Topic: My experience w/Cumanda/Mesosilver/Enula updates
Clarissa
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Member # 4715
posted
So those of you that follow my "riveting" LLMD-declared-remission-to-reacting-to-Mesosilver story, there's now a new factor in the equation.
I decided to take Cumanda on the days I'm not taking the Mesosilver (I'm only taking Meso every 4th day (per my LLMD) because I was herxing pretty noticeably on it).
Cut to: I took 10 drops of Cumanda in the am and then 20 drops in the pm and did NOT herx and actually felt great and had extra energy.
Same thing this morning, 20 drops 5 hours ago...feel nothing. Is this a good sign?
I repeat: one teaspoon of Mesosilver= detached, depressed, tingling/numbing on whole left side/bad anxiety
30 drops of Cumanda = no herx but extra energy and some actual joyfulness, hope and laughter.
CherylSue
Frequent Contributor (1K+ posts)
Member # 13077
posted
Wow, when I first started cumanda last summer before I was diagnosed with Lyme, I herxed on 1 drop. It took me 3 months to make it to 15 drops BID. After a few more months I went to 20 drops BID.
It didn't do anything for my Lyme, but it did work on yeast I think. Not much else.
Evidently, you don't have a yeast problem.
Regarding Mesosilver, it is either toxic to your system or it is killing something. I can never tell which is which. Maybe both.
Good luck.
Hugs, CherylSue
Posts: 1954 | From Illinois | Registered: Aug 2007
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Clarissa
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posted
Thanks, CherylSue. That's the conclusion I've come too, as well (with the mesosilver).
Cumanda is also supposed to hit Bart so I'm HOPING that no herxing means a lot of my Bart is back in its cage.
A tip someone gave me from Dr. S in FL when taking Nutramedix products:
Put drops in water, then put in microwave for 1 minute. Let it sit for 1 minute, then microwave for one more minute. This reduces the alcohol level and it makes it more tolerable.
I think sometimes people are reacting to the alcohol in the product even more than the herb itself.
luvs2ride
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Member # 8090
posted
I herx strongly on silver which means to me it is working. Since it is broad spectrum (meaning hits many bacterias, fungi, parasites, etc. it could mean you have something but not necessarily lyme. Maybe yeast?)
Hubby takes it with no problem.
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Clarissa
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posted
Thanks, Luvs2ride. My LLMD thinks it's killing something as opposed to the "adverse reaction" theory.
It must be hitting something I haven't attacked or even know about. Kind of interesting but also stinks because I was supposedly on maintenance.
Oh well, better to get it NOW then have it pop up 10-years from now.
NanaDubo
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Member # 14794
posted
I'm just trying Cumanda today so I'll have to wait and see.
As far as silver goes - My LLND and my osteopath swear it's a cyst buster and that yeast etc. cannot survive in it.
I know there's lots of folks here that think it's toxic but I take it everyday.
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Clarissa
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posted
Nanadubo: Thanks for your supportive words about the silver. My LLMD also said it's a cyst buster and he's certain it's killing something based on my herx symptoms.
As I've mentioned before, he practices what he preaches and drinks 8oz daily.
How much do you take? Did you herx at first? How long have you been taking it?
Sorry for the onslaught of questions but I'd love to know as I move forward with my protocol.
posted
I would say that the reason you are reacting to Meso and not Cumanda is because Meso will hit Babs, where Cumanda is only effective against Bart. So it is a possibility that Dr S was right in telling you that you should be going after Babs according to your blood test results.
You could try a little experiment to test this theory by taking a Babs specific herb like Artemisinin or Enula to see how you react to it.
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sixgoofykids
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posted
My LLMD said that Cumanda can stimulate the immune system. He took me off it because when I take something to stimulate the immune system (like transfer factor) it makes me feel worse.
He said the immune stimulants cause cytokines and that they may be responsible for the pain I've been having.
We switched around my herbs and are leaving out the Cumanda and transfer factor.
I don't know how this applies to you, but I thought it may give you something to ponder.
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Clarissa
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posted
Thanks guys.
Micul: I thought the very same thing! Maybe the Bart is in remission and it's the untreated low pos Babs that the meso is hitting. Dr. S did want to treat but my current LLMD did not based on no clinical symptoms. Maybe this is his way of testing the waters.
I'm going to try Enula next. I do also have artemisae from Dr. Zhang in my cabinet. Which do you think would be a better "babs test?" I thought you were to only take Art with Zith and mepron. Would Art alone give me a herx if it hit the Babs?
I took 60 drops of Cumanda this am and I'm a little bit out of it...nothing like the meso, though so, yes, perhaps it's the Babs the silver it's hitting.
Tomorrow is my Meso day so that will be interesting.
Thanks SO much for all thoughtful input. I truly appreciate you taking the time.
posted
Art will work better when used in combo, but it's fine to do a little test with it for a day or two.... it can be plenty effective by itself. I would just use it since you already have some unless you're going to buy some Enula anyway.
If you burn off the alcohol in your tinctures, it will also reduce their effectiveness a little. Subjecting herbs to microwave radiation before using them is not a good thing either IMO.
-------------------- You're only a failure when you stop trying. Posts: 945 | From U.S | Registered: Oct 2004
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CherylSue
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posted
SixGoofykids, I think your doc is right on the money. I could never handle transfer factor and herxed like crazy on cumanda in the beginning. His explanation rings true in my experience.
Thanks for sharing. CherylSue
Posts: 1954 | From Illinois | Registered: Aug 2007
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CherylSue
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posted
Clarissa, you are not supposed to take 60 drops of cumanda at one time. It's 30 drops twice daily maximum. No wonder you are out of it.
I have babs symptoms and I took Enula for 3 months. It was the easiest Nutramedix herb for me to take. I had loose stools the first week or so, but that was it. I know some people herx on it. I stopped it when it didn't seem to be doing anything.
Hugs, CherylSue
Posts: 1954 | From Illinois | Registered: Aug 2007
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Marnie
Frequent Contributor (5K+ posts)
Member # 773
Mg oxide, tannic acid and then...activated charcoal.
Wanna talk more about tannic acid?
I found a LOT more links as to WHY.
For example:
Increasing evidence supports the hypothesis that tannic acid, a plant polyphenol, exerts anticarcinogenic activity in chemically induced cancers.
In the present study, tannic acid was found to strongly inhibit tyrosine kinase activity of epidermal growth factor receptor in vitro.
In contrast, the inhibition by tannic acid of p60 tyrosine kinase and insulin receptor tyrosine kinase was much weaker.
The inhibition of EGFr tyrosine kinase by tannic acid was competitive with respect to ATP and non-competitive with respect to peptide substrate.
In cultured cells, growth factor-induced tyrosine phosphorylation of growth factor receptors, including EGFr, platelet-derived growth factor receptor,
and basic fibroblast growth factor receptor, was inhibited by tannic acid.
No inhibition of insulin-induced tyrosine phosphorylation of insulin receptor and insulin-receptor substrate-1 was observed.
EGF-stimulated growth of HepG2 cells was inhibited in the presence of tannic acid.
The inhibition of serine/threonine-specific protein kinases, including cAMP-dependent protein kinase, protein kinase C and mitogen-activated protein kinase, by tannic acid was only detected at relatively high concentration, IC50 being 3, 325 and 142 microM respectively.
The molecular modeling study suggested that tannic acid could be docked into the ATP binding pockets of either EGFr or insulin receptor.
***These results demonstrate that tannic acid is an in vitro potent inhibitor of EGFr tyrosine kinase.*** PMID: 16567414
I believe Bb has a PKCd inhibitor like the drug, rettlerin. Now...
"Inhibition of PKCd using the selective inhibitor rottlerin caused a marked potentiation in 5-hydroxytryptamine secretion and the calcium response induced by alboaggregin-A stimulation of platelets, indicating that this kinase plays a negative role in the control of these processes.
In conclusion then, we have shown a physical and functional interaction between Fyn and PKCd, demonstrating a further point of
cross-talk between serine/threonine
and tyrosine kinase signaling pathways
in platelets."
Shut off/inhibit tyrosine kinase and serine/threonine is activated?
(Kinases transfer phosphate groups.)
Serine, if phosphorylated, supposedly restores the HPA axis.
Also find the relationship of tannic acid and nitrogen!
;-) Zymitol
Posts: 9481 | From Sunshine State | Registered: Mar 2001
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Clarissa
Frequent Contributor (1K+ posts)
Member # 4715
posted
Micul: I had a feeling that microwaving might make it less effective but that advice was given by Dr. S. But he also recommends much higher doses so it probably evens out in the end.
Do you think it decreases the actual HERB or just the alcohol level? After my Meso tomorrow, I will take the Cumanda at the normal dose 30 drops 2X a day but I won't microwave and see what happens. I thought it would just lessen the drunkeness feeling, not the acutal herb itself. hmmmmmmm...
When I was seeing him (Dr. S in FL), he wanted me to ramp up to 60 drops 2X a day.
CherylSue: I know it's supposed to be 30 drops 2X a day but I wanted to see what would happen if followed Dr. S's original instructions he gave me months back. I know it sounds crazy but those were his words verbatim, "ramp up to 60 drops 2X a day".
Of course, I never did because, at the time, it sounded horrifying but he's a trail blazer and hit my Bart fairly agreesively and so far, so good, "methinks" (fingers crossed)
Micul: I also have Enula in my cabinet so I'll try that SANS the microwaving when I'm done with this bottle of Cumanda.
Marnie: Thanks for all of the helpful research and the site with the marked down Nutramedix products...they can get expensive!
Thanks, again, for all of your input and I'll keep you posted.
Question: Would you just do the ONE teaspoon of Mesosilver tomorrow (that was the amount that was making me herx) or would you up it to 2 tsps or even a tablespoon?
Just curious what folks would do as it's now every 4 days instead of everyday. The goal is to be on the meso every day until symptom-free.
posted
If you need to burn off the alc because it really bothers you, then it's better to boil some water first and then place the herb in the water. But heat is not a good idea IMO because high temps can/will easily damage/change herbal properties. The alc is part of the delivery system of the tincture which makes it more effective.
"Question: Would you just do the ONE teaspoon of Mesosilver tomorrow (that was the amount that was making me herx) or would you up it to 2 tsps or even a tablespoon?"
If you're going to take Art or Enula to test tomorrow, then I wouldn't take any silver. If you will only be taking the silver tomorrow, then I would up the dose to 1 tsp tid every day at least. Then I would work up to 1 Tbl tid. I really don't see how one tsp can do much of anything as far as killing power.
I would also try using HH caps instead of Cumanda just to make sure that it's not Bart, even if you get a positive reaction from Art/Enula.
These are things that I would do if it were me. You should consult with your Dr to decide what is best for you.
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Clarissa
Frequent Contributor (1K+ posts)
Member # 4715
posted
Thanks, Micul. I really appreciate your input.
Why the heck is Dr. S telling people to do this microwave thing? Why does everything have to be controversial?
Boiling water is a much better approach. I will try with just regular "wait one minute" directions and see what happens (on Friday).
Clarissa
Frequent Contributor (1K+ posts)
Member # 4715
posted
Update:
So I took 30 drops of Cumanda last night the normal instructed way (per the bottle).
No herx.
I woke up at 6:30am and took 2 tsps of Mesosilver and went back to bed.
It's 12:15 now and my symptoms are: numb left arm and left thigh ringing in head panicky (had to take 1/2 xanax) stiff neck a little fatigued irritable, a little depressed
It's hitting something. Just can't say for sure what. I'll try the Enula tomorrow and see if I herx then maybe I'll know it's Babs.
Clarissa
Frequent Contributor (1K+ posts)
Member # 4715
posted
Friday's update:
Thursday got progressedly easier so I decided to take 2 more teaspoons of Mesosilver. Nothing major happened, just some stabbing pain in my upper left arm.
This morning took 4 drops of Enula. No herx or side effects thus far.
Sorry if this is boring anyone, just keep it on file when you have insomnia!
However, I think it's an interesting experiement to see if Mesosilver can hit things we don't even know about.
Mg oxide, tannic acid and then...activated charcoal.
Wanna talk more about tannic acid?
I found a LOT more links as to WHY.
For example:
Increasing evidence supports the hypothesis that tannic acid, a plant polyphenol, exerts anticarcinogenic activity in chemically induced cancers.
In the present study, tannic acid was found to strongly inhibit tyrosine kinase activity of epidermal growth factor receptor in vitro.
In contrast, the inhibition by tannic acid of p60 tyrosine kinase and insulin receptor tyrosine kinase was much weaker.
The inhibition of EGFr tyrosine kinase by tannic acid was competitive with respect to ATP and non-competitive with respect to peptide substrate.
In cultured cells, growth factor-induced tyrosine phosphorylation of growth factor receptors, including EGFr, platelet-derived growth factor receptor,
and basic fibroblast growth factor receptor, was inhibited by tannic acid.
No inhibition of insulin-induced tyrosine phosphorylation of insulin receptor and insulin-receptor substrate-1 was observed.
EGF-stimulated growth of HepG2 cells was inhibited in the presence of tannic acid.
The inhibition of serine/threonine-specific protein kinases, including cAMP-dependent protein kinase, protein kinase C and mitogen-activated protein kinase, by tannic acid was only detected at relatively high concentration, IC50 being 3, 325 and 142 microM respectively.
The molecular modeling study suggested that tannic acid could be docked into the ATP binding pockets of either EGFr or insulin receptor.
***These results demonstrate that tannic acid is an in vitro potent inhibitor of EGFr tyrosine kinase.*** PMID: 16567414
I believe Bb has a PKCd inhibitor like the drug, rettlerin. Now...
"Inhibition of PKCd using the selective inhibitor rottlerin caused a marked potentiation in 5-hydroxytryptamine secretion and the calcium response induced by alboaggregin-A stimulation of platelets, indicating that this kinase plays a negative role in the control of these processes.
In conclusion then, we have shown a physical and functional interaction between Fyn and PKCd, demonstrating a further point of
cross-talk between serine/threonine
and tyrosine kinase signaling pathways
in platelets."
Shut off/inhibit tyrosine kinase and serine/threonine is activated?
(Kinases transfer phosphate groups.)
Serine, if phosphorylated, supposedly restores the HPA axis.
Also find the relationship of tannic acid and nitrogen!
;-) Zymitol
Lost me YET AGAIN! Posts: 111 | From Nowhere | Registered: Jun 2008
| IP: Logged |
posted
I been taking 4 teaspoons daily of mesosilver per day.... no herx yet, no outright hell-herx anyways.
I have had some herx symptoms I believe. Headache, anxiety, some muscle pain/cramps.... my overall condition is improving without the powerful silver making me herx... what gives?
CD57
Frequent Contributor (1K+ posts)
Member # 11749
posted
Clarissa, did you see the link someone recently posted about Dr Burgdorfer having recommended mesosilver OVER ANTIBIOTICS?? Maybe your silver is hitting Lyme....? Oh it's terrible to wonder what bug this is hitting, but it sounds like it sure is hitting something. What does Dr R say about your reactions, does he offer a theory? Does HE react to the mesosilver or he's way past that?
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Clarissa
Frequent Contributor (1K+ posts)
Member # 4715
posted
Dr. R isn't sure what it's hitting but I've pretty much ruled out Bart and maybe Babs (took 14 drops of Enula today and NOTHING).
However, I could further test by taking HH for Bart or artemisae for Babs to truly know but what's the point?
It's killing something. That much Dr. R is sure of and he does NOT feel that it's a toxic or adverse reaction to the silver. He's positive it's killing based on the description of my herxes.
As far as his experience with Mesosilver, he said he never herxed at any point (but not sure if he ever had any coinfections and I think he caught his Lyme pretty early on). He just uses it as a prevention method and as an immune booster. I think he also takes Mesogold (no clue what that does but it's on www.colloidsforlife.com).
So, I'll just continue closing the gap btwn Mesosilver days and start taking daily until herxes and any remaining symptoms stop.
I guess I could take it forever but Dr. R says by no means necessary. He does it by personal choice.
luvs2ride
Frequent Contributor (1K+ posts)
Member # 8090
posted
I started Silver Shield at 1 tbsp morning and evening. Within days, my hands and wrists were hurting. Then the pain began to shoot up my arms and I was whining at work about how I did not want to have to go on disability. Finally, it dawned on me to blame the silver.
Stopped taking it and 24 hrs later, all was good again. The pain left my hands, wrists and arms.
So, I tried taking just a tsp a day. Nope. So I took a tsp every 3rd day. Yes, I could tolerate that just fine.
Like Clarissa, I started this on my own and was chicken to tell my doctor. Well, at my visit this week, darned if she didn't start me on silver. Her recommended brand Argentyn 23. She didn't have any in stock and since I had the Silver Shield, I just started it again at her dose of 10 drops daily. That is not even 1/4 tsp. I thought I would tolerate this ok but nope. After 3 doses, pain in hands and wrists. I skipped today's dose and finally the pain has receeded. I will try again at 5 drops.
There is no doubt in my mind this stuff is killing something. Not sure what, but I plan to stick with it. Kill a little and detox a lot.
-------------------- When the Power of Love overcomes the Love of Power, there will be Peace. Posts: 3038 | From america | Registered: Oct 2005
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posted
I've been having some pain in the arm/wrist and calf/ankle/left leg since I've been treating myself exclusively with silver. I wonder if it could be that its killing something
Clarissa
Frequent Contributor (1K+ posts)
Member # 4715
posted
I think it's definitely killing something in all three of us. At first, I wanted to walk away but I've come this far, so KILL KILL KILL...even if it's at a tortoise pace!
Clint: luvs2ride is right about the detoxing. You're definitely herxing which means you're killing so you want to rid your body of the die-off toxins.
Here are a few threads regarding how to detox:
posted 12 July, 2008 03:24 PM -------------------------------------------------------------------------------- Here are a bunch of threads and links that can help artciulate the importance of detoxing:
NanaDubo
Frequent Contributor (1K+ posts)
Member # 14794
posted
My LLND and my osteopath both say silver KILLS, KILLS, KILLS!
Cysts, mycoplasma, fungus, yeast, the list goes on - AND helps repair the myelin sheath.
Posts: 1129 | From Maine | Registered: Feb 2008
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Clarissa
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Member # 4715
posted
That's very encouraging!
I've never really hit cysts too agressively so that could definitely play a role in my herxes!
posted
The last few posts make me feel better about what is going on internally. Maybe the reason for the pain (the new different pain I'm having in my muscles) is it is hitting the bacteria. I have been drinking a TON of lemon water and there are some things going on that let me know I'm detoxing. (Not to be gross but I NEVER EVER have had body odor in my life and now it doesn't take much to have a little at the end of the day)
posted
Is it ok to take Mesosilver along w/ ABX? I am currently taking 500mg Ceftin BID.
Posts: 136 | From Eastern, Pa | Registered: Sep 2007
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Clarissa
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Member # 4715
posted
Clint: Gross as it may be, body odor is a GOOD sign of detoxing!
dch1112: I'm not on abx but I believe Clint is right that silver can be taken in adjunct with abx. If you want to know 100% answer, contact Mesosilver: www.colloidsforlife.com
and ask the rep. They're very helpful.
I am taking herbs with my mesosilver but spacing them out from each other.
That would be my only question, how far away to take abx from silver or can they be taken in same time-frame?
dch1112: I'm not on abx but I believe Clint is right that silver can be taken in adjunct with abx. If you want to know 100% answer, contact Mesosilver: www.colloidsforlife.com
and ask the rep. They're very helpful.
I am taking herbs with my mesosilver but spacing them out from each other.
That would be my only question, how far away to take abx from silver or can they be taken in same time-frame?
Might be a good one to post!
Best, [/QB]
thanx Clarissa... I will contact them and post their response.....
still not sure what brand to get...but according to colloidsforlife they have a chart that shows how theirs outperforms all other by miles..
dch
oh I just found this on their site after I emailed them...
"Can MesoSilver and MesoGold be taken along with prescription drugs?
Yes. MesoSilver and MesoGold do not interfere with or interact with medications. Both gold and silver are noble metals, which means they do not readily combine with other substances to form compounds, so they do not interact with medications, herbs, or other supplements."
Posts: 136 | From Eastern, Pa | Registered: Sep 2007
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posted
I said in this very thread that I was feeling as good as I've felt in a while.... just hours ago.
I picked up the overtime shift at work.... and as of now, 5:30 pm.... what's hit me since?
Dizziness when walking Headache 1 heart palpitation/skipped beat anxiety air hunger (slight) Cramping of left foot arch Twitching in left foot arch Random muscle twitches
Take it from a veteran Lymie, when you're feeling better, do NOT utter a word, much less write it anywhere.
I have jinxed myself SO many times.
Just last night, my mother and I spoke at the dinner table like this:
Me: Did you notice "someone" seems to be doing well?
Mom: Yes I did but I know we're not supposed to talk about it because we may jinx it.
Me: Mom, you have been well trained and I appreciate your discretion.
It may seem foolish but I SWEAR those buggers can hear ya bursting with joy when you feel better.
shhhhhhhhhhhhhh....
Is it just part of a herx/recovery in your opinion (for me)?
In my mind, with what I've learned about Mesosilver, I could not regress on it. It, at the very worst, would stabilize my condition. It wouldn't allow me to get worse again.
Clarissa
Frequent Contributor (1K+ posts)
Member # 4715
posted
No, you're not getting worse. The buggers are just scattering about in your body, running for their lives.
You're killing, they're dying, and sending you a last F$%& you with a die off toxin which = a herx.
The only time you MAY feel like you're getting worse is when they reproduce, which they do every 6-8 weeks (I think).
You are more vulnerable during this time and will do more killing so you will feel like it's a backslide but it is not.
Maybe you could do a separate thread inquiring about the cycles of bb and coinfections and you'll get some more solid answers. I just know that it happens!
lymebytes
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Member # 11830
posted
Isn't it funny we actually have to wonder if "feeling good" is a good sign. Well I vote yes! And have wanted to try Cumanda for a long time...I think you just convinced me.
So funny what you said, "veteran lymies know not to say when they feel good!" LOL!! SO TRUE!
Clint - I feel for you, it can change in hours. When I am lucky enough to have a whole good day, I never say anything until the day after, i.e., I had a good day yesterday. But I want to know, how can we have a good day, go to bed and wake up feeling like *&*&$%# all over again? What is it about sleep? (For me anyway...I am willing to bet a few would agree?)
TODAY, MON: 2 tsps Mesosilver AM, 1 Tablespoon Mesosilver PM, 30 drops 2X Cumanda, 15 drops 2X Enula: very mild depression, anxiety, detachment left half of body tingling/cramping slight high pitch noise in head/ears feelings of rage/no tolerance/anger burning ears/tingling on sides of face
I will be ramping up to full Enula amount (30 drops 2X daily) in the next few days.
I'll start closing the gap btwn Silver days starting next week.
Symptoms: major anxiety, some depression, no physical symptoms
SAT: 30 drops 2X Cumanda, Brought the Enula down to 20 drops 2X (I was feeling sooooo anxious and a little nauseous). No loose stools at all with Enula for me...just a teeny bit of nausea.
Symptoms: anxiety, anxiety, anxiety BUT I did shower, get dressed (mind you I had to take 1 xanax to stay calm and even) and did 3 hours of errands.
Got home, took a nap, woke up with ANXIETY, ANXIETY, ANXIETY. So much so, that I HAD togo to the gym and I rode the stationary bike for 60 minutes.
Now, if the "Lymie Urban Legend" is true, and the first horrible symptom is the LAST to go, then this is all good news because I came out of my mother's womb ANXIOUS.
SUN: Haven't taken any meds yet but it's a MESO day so hold onto your hats, guys.
Symptoms so far this am:
Left arm/shoulder/elbow/hip are a little "sore" tingly...surely a punishment for exercising MY LEGS the night before. Didn't do any exercise with arms...no weights no nothing, just cardio. SO bizarre.
And, of course, ANXIETY.
I'll update the report with a minisode tonight.
Thanks for all the inquries and I hope this input is helping others with their protocols.
Symptoms: BAD anxiety (like the kind you want to crawl out of your skin) Of course, I took xanax. crying stayed in bed for the afternoon
Physical symptoms decreased throughout the day and left side is almost back to feeling normal.
My analysis thus far: Cumanda: doing nothing but good stuff, like boosting immune system, keeping yeast in check
Enula: some stomach issues and some anxiety issues
Mesosilver: This is the big guns for me causing the darkness, scary anxiety, depression, crying, detachment and doom-like feelings.
Xanax keeps it in check and is mandatory or I'd be back at the gym peddling away for hours only to have an oxygen /blood circulation herx the next day.
NOT nearly as bad herxes as Zith & Rif combo but definitely hitting something HARD!
Next steps: This week meso once every 3 days, continue Cumanda, Enula & Burbur until it's been one month (or until I run out).
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