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» LymeNet Flash » Questions and Discussion » Medical Questions » Protein coating on Lyme

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Author Topic: Protein coating on Lyme
rachellemarie
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Does anyone know if the protein surrounding the lyme bacteria is lipid-coated?

I'm wondering if a product like monolaurin could be taken, which strips away this coating to expose the bacteria, so it will be easier for the antibiotic to kill it.

Has anyone happen to do any research on this?

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gemofnj
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Hi rachelle,

I went to my health food store and they gave me an enzyme which will break thu any protein coating lyme (or any bacteria can have).

It is called Virastop by Enzymedica, and I take 2 each day. She said it helps to break down the "shield" that the bacteria puts up, and then the antibiotic can do its job.

There may be others like it, but I just stumbled on this myself the other day. It seemed very interesting.

I hope it works!

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sparkle7
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Coconut oil is very good. It contains monolaurin.

I don't know too much about lipid coatings, otherwise.

The suggested dose of coconut oil is 4 tablespoons a day for theraputic dose.

Do a search for coconut oil on this website. There are alot of good posts about it.

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Hoosiers51
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4 tbsp a day? that is a LOT of fat, isn't it? Wouldn't that be like twice your daily value of fat just in coconut oil alone?
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Peedie
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I'm with sparkle - I take the extra virgin - unrefined coconut oil capsules -3 ea. day. Tried the oil which is like swallowing shortening. I couldn't handle it. The caps are easy to take.
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Pammy
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I think my Dr. gives me Artemesinin to break down the protein coating. He has me on three different things to break down each of the three layers...he described that it's like an egg. So one is to break through the "shell", one is to disrupt the "white" part and one is to destroy the dna or the way it reproduces (the yolk). I'm really bad with the technical info. (especially lately with my "lyme head") but this is an easy way for me to think about it.
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Niek
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quote:
Originally posted by rachellemarie:
Does anyone know if the protein surrounding the lyme bacteria is lipid-coated?

I'm wondering if a product like monolaurin could be taken, which strips away this coating to expose the bacteria, so it will be easier for the antibiotic to kill it.

the outer layer of the Bb spirochete is a peptidoglycan layer (protein+sugar structure), which (probably) mostly serves to evade detection by the immunesystem. So the outer layer is not lipid-coated, AFAIK. Keep in mind that there a very different forms of Bb, maybe some of them use an outer lipid layer.

As others have mentioned, virgin coconut oil contains about 50% monolaurin. I think it helps against certain yeast and bacteria, but mostly in the gut. I doubt if it can help against parasites like Bb, especially if they hide inside our cells.

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gemofnj
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I wonder why the LLMD's dont tell you this at the time you are diagnosed and give the abx for this at the time of visit.

I wasnt really aware of the coating on the bacteria. So, how do you know what kind your kind of lyme has??

Do I ask for special shield killer abx? LOL

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sparkle7
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Some further info from a website with info about HIV -

Seems it's more about being anti-viral but that's useful for us, too...

http://www.keephopealive.org/v2001.html

excerpt-

VOL. 4, NO 2 February 1, 2001

MONOLAURIN Readers report effects against various lipid viruses (HIV, HHV-6, CMV, EBV, Herpes).

Mark Konlee

Australia, Sydney: A reader, Mark C, who used Monolaurin, a modified form of lauric acid found in coconut oil, for the past 3 months reported a drop in HIV viral load form 40,000 to 7,000.

Monolaurin is sold by Ecological Formulas and is a patented product. It is sold in some health food stores and no prescription is required.

The reader also used a local botanical formula with 47 herbs in it. As both were used at the same time and were new additions to his protocol, it is an open question whether this significant drop in the viral load can be attributed solely to the Monolaurin.

He reported he used 3 capsules 2 or 3 times daily. He did not use any prescription drugs for HIV.

Another reader reported that Monolaurin got rid of his cold sores and herpes lesions. Christina White B.A, in the latest issue of New Horizons, dedicates this special issue to Multiple Sclerosis (MS). She reports that people with HHV-6 infection are getting benefits from the use of Monolaurin.

She also reports that in the central nervous system, that in one study, 73% of MS patients were infected with HHV-6.

Monolaurin has been around for over 20 years. It is a low-cost antiviral and antimicrobial and there are over a dozen patents on it filed by various researchers like Kabara, Peterson, as well as corporations like Proctor and Gamble.

Published research in a laboratory setting has found Monolaurin effective against lipid-enveloped viruses like HIV, HHV-6, CMV, EBV, herpes and others.

Other scientific studies indicates its effects against viruses that also includes influenza, helicobacter pylori, rhinoviruses, staphylococcus, strep, listeria, chlamydia, enterococcus and dental plaque (1, 2, 3,4, 6, 7)

In laboratory studies, two studies reported that a highly effective dose was 5 micrograms per ml while another study stated that 10 micrograms per ml was in inhibitory dose.

Wicker KJ et al report that at a concentration higher than 5 micrograms per ml, Monolaurin inhibited T cell proliferation and at concentrations of 0.1 micrograms/ml optimally induced proliferation of T cells (5). At higher concentrations, Monolaurin did not inhibit B cell proliferation.

Monolaurin has also been found in alcohol extracts of Saw Palmetto, a herb that is widely used for prostate infections and inflammations.

Ref: 1. J. Food Prot 2000 Nov;63(11):1503-10

2. J Med Microbiol 2000 Aug; 49(8):719-23

3. J Bacteriol 2000 May;182(9):2668-71

4. J Food Prot 1996 Mar;59(3):249-52

5. Modulation of immune cell proliferation by glycerol monolaurate, Wicker et al, Clin Diagn Lab Immunol 1996, Jan;3(1):10-3

6. Antimicrob Agents Chemother 1998 Sep;42(9):2290-4

7. J Bacteriol 1998 Jan;180(1):182-5

What is the difference between Monolaurin and Coconut oil?

The difference is that while coconut oil will act against some viruses through components like lauric acid and capric acid, Monolaurin is a modified form of lauric acid with glycerol that is significantly more effective as an anti-viral agent.

With coconut oil, some persons with HIV who have used up to 3 tablespoon daily had significant drops in viral loads, while others reported it had no effect at all. Could glycerol be the missing component? In an attempt to find out how lauric acid is modified,

I reviewed a number of patents on Monolaurin on file at the US patent office. A reading of patents gives some insights into how the product is made and the rationale for making it but not detailed information on how to make it yourself.

What I found is that various glycerol compounds and even some sugars like sucrose and fructose formed bonds with the lauric acid that modified it in a way to make it more antimicrobial and anti-viral. In patent no 4,002,775, John Kabara wrote on January 11, 1977 the following:

``In the preferred embodiment, the fatty acid is the saturated straight-chain twelve-carbon atom, lauric acid, and the polyol is glycerol. This combination exhibits activity at a level surprisingly higher than the general activity of the present esters.''
What is Glycerol?

Glycerol is Glycerin, a fatty substance that naturally exists in our body's fat cells. Glycerin is a natural component of olive oil. Pure glycerin is sold over the counter in health food stores and in pharmacies. Does this mean that I can mix olive oil or glycerin with coconut oil and get Monolaurin?

That is a good 64 dollar question. Will mixing alone create the bond or does heat have to be applied or some other process? One idea is simply to mix pure vegetable glycerin with coconut oil, such as 2 part coconut oil and one part glycerin.

However, until this mixture is tested at various dosage levels for its antimicrobial effects, we won't know how it compares to the product ``Monolaurin'' for effectiveness. We still don't know what is the optimal dosage level for using Monolaurin in treating HIV, HHV-6, CMV, EBV and other viruses.

I think that possibly an effective dosage range is from 9 to 12 capsules daily for adults, but until it is tested as a monotherapy by several persons who obtain before and after lab results, we won't know for sure.

Before we try to make up our own Monolaurin in a kitchen sink, we should use what is already manufactured under existing patents and with a demonstrated record for effectiveness.

If we can prove the efficacy of Monolaurin against HIV and other lipid enveloped viruses, we can then attempt to make a lower-cost kitchen sink version for people financially strapped here and abroad.

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rachellemarie
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I was taking monolaurin (lauric acid like in coconut oil)...I bought it here: http://www.lauricidin.com when I thought my main problem was my viral overload. Major herxing on it, I think I took too much too fast.

But then I thought, if it breaks down the coating on viruses, perhaps it could do the same for this bacteria.

Are those of you that are on other products for breaking down the walls of the bacteria finding that it is helpful? I guess it would be hard to tell for sure... [Wink]

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Niek
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quote:
Originally posted by rachellemarie:
But then I thought, if it breaks down the coating on viruses, perhaps it could do the same for this bacteria.

viruses and bacteria are biochemically VERY different; just like most antibiotics - especially anti-cellwall agents - don't work against viruses (except for an indirect effect), products like monolaurin don't work well against most bacteria.

Something that works well against both bacteria and viruses is probably also very toxic to humans ...

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GiGi
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I remember and probably took a few pounds of it over time.

http://www.lauricidin.com/about.asp

Take care.

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Marnie
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Bb has several lipoprotein "coats"/layers. They are OspA, B, C...etc.

Osp stands for outer surface proteins.

Bb uses one of OUR omega 3s in its outer cell wall to protect its *other* layers.

This omega 3 is the smallest and ***most easily oxidized*** by ROS (reactive oxygen species).

Sort of like putting on a coat which gets wet when it storms, but our street clothes underneath stay nice and dry.

This is not the first protein coat Bb picks up as a defensive measure.

As it leaves the tick, it picks up SALP15 in the tick's saliva which locks onto OUR CD4 T cells...and allows Bb time to infect...and ultimately to use its PKCD inhibitor to impact our CD3d cells so they give the wrong signal to the next cells.

Which triggers the wrong response from us.

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sparkle7
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I read somewhere that it changes these outer surface layers. Maybe like camoflage..?

I think it has different chemical things going on when we are first infected by it so it won't be detected by the immune system. Some of the immune suppression happens through the tick's saliva, too.

After that, I'm not sure what happens.

Many of us also have different viruses & co-infections. The monolaurin is probably helpful to help get rid of those. I'm not sure how it effects Lyme.

From Brian Rosner's website:

Lauricidin� is a derivative of lauric acid, a component of coconuts. The antimicrobial properties of coconut oil have long been known. Lauricidin� harnesses these properties in a concentrated formula.

Lauricidin� has also been found to have broad-spectrum antimicrobial actions against a wide range of microorganisms.

Some researchers have also speculated that Lauricidin� has a helpful effect in removing the neurotoxin associated with Lyme Disease infection, through a soap-like or emulsifying action. This effect may result in breaking up infective Lyme Disease colonies.

Lauricidin is a very promising and useful antimicrobial that has been shown, through user reports, to have a strong effect against Lyme Disease.

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