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» LymeNet Flash » Questions and Discussion » Medical Questions » Kidney Damage from Antiobiotics? HELP ME...

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Author Topic: Kidney Damage from Antiobiotics? HELP ME...
MisterGreen
Junior Member
Member # 13996

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I have a question.

When I started abx I was very depressed and drank heavily for a period of a year.

No, not every day-but weekend binge drinking. Mostly whisky.

At the same time was on doxy-azithro cocktail of high mil.

There is something also going around about gladolinium contrast being bad news.

Over the past 2 years I have had 6 MRIs with GAD.

I have developed pain in my kidneys.

HELP!

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Our condition indeed has made our lives difficult.

Posts: 9 | From Washington State | Registered: Dec 2007  |  IP: Logged | Report this post to a Moderator
pingpong
LymeNet Contributor
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i recall having read a newpaper article mmonths ago, mentioning gadolinium contrast and heart and kidneys.

try starledger.com
google pub med. and search there.

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pingpong

Posts: 361 | From At the Pingpong Tournament | Registered: Oct 2007  |  IP: Logged | Report this post to a Moderator
MisterGreen
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thanks pingpong for taking the time over these holidays to check it out.

I will look.

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Our condition indeed has made our lives difficult.

Posts: 9 | From Washington State | Registered: Dec 2007  |  IP: Logged | Report this post to a Moderator
feelfit
Frequent Contributor (1K+ posts)
Member # 12770

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Gadolinium in contraindicated as a contrasting agent in those w/ kidney impairment. There are several lawsuits that have stemmed out of the use of Gadolinium in those w/ kidney problems.

If you think that you have kidney problems, better get it checked out.

Best,
Rhonda

Posts: 3975 | From usa | Registered: Aug 2007  |  IP: Logged | Report this post to a Moderator
Keebler
Honored Contributor (25K+ posts)
Member # 12673

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-

www.fda.gov/Cder/drug/advisory/gadolinium_agents.htm

Public Health Advisory_ Gadolinium-containing Contrast Agents for Magnetic Resonance Imaging (MRI): _ Omniscan, OptiMARK, Magnevist, ProHance, and MultiHance

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Also see: www.fda.gov/cder/drug/infopage/gcca/default.htm

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Your topic question is: kidney damage from antibiotics.

Even if there is damage, there is no way to determine if the source of that damage is from meds as alcohol mixing with meds changes everything the meds were intended to do.

I would also think there would be no way to know if the Gadolinium caused any damage in the presence of alcohol which alone and, especially, with Rx is very toxic and damaging to the entire body. I really don't mean to preach here as we all do the best we can to get by.

If alcohol is still in your "meal plan" you might have a serious talk with your doctor about that. It is important - and fair - that the doctor know before prescribing any medicines. It changes everything - totally. And it puts you and that doctor's practice at risk.

The doctor also needs to know about past use so they can have a clear and honest picture regarding the direction of you progress.

I hope the pain subsides and all works out okay for your best health in the New Year.

If you have to have the contrasting agent for a test, perhaps there is a way to immediately - and gently - flush it from your system. I'd ask an expert on that though. Most MDs would never consider it important, but some might.

-

[ 30. December 2007, 06:31 PM: Message edited by: Keebler ]

Posts: 48021 | From Tree House | Registered: Jul 2007  |  IP: Logged | Report this post to a Moderator
Keebler
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-

here's another:

www.fda.gov/bbs/topics/NEWS/2007/NEW01638.html

FOR IMMEDIATE RELEASE_P07-90_May 23, 2007

FDA Requests Boxed Warning for Contrast Agents Used to Improve MRI Images

The U.S. Food and Drug Administration (FDA) has asked manufacturers to include a new boxed warning on the product labeling of all gadolinium-based contrast agents which are used to enhance the quality of magnetic resonance imaging (MRI).


The requested warning would state that patients with severe kidney insufficiency who receive gadolinium-based agents are at risk for developing a debilitating, and a potentially fatal disease known as nephrogenic systemic fibrosis (NSF). In addition, it would state that patients just before or just after liver transplantation, or those with chronic liver disease, are also at risk for developing NSF if they are experiencing kidney insufficiency of any severity.


"FDA has been carefully monitoring potential safety signals related to these contrast agents after receiving reports about the risk of this potentially life-threatening disease," said Steven Galson, M.D., M.P.H., director of FDA's Center for Drug Evaluation and Research. "This latest action demonstrates FDA's continuing vigilance about ensuring the safety of drug products once they enter the marketplace."


Patients with NSF develop thickening of the skin and connective tissues that inhibits their ability to move and may result in broken bones. Other organs are at risk of thickening as well. The cause of NSF is not known and there is no consistently effective treatment of this condition.

FDA first notified health care professionals and the public about the gadolinium-related risks for NSF in June 2006 . Information on the risks was updated in December.

Gadolinium-based contrast agents are commonly used to improve the visibility of internal structures when patients undergo an MRI.

Five gadolinium-based contrast agents have been approved for use in the United States: Magnevist (gadopentetate dimeglumine), Ominiscan (gadodiamide); OptiMARK (gadoversetamide); MultiHance;(gadobenate dimeglumine);and Prohance (gadoteridol).


Reports have identified the development of NSF following single and multiple administrations of the gadolinium-based contrast agents. The reports have not always identified a specific agent. Omniscan was the most commonly reported agent, when a specific agent was identified, followed by Magnevist and OptiMARK.

NSF also has developed after the sequential administration of Omniscan and MultiHance and Omniscan and ProHance. Because reports incompletely describe exposure to gadolinium-based contrast agents, it is not possible to know if the extent of risks for developing NSF is the same for all agents.

Patients should be screened for kidney problems prior to receiving one of these imaging agents. The recommended dose should not be exceeded and enough time should elapse to ensure that a dose has been eliminated from the body before the agent is used again.

There have been no reports of NSF among patients with normal kidney function or those with mild-to-moderate kidney insufficiency.

Bayer Schering Pharma, Berlin, Germany, manufactures Magnevist; GE Healthcare, Chalfont St. Giles, U.K., is the maker of Omniscan; OptiMARK is manufactured by Mallinckrodt, Inc., Hazelwood, Mo.; and ProHance and Multihance are made by Bracco Diagnostics Inc., Princeton, N.J.

For more information see www.fda.gov/cder/drug/infopage/gcca/default.htm.

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Posts: 48021 | From Tree House | Registered: Jul 2007  |  IP: Logged | Report this post to a Moderator
CaliforniaLyme
Frequent Contributor (5K+ posts)
Member # 7136

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ALCOHOL is one of the most toxic things you can possibly ingest!!!!

And actually, heroin isn't at all!!! Just to say, I'm not being prejudiced here, I don't do either one. Heroin actually preserves organs somewhat, what gets junkies is malnutrition and secondary diseases as far as effect on the body.
Heptatitis, HIV+, malnutrition can cause a whole range of terrible looking effects. But heroin does not damage organs- it almost could be called a preservative!! Heroin babies may be born addicted but their organs are usually fine.

ALCOHOL_ whoa- totally different story- HIGHLY toxic substance to the body- highly toxic- damages organs like crazy- does very bad DAMAGE to major organs if abused- and during pregnancy- FAS- Fetal Alcohol Syndrome babies are damaged for life- come out with VERY low IQ- FAS babies you can tell because their upper lips are SMOOTH- they lack that little furrow, the cleft-

I used to volunteer at this place for addict & alkie mothers with infants and boy-oh-boy- what a difference between the babies based on what the mother was using-

cocaine babies- OUCH- meth OUCH OUCH
alkie babies- OUCH
heroin babies- fine, almost all of them- was amazing- because there's this societal idea that heroin is some big bad drug and alcoholi is nothing- but alcohol is terrible, terrible to your inner organs-

including kidneys-
ESPECIALLY if you are female- I know your name is MisterGreen but if you are female you should know the female alcoholic goes down QUICKER than the male due to the way our bodies process alcohol-

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There is no wealth but life.
-John Ruskin

All truth goes through 3 stages: first it is ridiculed: then it is violently opposed: finally it is accepted as self evident. - Schopenhauer

Posts: 5639 | From Aptos CA USA | Registered: Apr 2005  |  IP: Logged | Report this post to a Moderator
   

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