Release Date: January 17, 2008; Valid for credit through January 17, 2009
Author's Disclosures(listed off to the side where no one will likely read):
Robert I. Fox, MD, PhD Disclosure: Robert I. Fox, MD, PhD, has disclosed that he has received grants for educational activities from and served as an advisor or consultant to Allergan, Biogen/IDEC, and Genentech.
Also from the Genentech site: Novel Therapies for Unmet Medical Needs
Genentech's goal is to deliver innovative medicines to patients with serious or life-threatening medical conditions. Since its founding in 1976, the company's research organization has focused its drug discovery efforts on therapies that would fill unmet needs.
Today, Genentech manufactures and commercializes multiple biotherapeutics for critical medical conditions in the areas of oncology, immunology, and disorders of tissue growth and repair -- giving Genentech one of the leading product portfolios in the biotech industry.
From Wikipedia: Allergan, Inc., is a global specialty pharmaceutical company. Their product ranges include ophthalmic pharmaceuticals, dermatology products, and neurological products.
For almost 20 years, BOTOX� (Botulinum Toxin Type A) has been the foundation for Allergan's global leadership position in neuromodulator therapy and neurosciences.
During this time, Allergan has committed approximately $800 million in BOTOX� research and clinical development.
Today, the development of new applications for BOTOX� is continuing in new areas where unmet medical needs are greatest.
Allergan is moving forward with Phase III studies for chronic migraine, and we are continuing to conduct Phase II studies in post-stroke spasticity in the United States.
We have also initiated a clinical program for BOTOX� in the treatment of benign prostatic hypertrophy and have begun working on a next-generation BOTOX� with more selective action targeted to specific cell receptors for pain management and spasticity treatment.
Beyond BOTOX�, clinical trials are underway to investigate a unique class of alpha adrenergic agonists for neuropathic pain - an area of unmet need for non-sedating and non-addicting compounds.
Phase 3 Study: BOTOX� Chronic Migraine
Chronic Migraine
Chronic migraine is a progressive and highly disabling headache disorder characterized by headaches that occur on 15 or more days each month. It affects about 7 million Americans.1
Allergan is supporting this research because currently available preventive therapies have limitations and are widely underutilized among those who need them most.
New treatment approaches are urgently needed to lessen the burden of this serious neurological condition.
1. Castillo J, Munoz P, Guitera V, Pascual J. Epidemiology of chronic daily headache in the general population. Headache 1999. 39:190:196
Neuropathic pain is chronic pain usually accompanied by tissue injury.
Often, the nerve fibers themselves might be damaged, dysfunctional, or injured, sending incorrect signals to other pain centers.
The impact of a nerve fiber injury includes a change in nerve function both at the site of injury and areas around the injury.
Some common causes of neuropathic pain include amputation, back, leg, and hip problems, cancer chemotherapy, diabetes, facial nerve problems, multiple sclerosis, and others.
Symptoms include shooting pain, burning pain, tingling, and numbness.
Neuropathic pain often responds poorly to standard pain treatments1, which is why Allergan is supporting research in this area.
Are these disorders manifestations of chronic or untreated Lyme Disease?
Hmmmmmmm......Can YOU say "Conflict of Interest"?
[ 28. July 2008, 07:03 PM: Message edited by: AliG ]
-------------------- Note: I'm NOT a medical professional. The information I share is from my own personal research and experience. Please do not construe anything I share as medical advice, which should only be obtained from a licensed medical practitioner. Posts: 4881 | From Middlesex County, NJ | Registered: Jul 2006
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AliG
Frequent Contributor (1K+ posts)
Member # 9734
posted
If you read the CME/CE, it perpetuates the IDSA views that lead to misdiagnoses/improper treatment, thus the need to vomit.
I decided to follow the conflict trail after having read it.
Those companies stand to make a great deal of money from misdiagnosed/improperly treated Lyme Disease.
-------------------- Note: I'm NOT a medical professional. The information I share is from my own personal research and experience. Please do not construe anything I share as medical advice, which should only be obtained from a licensed medical practitioner. Posts: 4881 | From Middlesex County, NJ | Registered: Jul 2006
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AliG
Frequent Contributor (1K+ posts)
Member # 9734
posted
Did you click on this above: "Lyme Arthritis: Diagnosis and Management From a Rheumatologist's Perspective CME/CE" ?
I posted the link there.
You may have to sign up, I don't recall.
It cites "Feder et al". The part about "post-lyme syndrome", IMO really sounds like a big sissy tirade, that IDSA has become notorious for.
They think that just by repeatedly denying that active disease can exist after a pittance of treatment, they can make their nonsense true.
-------------------- Note: I'm NOT a medical professional. The information I share is from my own personal research and experience. Please do not construe anything I share as medical advice, which should only be obtained from a licensed medical practitioner. Posts: 4881 | From Middlesex County, NJ | Registered: Jul 2006
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AliG
Frequent Contributor (1K+ posts)
Member # 9734
posted
Sorry for the confusion.
I just fixed the link so it should take you right to the article now, instead of the CME page.
-------------------- Note: I'm NOT a medical professional. The information I share is from my own personal research and experience. Please do not construe anything I share as medical advice, which should only be obtained from a licensed medical practitioner. Posts: 4881 | From Middlesex County, NJ | Registered: Jul 2006
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TF
Frequent Contributor (5K+ posts)
Member # 14183
posted
Throughly disgusting! Total propaganda. It's the brainwashing of the medical profession.
It also shows that they see us as a force to be reckoned with!
Posts: 9931 | From Maryland | Registered: Dec 2007
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Michelle M
Frequent Contributor (1K+ posts)
Member # 7200
posted
That is the most fantastic assortment of lies I have ever seen in print, masquerading as a "continuing education" article.
There are so many things wrong with it I don't know where to start.
I am immediately intrigued by this part:
quote:"False positives in fibromyalgia. Concern about misdiagnosis and treatment of fibromyalgia as if it were Lyme disease led the American College of Rheumatology, in collaboration with the ISDA, to perform a cost-benefit analysis of antibiotic treatment for such patients.[1,6]
The incidence of false-positive serologic results for Lyme disease (eg, weak enzyme-linked immunosorbent assay [ELISA] results with nondiagnostic immunoblot reactivity) in patients from endemic areas with nonspecific myalgia or fatigue was 4 times that of true-positive results.[48]
Treatment of serologic false-positive patients with parenteral antibiotics costs $86,221 for each true-positive patient treated, resulting in drug toxicity in many of these patients."
First off, I don't believe it. They're claiming that fibromyalgia patients have high rates of false positive lyme tests. Yeah -- duh -- how 'bout cause they actually have lyme??
Next, they claim that can't possibly treat these 'false positives' because treatment costs approximately $86,000 per patient just for antibiotics?
Did I miss something?
Where is this so-called study about these 'false positives' -- ? I see the footnote number but no corresponding study. I want it. Fine, so I just want to mock it, but I really do want it. I've never seen this bizarre claim.
It's especially hard to believe that in this day and age of the internet and word of mouth, there exists somewhere a whole body of fibromyalgia patients who knew they had positive lyme tests but agreed to disregard them (and continue suffering) on the advice of their retarded rheumatologists.
Amazing.
Michelle
Posts: 3193 | From Northern California | Registered: Apr 2005
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Treatment of serologic false-positive patients with parenteral antibiotics costs $86,221 for each true-positive patient treated, resulting in drug toxicity in many of these patients."
OTHERWISE if you treat Lyme it could cost AN INSURANCE COMPANY $86K. Wonder where they got this number, there is only one place. From an insurance company database.
Second how does $86K, result in DRUG TOXICITY, their conclusion in the above sentence. Or do they really mean to say insurance claim toxicity.
All the more reason for early intervention and treatment.
-------------------- Positive 10 bands WB IGG & IGM + Babesia + Bartonolla and NOW RMSF 3/5/09 all at Quest
AliG
Frequent Contributor (1K+ posts)
Member # 9734
posted
YES - MY SENTIMENTS EXACTLY!!!!
(ROFLMAO)
I realize that this is really nothing to laugh at because the incredible harm that many will suffer as a result of this atrocious nonsense is truly a crime against humanity.
I still can't help but laugh because it's SO preposterous that it's almost comical. Where DID they get their information from?
I'll bet that $86K really isn't that bad compared to a lifetime of antidepressants, sleep medications, pain meds, MS treatments, and "drugs for neurological disorders, autoimmune disorders and cancer".
What happens to Gentech if all those patients start Txing with ABX and therefore have no use for those drugs in their pipeline? Do you know how much they must have laid out already, counting on a big-time return when those drugs are marketed?
How do we fix this? Who do we complain to? What studies do we need to site, to what entity to make them withdraw this CME course?
HOW CAN THEY OFFER CREDIT FOR LEARNING THIS BS PROPAGANDA?!!!!
Michele said: "retarded rheumatologists"
[ 29. July 2008, 07:38 PM: Message edited by: AliG ]
-------------------- Note: I'm NOT a medical professional. The information I share is from my own personal research and experience. Please do not construe anything I share as medical advice, which should only be obtained from a licensed medical practitioner. Posts: 4881 | From Middlesex County, NJ | Registered: Jul 2006
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