, ALC, Was on Salt/C 1.5 yrs ended in 06 My brain is working better!!
Feeling very good now Posts: 182 | From Northern, NJ, USA | Registered: Sep 2003
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Marnie
Frequent Contributor (5K+ posts)
Member # 773
posted
Far infrared looks to work on several "levels". I can link, document, what I'm about to say if you need it, but...
Far infrared looks to cause weight loss when done for 20-30 minutes every day (Japanese research). Noticeable results start happening at the 3 month point (which is curious to me...this is when Valletta's patent "kicks in" too.) We start to FEEL BETTER.
Weight loss. Fat goes first, right?
Far infrared looks impact 2 enzymes...amylase (digest sugars) and lipase (digest fats). If we can't TEMPORARILY utilize those enzymes (IF far infrared is "downregulating" them - enzymes are easily destroyed via heat), we THEORETICALLY will knock off Bb who is very dependent on sugars and fats (NOT PROTEINS). For those 20-30 minutes we will perhaps starve Bb and meanwhile we can't use sugar or fat either...just for that short time.
This all has to do with NITROGEN too which is in proteins. Protein builds muscles. More ATP in muscles..more energy, more strength. You men are at an advantage in that respect.
Proteins come from the amino acids and in lyme, we KNOW that there is a significant imbalance happening in certain amino acids...for starters a "tryptophan-tyrosine" defect (imbalance) which according to Reiki research is tied to...ya you guessed it...Mg levels.
Melatonin LOOKS to need nitrogen...as serotonin converting to melatonin uses (2) enzymes...N acetyltransferase is one. Keep in mind, Bb uses C- acetyltransferase.
IF nitrogen is being used up in order to provide the body with the powerful antioxidant - melatonin - then less (theoretically) would be available to combine with oxygen (nitrates -> nitrites -> NO...nitric oxide) to dilate the vessels.
I think NO is being "downregulated". At first it looked the opposite. But now it looks more like the arteries are CONTRACTING, not dilating. This isn't good...longterm. It contributes to less oxygen reaching the teeny tiny vessels at the end...arteries deliver nutrients, but as they do so they sorta get smaller and smaller and smaller until they reach the cells.
We KNOW Bb can be destroyed by the powerful (and damaging) superoxide free radical and NO...nitric oxide. That sneeky bug has found a way to protect itself from both.
It looks also to be able to be knocked off its pedestal by KCL, but it is keeping K out of the cells and Na IN the cells because Na helps transport choline (which we know Bb wants) into the cells...for one.
So IF we downregulate melatonin, and "conserve" nitrogen, will this provide enough nitrogen to ultimately convert to nitric oxide, to dilate our blood vessels...sending nutrients and OXYGEN to the cells...the infected ones?
Another reason why melatonin goes up may be related to our rapidly declining stores of OTHER antioxidants. We KNOW vitamin E drops in lyme. I highly suspect vitamin C does too...esp. since it is linked to zinc and copper levels and we KNOW Bb is impacting/utilizing zinc! (We do not make or store vitamin C).
Lyme disease is causing tremendous "oxidative stress" - way too many free radicals. Most of these are lone oxygen molecules. These do DNA damage...specifically damage the hydrogen bonds that hold our DNA together in a ladder shape. Ideally, oxygen would be combining with hydrogen, but that hydrogen has to get not only into the cell (easy), but then has to get into the POWERHOUSES of the cells. This is where CoQ10 steps in. We make CoQ10 when we ...exercise, I have read. But we need NUTRIENTS TO MAKE IT...B6 (which works with Mg) for starters.
So it appears some enzymes are deficient while others need to be "turned off" (HMG CoA reductase).
I've recently found that the antioxidant, catalase needs help along the way too. I often wondered about that enzyme. It is our most abundant antioxidant enzyme. Where is it? Why isn't it being released to help out? What is holding it back?
It looks like SOD...superoxidase dismutase - anti-oxidant enzyme is hard at work binding Zn and Mn to keep them away from Bb...perhaps. If SOD is too high, it "downregulates" catalase...which is needed to breakdown H2O2 ...hydrogen peroxide...which we are making every split second inside our cells.
This catalase situation looks to do with cell signaling...more later in another post. Call bells aren't working.
A lot of what is happening is related to a "C domain" versus a "N domain". Apparently this is where pyrophosphate's ability to free iron plays a part. Iron carries, binds to, oxygen, but then it has to be RELEASED. It looks like it is not being released. Bb has a protein that binds iron, but also...melatonin looks to bind to it!
Not enough iron...anemic. Less oxygen delivered. This happens too when another enzyme drops...PFK...the enzyme that controls sugar utilization.
In some ways this iron binding is protective. Many other pathogens use iron to multiply (Bb doesn't), so the body goes into a "make iron less available" mode to prevent co-infections.
Bb has/is using C-acetyltransferase. This enzyme is needed to make acetylcholine.
To "balance" acetylcholine...norepinephrine goes up. It comes from dopamine...dopamine -> norepinephrine -> epinephrine (also called adrenaline) -> cortisol + oxytocin.
Cortisol? OOPS. Not good. We KNOW steroids such as cortisone make this disease WORSE.
It looks like far infrared maybe increasing NO production...dilating the blood vessels.
It looks like Ginkgo also helps dilate blood vessels in the brain. Viagra dilates them elsewhere. Nitroglycerine dilates the cardiac vessels(and brain = migraines after nitroglycerine sometimes) too.
Lactic acid, which we make when we EXERCISE looks to also dilate the vessels. TOO MUCH EXERCISE (marathons) isn't good because excessive exercise increases CORTISOL.
To counter...at a certain point...runners' "high"...as the "feel good" hormones are released, right? These are the endorphins that we make and store at exactly 2am every night. It never varies.
But we must be able to dilate the vessels (arteries) in order to send nutrients to the cells (including oxygen!) to stay healthy.
Which is why it is imperative we KEEP MOVING. Get some exercise...not a lot...but some...every day. Take walks. Get/keep the blood flowing.
You are probably suffering from information overload.
The body is so complex and so much is happening simultaneously it is hard to say this happens first then this.
Just keep trying to understand it. Read things over and over and I guarantee you will begin to see how these puzzle pieces all "fit together".
Do not expect you will catch on fast. It takes all of us, under the best circumstances, 7 times to learn something...7 repetitions before it is committed to memory and stored (filed away) as we sleep...when we produce melatonin! We make MEMORIES when melatonin goes up.
It is funny, but as we age, we make less melatonin, but sure as heck are able to pull old memories out of "storage".
Amazing, isn't it?!
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