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» LymeNet Flash » Questions and Discussion » Medical Questions » What's best for balancing Th1 & Th2 & inflamamtion?

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Author Topic: What's best for balancing Th1 & Th2 & inflamamtion?
thelymelight
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Member # 4354

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I have chronic lyme & babesia for over 18 years now and seem to be stuck in my recovery..My dr. says I need to get on something to balance out the Th1 & Th2 part of the immune system and bring down the systemic inflammation.

He is recommending Low Dose Naltrexone for this, but to take it he wants me to go off my antidepressant....I really don't want to start messing about, with coming off the anti-depressants..and would rather find something else instead.

I have read that taking Heparin or Transfer Factor can help accomplish this...

Has anyone had success using either of these products for the above problems, or can anyonoe recommend something else that has worked for them?

Thanks,
Lisa

Posts: 58 | From Ontario, CANADA | Registered: Aug 2003  |  IP: Logged | Report this post to a Moderator
lou
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Does he want you to go off the antidepressant because it might have an interaction, or for another reason?

The drug he is suggesting ought to be tried by some lymies, because inflammation might be part of the chronic problem. Whether you are the right one to try, I don't know.

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Marnie
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TNF alpha and IL1 Beta look to be the body's chosen route to fighting Bb (for multiple reasons!!!) since many of the antibodies we make to destroy Bb are damaged (fab portion - due to Mg deficiency...ongoing).

Okay...still too much inflammation ongoing isn't good either!!!


Here are some ideas:

If you chose to lower the level of lactic acid:

"Reduced plasma levels of lactic acid levels
following L-carnitine treatment may be related with both improved insulin resistance and increased oxidative glucose use by

activating pyruvate dehydrogenase

and decraesing intra mithochondrial Acetyl CoA / CoA ratio.

L-carnitine promotes mitochondrial beta oxidation of long-chain fatty acids by facilitating their transfer across the inner mitochondrial membrane."

(L-carnitine helps Omega 3s - the balance of the Omega 6s and 3s is off, once again...protective in a sense, but too much is destructive.)

http://www.turk-jem.dergisi.org/pdf.php3?id=481


Omega 3s .

Selenium in pharmacological doses...lowers TNF alpha...with:

Gamma E by Jarrow Formulas. "Alpha" is the anti-inflammatory, "gamma" appears to be the anti-oxidant (which is really needed! because way too many damaging free oxygen radicals are happening).

Mg with a B complex . Mg is an "anti- histamine" and anti-inflammatory. PERSONALLY, I often take 400mg of Mg citrate and a B50 complex at bedtime (I don't have lyme, a relative did...now "autoimmune")

CoQ10 .

SOD by Solaray contains all the anti-oxidant ENZYMES.

Green Tea decaf.

Vitamin C (small, kid's doses, more often)

Good old ASA (aspirin)...just a little. Bufferin contains Mg with ASA.

Gluco Reg by Solaray. It is chromium + acids.

Ginkgo if you can tolerate.

Consider one of the other PDE4 inhibitors we have been discussing. Personally, I'd try lactoferrin first.

I'm not going to make friends with this, but...

Honey and REAL Maple syrup . Look very, very closely at what nutrients IN BALANCE are in those NATURAL foods. If you want, I will pull up and post the files.

Keep in mind, our defense system, our WBCs, NEED GLYCOGEN too...as well as our brain cells! Post op...blood sugar levels go UP to help us to heal. We MUST have some glycogen. Just try not to stimulate an insulin SPIKE by scooping that "white processed unnatural sugar" in a drink!

When "sugar" (glycogen, positive charge)in a food is in balance with vitamins (acidic, negative charge) this does not trigger acidic insulin release.

Sugar ALONE (positive charge) triggers (acidic, negative charge) insulin release.

Sorta makes sense, right?

The combo...little sugar OR a little mineral + LOTS of acids (vitamins, amino acids) = hydrogen.

That's our pH...potential of hydrogen... to serve as our energy source.

I watched (in shock) as a patient literally POURED honey into tea.

On the internet, I read where someone actually cured a yeast infection by drinking LOTS (!) of REAL purple grape juice.

It is the combination...sugar + tannins (tannic acid). The tannins (dark colors...grapes, blueberries, raspberries, etc.) are really powerful.

I believe we crave what we need.

"Listen" to your body.

There is a LOT of truth to a nice cup of tea with honey and lemon (esp. limonene!). Our grandparents knew it.

An apple a day for the BALANCED nutrients as well as the pectin.

Get in a "coolish" (about 80+ degrees) swimming pool daily for several minutes. Do some gentle exercises while in the pool. Water therapy is really good.

You know...cold to reduce swelling/inflammation, right?

Be sure to rinse off the chlorine.

Here are some links to healthy food choices/antioxidants:

http://www.naturalhealthtechniques.com/Diet_Nutrition/antioxidant_list_&_foods.htm

http://www.1stvitality.co.uk/az/antioxidants/antioxidants.htm

http://www.findarticles.com/p/articles/mi_m0FKA/is_10_66/ai_n6200695

http://www.vegparadise.com/news45.html

TNF alpha generates additional oxidative stress.

A Mg deficiency is KNOWN to cause oxidative stress.

A DECREASE in PFK -> anemia. NORMALLY Mg-ATP controls PFK. So can citrates and a few other things.

This happens to our astronauts too. When they return to earth they have lower PFK levels and are anemic. I've linked that before (Skylab research.)

Bb is PFK dependent. This is the "rate limiting" enzyme for glycolysis.

Bb has a "sweet tooth". Bigtime.

You must have some carbs. Complex carbs are okay. They do NOT trigger an insulin spike and ACTIVATE PFK.

Think: "Italian". Spaghetti, tomato sauce, olive oil...

I am not a doctor. Just someone who has been doing a TON of research for years, trying hard to figure out WHY longterm nonstop abx. didn't clear this infection and -> "autoimmune".

NO STEROIDS...ever!

Good luck.

Posts: 9481 | From Sunshine State | Registered: Mar 2001  |  IP: Logged | Report this post to a Moderator
   

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