LymeNet Flash: Gingko+Doxy=NoNo?

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»	LymeNet Flash » Questions and Discussion » Medical Questions » Gingko+Doxy=NoNo?

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Topic: Gingko+Doxy=NoNo?

ESG
LymeNet Contributor
Member # 4816

posted

I was re-searching Gingko here on Lymenet and found one post that said to never take Gingko with Doxy, but gave no explanation.

Does anyone have further info on this?

ESG

Posts: 424 | From Connecticut, USA | Registered: Nov 2003 | IP: Logged |

Keebler
Honored Contributor (25K+ posts)
Member # 12673

posted

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www.ncbi.nlm.nih.gov/sites/entrez

PubMed Search:

doxycycline, ginkgo - No items found.

gingko -1637 abstracts

Ginkgo biloba - 1996 abstracts

============================

www.compassionateacupuncture.com/herb%20drug_interactions.htm

HERB-DRUG INTERACTIONS AND HOW TO AVOID THEM

Conner, 2005

Excerpts:

Antibiotics (fluoroquinolones, ciprofloxacin, nitrofurantoin, TMP-SMZ antibiotics such as Bactrim, Septra, Cotrim and Sulfatrim)

v Cranberry Theoretically some antibiotics could be inhibited by the reduced urinary pH caused by cranberry. (BG)

v Fennel appears to reduce blood levels of ciprofloxacin, possibly impairing its effectiveness. (HB)

v Iron supplements may inhibit the absorption of antibiotics in the tetracycline and quinolone families. Separating intake of the iron and drugs by at least 2 hours is likely to forestall any absorption problem. (BG)

v Magnesium can interfere with absorption of antibiotics in the tetracycline and fluoroquinolones families. To avoid this problem, magnesium should be taken at least 2 hours before or after taking these drugs. (BG)

v Zinc supplements can interfere with the absorption of tetracyclines, fluoroquinolones and penicillamine. (BG)

. . .

Gingko

v Gingko interacts with aspirin and warfarin causing increased risk of bleeding by inhibiting platelet aggregation factor. (RR)

v Gingko has a blood thinning effect and therefore may be dangerous to take along with heparin (HB) and anticoagulants and antiplatelet agents. (LSR)

v Ginkgo is known to inhibit platelet activation factor and for this reason it is advisable to use caution when combining ginkgo with warfarin, heparin, aspirin or any other drugs with anticoagulant or antiplatelet effects. One case report suggests a probable interaction between ginkgo and aspirin. (BG)

v Ginkgo may increase the action of MAOIs if taken concurrently (theoretical). (LSR)

v Ginkgo may decrease the anticonvulsant effect of anticonvulsants; avoid concurrent use. (LSR)

v Ginkgo may interact with acetaminophen to increase the risk of bleeding. [xxx]

v It is conceivable that ginkgo could interact with garlic, phosphatidylserine, policosanol and vitamin E. (BG)

=======================================

www.itmonline.org/arts/herbdrug2.htm

CHECKING FOR POSSIBLE HERB-DRUG INTERACTIONS

by Subhuti Dharmananda, Ph.D., Director, Institute for Traditional Medicine, Portland, Oregon - September 2003

FULL ARTICLE AND CHARTS AT THE LINK

Excerpt:

Ginkgo may increase bleeding, especially in patients already taking certain anti-clotting medications.

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Posts: 48021 | From Tree House | Registered: Jul 2007 | IP: Logged |

Keebler
Honored Contributor (25K+ posts)
Member # 12673

posted

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http://www.ncbi.nlm.nih.gov/pubmed
PubMed Search:

ginkgo biloba, antibiotics - 23

-----------------------

Gingko was combined with an antibiotic for this test:

http://tinyurl.com/29hc4n

Zhong Yao Cai. 2002 Sep;25(9):651-3.

[Study on the antibacterial activity of ginkgolic acids]
[Article in Chinese]

Yang X, Chen J, Qian Z, Guo T.
Jiangsu University, Zhenjiang 212013.

In this article we studied the anti-bacterial activity of the extract from testa of Ginkgo biloba and ginkgolic acids.

They can inhibit the growth of Staphylocococus aureus, Escherichia coli, Bacillus subtilis, B. cereus and MRSA.

Ginkgolic acids combined with peniciline can enhance their inhibitory activity to MRSA.

PMID: 12451978 [PubMed - indexed for MEDLINE]

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Posts: 48021 | From Tree House | Registered: Jul 2007 | IP: Logged |

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