posted
I am currently on 500 mg. Zithromax, 600 mg. Rifampin per day as well as Bicillin 1.2 mil/un one time per week. I am due to have my fourth shot tomorrow. About 5 days ago, I started having this "internal vibration" in the morning. Felt like I was shaking on the inside - very unnerving. I've really gotten weak on and off since starting the Zith and Rifampin (has been about 5 weeks) but the past three days have been really bad.
My legs are like jello and it's hard to lift my arms. My facial palsy on the right side is worse and my thinking is SO slow. It's hard to get words out. I've been in bed for two days now (which is hard with 4 kids).
I've never really had a bad herx thoughout 2 years of pretty low-dose treatment... Does this sound like this could be a herx? I've read about people having some pretty wicked herxes from Bicillin but I haven't felt like this before and it's really scary.
Thanks!
Shelly :-)
Posts: 292 | From UT | Registered: Aug 2001
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Can you call your doctor? If you're feeling scared I'm sure he would want to know.
You need to make sure it is a herx and not an adverse reaction.
Maybe it is a result of the combination you are taking.
These are the adverse events to watch for according to drugs.com for bicillin:
The following adverse events have been temporally associated with parenteral administration of penicillin G benzathine:
Body as a Whole: Hypersensitivity reactions including allergic vasculitis, pruritus, fatigue, asthenia, and pain; aggravation of existing disorder; headache.
Gastrointestinal: Nausea, vomiting; blood in stool; intestinal necrosis.
Hemic and Lymphatic: Lymphadenopathy.
Injection Site: Injection site reactions including pain, inflammation, lump, abscess, necrosis, edema, hemorrhage, cellulitis, hypersensitivity, atrophy, ecchymosis, and skin ulcer. Neurovascular reactions including warmth, vasospasm, pallor, mottling, gangrene, numbness of the extremities, cyanosis of the extremities, and neurovascular damage.
Metabolic: Elevated BUN, creatinine, and SGOT.
Musculoskeletal: Joint disorder; periostitis; exacerbation of arthritis; myoglobinuria; rhabdomyolysis.
Nervous System: Nervousness; tremors; dizziness; somnolence; confusion; anxiety; euphoria; transverse myelitis; seizures; coma. A syndrome manifested by a variety of CNS symptoms such as severe agitation with confusion, visual and auditory hallucinations, and a fear of impending death (Hoigne's syndrome), has been reported after administration of penicillin G procaine and, less commonly, after injection of the combination of penicillin G benzathine and penicillin G procaine.
Other symptoms associated with this syndrome, such as psychosis, seizures, dizziness, tinnitus, cyanosis, palpitations, tachycardia, and/or abnormal perception in taste, also may occur.
posted
Thanks for the info... I've looked up adverse reactions and it looks like these are temporary and immediately after administration. I placed a call to my LLMD but haven't heard back. Anyone else? Thanks!!
Posts: 292 | From UT | Registered: Aug 2001
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CD57
Frequent Contributor (1K+ posts)
Member # 11749
posted
yes. sounds familiar, I was on similar combo and had same experience. Its most likely a herx.
Posts: 3528 | From US | Registered: Apr 2007
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