CaliforniaLyme
Frequent Contributor (5K+ posts)
Member # 7136
posted
COULD be- and don't panic re the dog abstract because this human worst case scenario- it turned out- EXCELLENTLY!*)*!)! Because they don't bother doing dialysis for dogs- and the person got OFF dialysis- so even WORST CASE SCENARIO is great-
I have had recurrent kidney stuff my whole life because of a birth defect- kidney stuff can be scary- hugs to you- Best wishes, Sarah ****************************************
1: Am J Kidney Dis. 2004 Mar;43(3):544-51.
MPGN secondary to Lyme disease.
Kirmizis D, Efstratiadis G, Economidou D, Diza-Mataftsi E, Leontsini M, Memmos D. University Department of Nephrology, Hippokration General Hospital, Thessaloniki, Greece. [email protected]
Lyme disease is a multisystem disorder with protean clinical manifestations that is caused by the tick-transmitted spirochete Borrelia burgdorferi.
Infection caused by B burgdorferi is known to induce glomerulonephritis in animals.
We report a patient with acute postinfection membranoproliferative glomerulonephritis after the clinical multisystem manifestation of Lyme disease, which was confirmed serologically.
Although the patient was dialysis dependent for a protracted period of 5 months, the final outcome was excellent.
PMID: 14981613
1: Vet Pathol. 1997 Mar;34(2):85-96. Links
Morphologic, immunohistochemical, and ultrastructural characterization of a distinctive renal lesion in dogs putatively associated with Borrelia burgdorferi infection: 49 cases (1987-1992).
Dambach DM, Smith CA, Lewis RM, Van Winkle TJ. Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, USA.
A distinctive renal lesion consisting of glomerulonephritis, diffuse tubular necrosis with regeneration, and interstitial inflammation was found in 49 biopsy/necropsy cases obtained from 1987 to 1992.
This lesion is manifested clinically as a rapidly progressive glomerular disease that was uniformly fatal.
Immune-mediated membranoproliferative glomerulonephritis predominated (43/49, 88%). Membranous glomerulonephritis (5/49, 10%) and amyloidosis (1/49, 2%) were also noted.
Subendothelial deposits, IgG, IgM, and C3 were present along glomerular basement membranes. IgA was absent.
The exact cause of the tubular necrosis is unknown. Affected dogs were significantly younger than dogs with other forms of glomerulonephritis and amyloidosis both in the studied population for the same period and in the reported canine population. Labrador and Golden retrievers were 6.4 and 4.9 times more likely, respectively, to develop this lesion.
This is the first report of a breed predilection for spontaneous canine glomerulonephritis.
Previous reports have associated this lesion with Borrelia burgdorferi exposure. All dogs in this study were from Lyme disease-endemic areas.
Of 18 dogs serologically tested, all were positive for exposure. Silver stain examination of kidneys revealed rare spirochetes, suggesting that the presence of spirochetes in the kidney is apparently unrelated to lesion development. The role of vaccination in development of the renal lesion is undetermined.
The association of this histologically and clinically unique lesion, Lyme nephritis, with Borrelia burgdorferi infection is significant because it is the only fatal form of canine Lyme borreliosis.
PMID: 9066075
1: Ir Med J. 1999 Aug;92(5):372.Links Lyme disease and glomerulonephritis.Kelly B, Finnegan P, Cormican M, Callaghan J. Dept. of Medicine, University College Hospital, Galway.
PMID
-------------------- There is no wealth but life. -John Ruskin
All truth goes through 3 stages: first it is ridiculed: then it is violently opposed: finally it is accepted as self evident. - Schopenhauer Posts: 5639 | From Aptos CA USA | Registered: Apr 2005
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CaliforniaLyme
Frequent Contributor (5K+ posts)
Member # 7136
posted
p.s. Last time I had a kidney thing they treated it with IV Rocephin!*)!!! So you may get that! I know it is scary, but hang in there- worst case scenario I could find for you re Bb related ended up EXCELLENT- remember that*)!!! Take care- Best wishes, Sarah
-------------------- There is no wealth but life. -John Ruskin
All truth goes through 3 stages: first it is ridiculed: then it is violently opposed: finally it is accepted as self evident. - Schopenhauer Posts: 5639 | From Aptos CA USA | Registered: Apr 2005
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quote:Originally posted by Julie4848: I was told the same thing years ago, I have two simple cysts on my left kidney. They leave them alone and just watch them...
That would be good news for merrygirl!!
-------------------- --Lymetutu-- Opinions, not medical advice! Posts: 96222 | From Texas | Registered: Feb 2001
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posted
I'm sorry to hear this. I will keep you in my thoughts about this!
I'm so thankful that you are heading to CT and a world class LLMD!!!!
Allie
Posts: 300 | From Northeast | Registered: Dec 2006
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TheCrimeOfLyme
Frequent Contributor (1K+ posts)
Member # 4019
posted
I have a tumor in the left lower pole of my kidney. I know that this issue runs in my family, but I tested genetically negative for that issue.
I would have to say lyme could do this. My daughter has lyme and TONS of kidney problems, BUT she was born with a birth defect. Still, lyme knows no boundaries, organs included.
-------------------- You want your life back? Take it. Posts: 3169 | From Greensburg, Pennsylvania | Registered: Jun 2003
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