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» LymeNet Flash » Questions and Discussion » Medical Questions » please look at my western blot

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Author Topic: please look at my western blot
sunseaflower
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is there anybody to opinion about my western blot?

İgM ; 31,39,83 band positive
İgG negative

my symptoms lasts 13 years.brain fog, inability concantrate, fatigue,diffuculty thinking and speech,memory loss,

what do you think? thank you

Posts: 23 | From turkey | Registered: Dec 2004  |  IP: Logged | Report this post to a Moderator
Lymetoo
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Take that band 39 to the bank. Nothing else but Lyme can make that band show up---NOTHING. Same thing with band 83-93. I'm pretty sure band 31 is Lyme specific as well.

REad Dr C's Western Blot explanation in Medical Questions. It's the 8th "stickie" down.

I would bring part of the text here for you, but I'm on my laptop and I find it difficult to copy and paste here.

REad what he says about the bands you have.

--------------------
--Lymetutu--
Opinions, not medical advice!

Posts: 96222 | From Texas | Registered: Feb 2001  |  IP: Logged | Report this post to a Moderator
Meg
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http://flash.lymenet.org/ubb/ultimatebb.php?ubb=get_topic;f=1;t=042077

9 cross-reactive for Borrellia
12 specific for Bb
18 unknown
20 cross-reactive for Borrellia
21 unknown
22 specific for Bb, probably really the 23/25 band
23-25 outer surface protein C (OspC), specific for Bb
28 unknown
30 unknown; probably an outer surface protein; common in European and
one California strain
31 outer surface protein A (OspA), specific for Bb
34 outer surface protein B (OspB); specific for Bb
35 specific for Bb
37 specific for Bb
38 cross-reactive for Bb
39 is a major protein of Bb flagellin; specific for Bb
41 flagellin protein of all spirochetes; this is usually the first to appear after a Bb infection and is specific for all Borrellia
45 cross-reactive for all Borellia (sometimes people with Lyme who have
this band positive also have the co-infection Ehrlichiosis)
50 cross-reactive for all Borrellia
55 cross-reactive for all Borrellia
57 cross-reactive for all Borrellia
58 unknown but may be a heat-shock Bb protein
60 cross reactive for all Borrellia
66 cross-reactive for all Borrelia, common in all bacteria
83 specific antigen for the Lyme bacterium, probably a cytoplasmic membrane
93 unknown, probably the same protein in band 83, just migrates differently in some patients

--------------------
Success Stories---Treatment Guidelines

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Lymetoo
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Band 39: Unknown what this antigen is, but based on research at the National Institute of Health (NIH), other Borrelia (such as Borrelia recurrentis that causes relapsing fever), do not even have the genetics to code for the 39 kDa antigen, much less produce it. It is the most specific antibody for borreliosis of all.


Band 83: This is the DNA or genetic material of Borrelia burgdorferi. It is the same thing as the 93, based upon the medical literature. But laboratories vary in assigning significance to the 83 versus the 93.

--------------------
--Lymetutu--
Opinions, not medical advice!

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daise
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Hi sunseaflower,

13 years? Ugh.

Welcome! I see you're from Turkey. Come back with more queestions, if you like.

Hang-in there. OK?

daise [Smile]

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TS96
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Sorry your feeling so bad. I have those same symptoms.

I had + on 31, 83,93 band as well. LLMD says most definite for Lyme. The only other way you could have a positive 31 band is if you had that lyme vaccine put out awhile back. Can't remember the name.

--------------------
Bart Henslea 1976
Fibro/CFS/arthritis 2004
Lyme diagnosed 2007
3 1/2 years treatment with oral combos, Cowden, IV roc. BW herbs. Off all abx in 12/10. Feeling good.

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welcome
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quote:
Originally posted by Lymetoo:
Band 39: Unknown what this antigen is, but based on research at the National Institute of Health (NIH), other Borrelia (such as Borrelia recurrentis that causes relapsing fever), do not even have the genetics to code for the 39 kDa antigen, much less produce it. It is the most specific antibody for borreliosis of all.

For years I've challenged people on this board and others many times to show me a link or any other lead to this supposed NIH research regarding 39kDa................to no avail.

Don't get me wrong, I would love to have a verifiable copy of this "research" as I am the proud owner of this band too, however I haven't found any yet.

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sunseaflower
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thank you for all explanation. really my concerns was decreased.
i received 15 month antibiotic treatment.8 month rochephin 2 gram,3 month ketek 800mg,3 month roxitromisin. it didn t work. and it hasn t been any herxheimer reaction. one lyme sufferer said to me`, if you haven t any benefit
antibiotic treatment and you haven t been any herxheimer reaction , perhaps your diagnose may be wrong
i had western blot done 2 times and two test was positive
i have a dilemma. if i have lyme , must antibiotic provide positive effect even if its little or if i have lyme should be antibiotic cause herxheimer reaction?
my english insufficiently.i am sorry for expression fault
thank in advance

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Lymetoo
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Not everyone herxes from the antibiotics. With bands 39 and 83 present, I would say your diagnosis is right....but then I'm not a doctor!

Maybe you have some coinfections like babesia or bartonella.

--------------------
--Lymetutu--
Opinions, not medical advice!

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daise
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hi Sunseaflower,

You haven't had ANY improvement of signs or symptoms? After 15 months you should have seen improvement.

After your 13 years of misery, typically heavy duty, prolonged multiple antibiotics need to continue even beyond your 15 months of treatment.

You tested positive for Lyme.

However, have you seriously considered co-infections?

I would, if I were you! What the signs and symptoms of these are is confusing. Search this medical forum for the past 2-3 days for a thread listing signs and symptoms of a lot of co-infections.

Take care, OK?

daise

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daise
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sunseaflower
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lymetoo and daisy thanks for information

i have co enfection test done.bartonella babesia erlichiosis was negative only mycoplasma igM test was positive and i took doxy for it then igM disappeared.
i want to try rife machine as last resort.

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daise
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Hi sunseaflower,

The thread that I referred to about coinfections can be found at:
http://flash.lymenet.org/scripts/ultimatebb.cgi?ubb=get_topic;f=1;t=021366

Pleae remember that coinfections are OFTEN not diagnosable by a blood test. These are also clinical diagnoses!

The rife machine can't work for the three Lyme types of pathogens, if nothing else, because 2 of the types do not have a cell wall for the rife machine to target onto. Also, Rife is not for coinfections.

daise [Smile]

daise

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Lymetoo
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quote:
Originally posted by daise:
The rife machine can't work for the three Lyme types of pathogens, if nothing else, because 2 of the types do not have a cell wall for the rife machine to target onto. Also, Rife is not for coinfections.

I have a list of frequencies and there ARE frequencies for babesia and bartonella.

There is also a listing for "lyme hatchlings" and "lyme secondary", whatever that means.

--------------------
--Lymetutu--
Opinions, not medical advice!

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daise
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Lymetoo,

Each to their own ... that's my opinion.

daise [Smile]

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