Clinically, it is not uncommon to have a patient complain that an area of an old injury or old infection becomes symptomatic when he becomes ill subsequently with some other condition.
Antibodies, formed by matching slightly altered self-molecules, slightly altered by the previous injury or infection, were at the time of the original insult suppressed as the original inflammation resolved.
There have been described multiple mechanisms of immunoregulation in immunology texts whereby antibody reactions are brought under control.
I hypothesize that an additional mechanism of suppression is that as the normal relatively reduced redox potential of the tissues is restored, the antibodies become reduced and unprimed.
Subsequently, when the patient's free radical scavenging mechanisms are overwhelmed by some different condition, the redox potential in the body systemically becomes more oxidizing and old antibodies begin to seek matches.
Some antibodies generated during the previous insult may then match those previously affected areas and result in pain and inflammation.
Additionally, those antibodies may cross react with tissues similar to the previously affected tissues and more generalized conditions such as arthritis, myositis, tendonitis, neuritis, etc. may result.
Foreign body molecules, especially from foods and chemicals, similarly may multiply antibodies which cross react with self-molecules.
Ascorbate is frequently extremely effective in averting this situation because the systemic redox potential is kept relatively reducing despite local pathological processes generating considerable quantities of free radicals.
Sometimes fully developed autoimmune reactions can be markedly ameliorated by massive doses of ascorbate by driving reducing redox potentials directly into the depths of the autoimmune reactions.
Quite frequently, if high levels of ascorbate are maintained such that the autoimmune response is mostly but not completely blocked, the reaction may become intermittent and reveal itself to be related to some previously unsuspected antigen and not be a true autoimmune reaction after all.
In patients suspected of having food and chemical sensitivities, it may be difficult to determine by history which foods and chemicals are causing reactions because the reactions last for days.
Frequently, the duration of these reactions are shortened by large doses of ascorbate sufficiently that the cause of the reactions become more obvious.
Posts: 294 | From nevada | Registered: Sep 2005
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tailz
Unregistered
posted
I've noticed this, too.
I've had equivocal antistriatal muscle antibodies. Interesting.
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butchieboo
Unregistered
posted
I thought that pain was experienced because of the inflamation which causes tissue to put pressure on surrounding nerves.
What type of doctor are you, if you don't mind my asking?
We rarely have the honor of a real doctor visiting or contributing scientific information around this place.
klutzo
Frequent Contributor (1K+ posts)
Member # 5701
posted
butchieboo, If you click on the blue link with his name, you will find the author is a doctor of orthomolecular medicine. You will also find an article detailing this further.
I am not sure I am buying this. I am very toxic, with the most severe pollen allergies and the most severe MCS of anyone I've ever known or heard of, yet I can't tolerate more than 500 mgs. of vit. C daily without getting diarrhea. In fact, I take one gram to get things going if I have the opposite problem.
Klutzo
Posts: 1269 | From Clearwater, Florida, USA | Registered: May 2004
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butchieboo
Unregistered
posted
I see Klutzo,
There seems to be a recent rush to the boards lately to put so many words, especially polysyllabic medical or scientific sounding words.
Is there some kind of bill or something getting ready to be voted on in the House or Senate?
That usually brings out the most litterally prolific contributors to the boards here.
I have been hearing about Vitamin C...massive doses, ever since that doctor in Germany used it, to cure cancer...
quote:Originally posted by butchieboo: I see Klutzo,
There seems to be a recent rush to the boards lately to put so many words, especially polysyllabic medical or scientific sounding words.
Is there some kind of bill or something getting ready to be voted on in the House or Senate?
That usually brings out the most litterally prolific contributors to the boards here.
I have been hearing about Vitamin C...massive doses, ever since that doctor in Germany used it, to cure cancer...
what was that? Approximately 15 Years ago?
BB
That's rich! I needed a good laugh.
Just posting it as a resource. Take it or leave it.
I am amazed at how some will try a certain this or that, and get a less than desirous result i.e. diarrhea, and immediately stop.
Klutzo, how about trying a lower dose that does not give you the runs, and then over time work your way up. Actually I think that is what this Dr. advocates, more or less.
All in good time.
I am still learning.
Posts: 294 | From nevada | Registered: Sep 2005
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posted
Actually, Dr. C., I appreciated this post. I've often wondered about the mechanism for the increase in pain at sites of tissue trauma, when other infections/maladies are encountered by the body.
The writer, Norman Cousins, recovered from a severe illness with massive quantities of IV Vitamin C. If I remember right, it was a special kind of C and he was under the care of an open-minded physician.
Thanks for your post.
Posts: 422 | From Luck home | Registered: Sep 2005
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Foggy
Frequent Contributor (1K+ posts)
Member # 1584
posted
ART address this, epecially with scars. Take it GiGi, Scott...
Posts: 2451 | From Lyme Central | Registered: Aug 2001
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That's rich! I needed a good laugh.
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