posted
Hi I was wondering if any one has ever crushed up their abx's and administered using an enema??
Some one I know with Lyme had an IV and is now back on oral abx. However she is unable to keep them down. Antibiotic enema?? Anyone??
I know they do administer antibiotics with enemas but I think they are for infections in or around the colon..
Thanks for any info or help!
Posts: 22 | From St. Louis, MO. | Registered: May 2007
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Keebler
Honored Contributor (25K+ posts)
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Some medicines are used this way - but mostly as suppository for longer term absorption than a watery emema would allow. I don't know about abx, though. I would, of course, caution against any experiments.
I did ask my doctor this at one point and here is something how that discussion went:
Medicines must be able to get into the blood stream and travel throughout the body. With abx treating lyme/TBD, abx must even cross the blood brain barrier (BBB).
Foods are meant to be absorbed through the stomach and upper intestine. They are meant to be pushed through the colon. So, it's not a natural manner of absorbing for the colon, though it can happen to a degree, for certain substances.
My guess is that if an abx is irritating to the lining of the G.I. tract that it will be equally as irriating - or more so - to the lining of the colon and delicate tissues of the anal area. In additon, whatever might drain down could also be irriating to genital tissue. This would be more likely if supplied as a oil-based suppository.
So, whether particular medicines can be thoroughly absorbed throughout the colon WITHOUT causing damage to the lining of it is just the beginning of the questions. If something is added to alieviate this concern, it would need to not interfer with absorption and strength.
Also, as with some suppository treatments of other meds, the inert ingredients used in any suppository - or liquid formula - are to be considered.
I don't have the answer, just more questions and cautions.
I do know that one metal chelator, EDTA is used as a suppository. Hopefully, others with have some answers.
I've wondered if I could just do transdermal (patches) myself. So, points to consider are:
- can the amount needed get through and circulate throughout the entire body, even cross the BBB?
If so, it's good to know what the half-life will be (strength and how long the medicine would be at top strenth).
- will irriation of skin/mucous membranes be a result? (If so, that can cause serious damage).
- will other carrier agents or binders interfer with absorption or cause other effects ?
- are other carrier agents or binders, oils of the very best, organic, quality ? Are they ingredients that the body would recognize as food or foreign?
- would there be a way to do this transdermally (skin patch) and still have all the criteria met w/ minimal skin irritation?
- of utmost importance would be preventing resultant candida infections in the colon. This could result in a very serious situation, especially concerning c. diff. The flora of the colon, the pH, etc., needs a particular balance.
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