posted
I took Flagyl last year without incident, but my doc just added it again as a cyst buster and, a week into it, I began having this feeling that pins were stabbing my hands (also arms, toes) REALLY HARD, then that someone was pouring fire over the places the pins just stabbed.
So I stopped the Flagyl almost 2 days ago, but the pain is getting much worse. It's really bad.
I know Flagyl can cause peripheral neuropathy. I stopped about 4-5 days after the pain started, but now I'm concerned it's not going away.
Has anyone else had peripheral neuropathy symptoms of any kind from Flagyl, and how long did they take to resolve?
Also, do any herbs or natural treatments help with this?
Posts: 929 | From Massachusetts | Registered: Oct 2007
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maybe unrelated, maybe related, i take lorazepam for akathitic sensations.
Posts: 244 | From Ottawa | Registered: Dec 2005
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minoucat
Frequent Contributor (1K+ posts)
Member # 5175
posted
The hubby had very very bad PN from flagyl. His lousy "LL" (NOT) md at the time (years ago) insisted it was a herx, so he stayed on the flagyl and the damage was pretty bad.
Mostly, it took time to resolve. It started getting better within a month, but the entire recovery lasted years.
You stopped quickly, so I think you should start feeling less PN in a couple of weeks and it should resolve completely within a few months.
B12 might help; it was suggested later for him, after the PN had already begun to resolve.
I also wonder if phosphotidyl choline might help.G And given the information below, perhaps a course of anti-inflammatories(herbs might work fine - turmeric, etc. Be worth asking a good ND)
I've also wondered if a detoxer like zeolite (Destroxin) would help -- I can't tell from what I've read if the flagyl toxins remain in the brain, slowing down recovery, or if they exit quickly but leave inflammed tissue behind.
Here's an article about what causes flagyl PN; essentially, it appears that swelling along the axons in the brain and lesions in specific areas of the brain cause the nerves to signal too intensively. This slowly reverses itself in most studies.
http://www.ajnr.org/cgi/content/full/24/8/1615 "the cause of the changes associated with acute toxic insult were most likely due to "axonal swelling with increased water content (page 89)," not demyelination."
I'd be very interested to know what helps, if you find anything that does.
-------------------- ********************* RECIDITE, PLEBES! Gero rem imperialem! (Stand aside plebians! I am on imperial business.)
posted
Thank you -- this is helpful. I was actually craving phophitidyl choline last night, so thanks for reminding me. I just took some B1 (thiamine) since it's often associated with PN and that seemed to help a little. I'm wondering if thiamine depletion from diarrhea could also be a cause (my LLMD gave me the Flagyl both as a cyst buster and on suspicion of c. diff. since I'd been having pretty severe diarrhea).
I will try these other suggestions too - thank you!
Posts: 929 | From Massachusetts | Registered: Oct 2007
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