LymeNet Flash: Abx. that is also an anti-anxiety!

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»	LymeNet Flash » Questions and Discussion » Medical Questions » Abx. that is also an anti-anxiety!

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Topic: Abx. that is also an anti-anxiety!

Marnie
Frequent Contributor (5K+ posts)
Member # 773

posted

D-cycloserine.

To see the implications...go to the following and read my 5:30am post.

http://flash.lymenet.org/ubb/ultimatebb.php?ubb=get_topic;f=1;t=056568

Keep in mind...TB forms cysts too and takes months to years to treat.

But higher doses look to be increasingly beneficial.

Posts: 9481 | From Sunshine State | Registered: Mar 2001 | IP: Logged |

tailz
Unregistered

posted

I'm lost. Can you draw some stick figures?

I just know I need to find me a lizard - and fast;)

IP: Logged |

Marnie
Frequent Contributor (5K+ posts)
Member # 773

posted

I think that is IT! The abx. D-cycloserine. For MANY reasons .

IF you are looking at a "traditional" route.

Is that clear?

Keep in mind...when dealing with cyst forms of pathogens we're looking at many MONTHS if not a few years to CLEAR the infection...as with TB.

The right dosage looks to be important.

Posts: 9481 | From Sunshine State | Registered: Mar 2001 | IP: Logged |

danielb
LymeNet Contributor
Member # 8522

posted

antibiotic dosages have been known to be capable of causing serious depression and CNS toxic side effects. i remember lower dosages, related to its affinity for the glycine NMDA site, being looked at for psychiatric uses. presumably, high dosages are possibly too much, and are excitotoxic or near.

Posts: 244 | From Ottawa | Registered: Dec 2005 | IP: Logged |

Marnie
Frequent Contributor (5K+ posts)
Member # 773

posted

A quick search:

D-cycloserine, an antibiotic, relieves chronic neuropathic pain

D-cycloserine is an antibiotic which is

used in the treatment of tuberculosis.

It is sold by Eli Lilly under the brand name Seromycin.

Apart from its antiboitic activity,

the drug also has effects in the brain, and has been found to be effective in helping people to overcome phobias, and to help children with autism to improve their social

and communication skills.

A recent study in rats with neuropathic pain has shown that after taking D-cycloserine daily for two weeks, they were substantially less sensitive to touch in the painful areas.

The greater the dose, the greater the reduction in sensitivity. The drug did not appear to affect the normal pain sensations in areas of the body without neuropathic pain.

Although it's painkilling properties have so far only been tested in rats, three features of this drug are particularly encouraging:

The drug is already approved, and so can be prescribed by a doctor

The drug can be taken by mouth, and doesn't need to be injected

Papers about other uses of the drug say that it is generally well tolerated, without serious side-effects in most people.

http://www.coccyx.org/treatmen/cycloser.htm

CONCLUSIONS: In this pilot study, D-cycloserine treatment resulted in significant *improvement* in social withdrawal. Further controlled studies of D-cycloserine in autism appear warranted.

PMID: 15514414

Posts: 9481 | From Sunshine State | Registered: Mar 2001 | IP: Logged |

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