Marnie
Frequent Contributor (5K+ posts)
Member # 773
posted
"A great deal of evidence suggests that lymphocytes (WBC) can be a source of prolactin as well..."
"The prolactin molecule is arranged in a single chain of amino acids with three intramolecular disulfide bonds between
six cysteine residues
(Cys4-Cys11, Cys58-Cys174, and Cys191-Cys199 in humans)"
Bb's "zinc fingers" are made of cysteine and histidine bound to zinc.
My question:
Does prolactin from WBCs, if broken down, provide cysteine to promote the development of Bb's zinc fingers?
"Interestingly, some researchers[26,27] have reported that plasma prolactin levels decrease after a full-term pregnancy and that each additional child adds to the long-term and permanent decrease in prolactin.
Could this explain the observation that women who have early and multiple pregnancies seem to be at lower risk for breast cancer?
Zumoff,[3]who reviewed numerous studies that documented elevated levels of prolactin in women who have breast cancer, concluded that
low levels of prolactin may be protective against breast cancer,
but excess prolactin does not necessarily increase the risk."
However...others say:
"Our results point to lower levels of prolactin and, perhaps, higher levels of estradiol as contributing to or correlating with the occurrence of nausea with or without vomiting at any time during the pregnancy until the 27th gestational week.
We found no evidence that estriol, progesterone, or sex hormone-binding globulin is associated with this condition."
But...
"Also, there is suggestive evidence that extreme nausea during the pregnancy may be related to risk of breast cancer in the daughter."
Due to higher levels of estradiol?
Cortisol connections? HPA axis off because not enough serine is phosphorylized ?
Serine deficient...can come from glycine...which we know Bb is using...
Geeze Louise! Too much interplay...neurotransmitters, neurohormones...
[ 02. July 2007, 08:50 AM: Message edited by: Marnie ]
Posts: 9430 | From Sunshine State | Registered: Mar 2001
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posted
have you had any luck treating your lyme, or has it just felt like an endless wild goose chase?
Posts: 244 | From Ottawa | Registered: Dec 2005
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Marnie
Frequent Contributor (5K+ posts)
Member # 773
posted
I do not have lyme, my sister does. She was misdx'd and given steriods initially...disastrous.
She choses to go the "traditional" route...for 3 years nonstop abx. including IV Rocephin and a TON of supplements (following Dr. B's suggestions).
Now is dx'd "autoimmune" and was on all those drugs.
Now off all except highest level of anti-depressant.
Better? If so...I wouldn't still be here...and still researching to try to put the puzzle pieces together.
This is a very, very complex pathogen that is impacting a LOT of nutrients...which are needed to make our proteins in order to fight.
This pathogen triggers us to provide it with exactly what it needs. NaCl for motility and an ongoing supply of glucose...for starters.
Very clever!
Posts: 9430 | From Sunshine State | Registered: Mar 2001
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