LymeNet Flash: grapefruit juice

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»	LymeNet Flash » Questions and Discussion » Medical Questions » grapefruit juice

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Author

Topic: grapefruit juice

sal66
Member
Member # 13223

posted

I have no idea about the extract, but I've read that grapefruit juice is bad to take with alot of medications. Or at least some pain medicines. Anyone have any more info about this?
Another Question: Is anyone taking Lyrica? Please send me comments about it.
Thanks

Posts: 30 | From enfield,ct | Registered: Sep 2007 | IP: Logged |

Looking
LymeNet Contributor
Member # 13600

posted

You can find patient experiences with Lyrica here:

http://www.askapatient.com/viewrating.asp?drug=21723&name=LYRICA
*******

Do not take grapefruit juice if you are taking terfenadine (seldane) or astemizole (Hismanal) due to the possibility of fatal cardiac arrhythmias.

Basically, grapefruit juice can intensify drug potency and as a result also the side effects of certain drugs. Grapefruit juice also can interfere with the metabolism of certain drugs and the unmetabolized drugs can be toxic causing serious reactions.

Medications That are Affected by Grapefruit Juice Use (There may be others):

Statins (Cholesterol Lowering Drugs):
Baycol (Cerivastatin)
Mevacor (Lovastatin)
Lipitor (Atorvastatin)
Zocor (Simvastatin)

Antihistamines:
Ebastine
Seldane (Terfenadine, taken off the U.S. market)

Calcium Channel Blockers (Blood Pressure Drugs):
Nimotop (Nimodipine)
Nitrendipine
Plendil (Felodipine)
Pranidipine
Sular (Nisoldipine)

Psychiatric Medications:
Buspar (Buspirone)
Halcion (Triazolam)
Tegretol (Carbamazepine)
Valium (Diazepam)
Versed (Midazolam)

Intestinal Medications:
Propulsid (Cisapride, taken off the U.S. market)

Immune Suppressants:
Neoral (Cyclosporine)
Prograf (Tacrolimus)

Pain Medications:
Methadone

Impotence Drug:
Viagra (Sildenafil)

Miscellaneous

Losartan (for lowering blood pressure) - Grapefruit juice inhibits the body's ability to absorb the drug.
Digoxin (for treating congestive heart failure) - Grapefruit juice inhibits the body's ability to absorb the drug.

Looking

Posts: 590 | From Canada | Registered: Oct 2007 | IP: Logged |

hiker53
Moderator
Member # 6046

posted

A pharmacist would be a great source of information to know if grapefruit interacts with Lyrica or other drugs. Hiker53

--------------------
Hiker53

"God is light. In Him there is no
darkness." 1John 1:5

Posts: 10174 | From Illinois | Registered: Aug 2004 | IP: Logged |

Aniek
Frequent Contributor (1K+ posts)
Member # 5374

posted

Grapefruit juice impacts the metabolism of certain drugs that are supposed to be extended release so the entire amount of medication enters your system at once. That leads to an overdose.

I decided to just stay away from grapefruit and grapefruit juice because I take a number of supplements and meds. It's easier to stay away from that one food than check everything for an interaction.

--------------------
"When there is pain, there are no words." - Toni Morrison

Posts: 4711 | From Washington, DC | Registered: Mar 2004 | IP: Logged |

Walnut
LymeNet Contributor
Member # 6585

posted

Never drink grape fruit juice with mepron.

Posts: 187 | From Washington, DC | Registered: Dec 2004 | IP: Logged |

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