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» LymeNet Flash » Questions and Discussion » Medical Questions » Got Igenex Results- Need Help understand

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Author Topic: Got Igenex Results- Need Help understand
xtine
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Ok. My GP didn't really make sense of it for me... this is what I got. Can someone tell me what this all means? I have no clue:

IGM- Negative
CDC- Negative

18 kDa -
22 kDa -
** 23-25 kDa ++
28 kDa -
30 kDa -
** 31 kDa IND
** 34 kDa IND
** 39 kDa -
** 41 kDa IND
45 kDa -
58 kDa +
66 kDa +
73 kDa -
** 83-93 kDa -

IGG Result- Positive
CDC- negative

18 -
22 -
** 23-25 -
28 -
30 +
** 31 ++
** 34 -
** 39 -
** 41 ++
45 -
58 -
66 -
73 -
** 83-93 -

My GP says that if the CDC says it's negative then i don't have lyme but from what i've read that can not be the case. i'm faxing over the results to my LLMD who is already treating me with abx but i don't see him for another month. he warned me that I may get IND results and that i should have waited to be tested thru IGenex but I got anxious... i should have listened to him :-)

Posts: 127 | From Toronto, Ontario Canada | Registered: Nov 2007  |  IP: Logged | Report this post to a Moderator
disturbedme
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This looks like lyme to me!!!! Stupid GP.

Stick with your LLMD.

--------------------
One can never consent to creep when one feels an impulse to soar.
~ Helen Keller

My Lyme Story

Posts: 2965 | From Land of Confusion (bitten in KS, moved to PA, now living in MD) | Registered: Jun 2007  |  IP: Logged | Report this post to a Moderator
xtine
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ya. i'm beginning to think so. yikes.
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Lymetoo
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Dr C's WB explanation:
http://flash.lymenet.org/ubb/ultimatebb.php?ubb=get_topic;f=1;t=042077

from the above link:
"The significant antibodies, in my opinion, are the 18, 23-25, 28, 30, 31, 34, 39, 58, 66 and 93."


Looks pretty much like Lyme to me too!

--------------------
--Lymetutu--
Opinions, not medical advice!

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xtine
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can i ask? is it the IGM or IGG which suggests a short term infection/long term infection?'

I belive i got infected in Aug 07 which is considered chronic but still I was hoping that it wasn't chronic according to results.

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tickled1
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Anyone can feel free to tell me if I'm wrong but I think Igg indicates past infection and Igm current infection.

Now you don't have to wonder anymore. My turn for an Igenex test!

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bettyg
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welcome to our LYME CLUB!

what lab performed your western blot igm/igg??

PRINT OFF DR. C'S FULL EXPLANATION OF W.B. testing, and circle the numbers that are POSITIVE OR IND!
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Lymetoo
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quote:
Originally posted by laura j:
Anyone can feel free to tell me if I'm wrong but I think Igg indicates past infection and Igm current infection.

Yes, with most infections, but NOT with Lyme.

xtine: Read the link!! It explains this there.

--------------------
--Lymetutu--
Opinions, not medical advice!

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xtine
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this was from Igenex...

so i have a +ve past infection but a -ve current infection? i guess the -ve current infection is +ve if you count the INDs.


does this mean that i'm getting over an infection or is it more chronic?

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xtine
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i'm reading the link but it's difficult to understand.... this article should be a lyme test :-)
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Lymetoo
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quote:
Originally posted by xtine:
[QB] this was from Igenex...

so i have a +ve past infection but a -ve current infection? i guess the -ve current infection is +ve if you count the INDs.

The opposite.

from the link:

"With most infections, your immune system first forms IgM antibodies, then in about 2 to 4 weeks, you see IgG antibodies. In some infections, IgG antibodies may be detectable for years.

Because Borrelia burgdorferi is a chronic persistent infection that may last for decades, you would think patients with chronic symptoms would have positive IgG Western blots.

But actually, more IgM blots are positive in chronic borreliosis than IgG. Every time Borrelia burgdorferi reproduces itself, it may stimulate the immune system to form new IgM antibodies.

Some patients have both IgG and IgM blots positive. But if either the IgG or IgM blot is positive, overall it is a positive result."

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--Lymetutu--
Opinions, not medical advice!

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Lymetoo
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Some have WB's contrary to what was stated above. That could be the case with you.

I wouldn't worry about it. Just treat it! [Smile]

Why don't you print out the explanation and read a little at a time. He explains it in laymen's terms.

--------------------
--Lymetutu--
Opinions, not medical advice!

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xtine
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good idea about printing it... duh, i should have thought about that. i'll do that :-)
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