posted
I'm reviewing my western blot from 2/28/02. I read the post on how to understand the results, but am wondering. Can someone review the results real quickly and just give me your thoughts (other than, yep you have Lyme )?
I was treated for approx 2 years with oral abx (incomplete treatment, stopped due to son needing treated too), have gone 5 years without any treatment and am now thinking that I'm having a relapse or have Bartonella (thanks to those who commented in the other post about my symptoms).
I just wanted to refresh myself on the Western Blot results so I atleast look like I know what I'm talking about when I go to the doctor.
Thanks Roxy
Posts: 31 | From PA | Registered: Apr 2008
| IP: Logged |
posted
Good grief! HIghly positive. Is this the IgG or IgM or what?
Bands 39 and 93 alone would mean you have it....but then you have a bunch of other lyme-specific bands too!
Get a bartonella test from Fry lab and see what you find.
From Dr C's WB explanation:
++++++++++++++++
The following is a brief explanation of the test results. Again, each band is an antigen complexed (bound together) with an antibody made by the immune system, specifically for that antigen (part) of Borrelia burgdorferi.
18: An outer surface protein.
22: Possibly a variant of outer surface protein C.
23-25: Outer surface protein C (osp C).
28: An outer surface protein.
30: Possibly a variant of outer surface protein A.
31: Outer surface protein A (osp A). 34: Outer surface protein B (osp B).
37: Unknown, but it is in the medical literature that it is a borrelia-associated antibody. Other labs consider it significant.
39: Unknown what this antigen is, but based on research at the National Institute of Health (NIH), other Borrelia (such as Borrelia recurrentis that causes relapsing fever), do not even have the genetics to code for the 39 kDa antigen, much less produce it. It is the most specific antibody for borreliosis of all.
41: Flagella or tail. This is how Borrelia burgdorferi moves around, by moving the flagella. Many bacteria have flagella. This is the most common borreliosis antibody.
45: Heat shock protein. This helps the bacteria survive fever. The only bacteria in the world that does not have heat shock proteins is Treponema pallidum, the cause of syphilis.
58: Heat shock protein.
66: Heat shock protein. This is the second most common borrelia antibody.
73: Heat shock protein.
83: This is the DNA or genetic material of Borrelia burgdorferi. It is the same thing as the 93, based upon the medical literature. But laboratories vary in assigning significance to the 83 versus the 93.
93: The DNA or genetic material of Borrelia burgdorferi.
In my clinical experience, if a patient has symptoms suspicious for borreliosis, and has one or more of the following bands, there is a very high probability the patient has borreliosis.
These bands are 18, 22, 23-25, 28, 30, 31, 34, 37, 39, 41, 83, and 93.
This is true regardless of whether it is IgG or IgM...
-------------------- --Lymetutu-- Opinions, not medical advice! Posts: 96239 | From Texas | Registered: Feb 2001
| IP: Logged |
Geneal
Frequent Contributor (5K+ posts)
Member # 10375
posted
Wow!
I believe it is time for you to go after it....again.
I hope your son is better.
Hugs,
Geneal
Posts: 6250 | From Louisiana | Registered: Oct 2006
| IP: Logged |
quote:Originally posted by Lymetoo: Get a bartonella test from Fry lab and see what you find.
And I was thinking, if the Bartonella comes back negative, would it be safe to assume that I'm just having a Lyme relapse? Or can you still have Bartonella without a positive test?
Sorry about all of the questions, I just forgot all of this stuff since my brain was on Lyme Overload several years ago.
Roxy
Posts: 31 | From PA | Registered: Apr 2008
| IP: Logged |
quote:Originally posted by Geneal: I hope your son is better.
Thanks so much. He's as good as he is only thru the much appreciated work of Dr. J in CT. I'm convinced my son wouldn't be as recovered as he is without him.
Almost lost everything we own just to get him treated, but it was worth it. He's almost 20 now.
Rox
Posts: 31 | From PA | Registered: Apr 2008
| IP: Logged |
The Lyme Disease Network is a non-profit organization funded by individual donations. If you would like to support the Network and the LymeNet system of Web services, please send your donations to:
The
Lyme Disease Network of New Jersey 907 Pebble Creek Court,
Pennington,
NJ08534USA http://www.lymenet.org/
UBBFriend: Email this page to someone!
![[kiss]](graemlins/kissing.gif)
)? ![[bonk]](graemlins/bonk.gif)
![[loco]](graemlins/loco.gif)
![[bow]](graemlins/bow.gif)
Printer-friendly view of this topic