posted
Just really felt the need to put this out there and get some feedback. I'm sure you guys are sick of test results, but it *feels* important, even if it isn't.
I'm on abx (two weeks) every other day now (100 of Minocycline). Should I be retested in two weeks or go off abx and then be retested? So confusing.
IGG: IND on 41 ++ on 45 + on 58 All others negative
IGM: IND on 31, 34, 39 and 41 + on 66 All others negative
Babesiosis and Bartonella are negative on all screenings. Erlichea results aren't back yet.
So I'm IND on the two most lyme-specific bands. That means there were antibodies present, right? Just not enough to make a big fat positive? Or am I confused about that, too?
Also, what is 45 specific for? Looks like I have *that*, whatever it is.
Thanks for taking the time to pacify this newbie!
Sarah
Posts: 91 | From East TN | Registered: Mar 2007
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posted
Yes, IND means they saw SOMETHING....it's just a weak positive. In my book, you definitely have Lyme...but I'm not a dr!
There is no need to be retested unless you want to. Ask your dr about it. Your test clearly indicates Lyme since you have lyme specific bands, like 39.
22: Possibly a variant of outer surface protein C.
23-25: Outer surface protein C (osp C).
28: An outer surface protein.
30: Possibly a variant of outer surface protein A.
31: Outer surface protein A (osp A). 34: Outer surface protein B (osp B).
37: Unknown, but it is in the medical literature that it is a borrelia-associated antibody. Other labs consider it significant.
39: Unknown what this antigen is, but based on research at the National Institute of Health (NIH), other Borrelia (such as Borrelia recurrentis that causes relapsing fever), do not even have the genetics to code for the 39 kDa antigen, much less produce it. It is the most specific antibody for borreliosis of all.
41: Flagella or tail. This is how Borrelia burgdorferi moves around, by moving the flagella. Many bacteria have flagella. This is the most common borreliosis antibody.
45: Heat shock protein. This helps the bacteria survive fever. The only bacteria in the world that does not have heat shock proteins is Treponema pallidum, the cause of syphilis.
58: Heat shock protein.
66: Heat shock protein. This is the second most common borrelia antibody.
73: Heat shock protein.
83: This is the DNA or genetic material of Borrelia burgdorferi. It is the same thing as the 93, based upon the medical literature. But laboratories vary in assigning significance to the 83 versus the 93.
93: The DNA or genetic material of Borrelia burgdorferi.
"In my clinical experience, if a patient has symptoms suspicious for borreliosis, and has one or more of the following bands, there is a very high probability the patient has borreliosis. The significant antibodies, in my opinion, are the 18, 23-25, 28, 30, 31, 34, 39, 58, 66 and 93."
[Dr C of MO]
-------------------- --Lymetutu-- Opinions, not medical advice! Posts: 96222 | From Texas | Registered: Feb 2001
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