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» LymeNet Flash » Questions and Discussion » Medical Questions » Band 23? Also, how long do you need to be off antibiotics before taking Iginex test?

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Author Topic: Band 23? Also, how long do you need to be off antibiotics before taking Iginex test?
Pauline
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My husband tested positive for only band 23 (current infection). He has been on Doxycline based on symptoms. Does anyone know if band 23 is specific for Lyme and also how long should he be off antibiotics before retesting through Inginex? Thanks!
Posts: 144 | From Connecticut | Registered: Sep 2006  |  IP: Logged | Report this post to a Moderator
lymie tony z
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I would'nt worry too much about being off abx's any specific time...

try and schedule the draw whenever the bug is active in your hubby....

This will take some calendar watching...but if you're like a lot of folks....

flareups occur around the full moon....mine occur around the 20th of every month...

so....
and yes I believe 23 is a band in the IGM test result that shows current active infection...however I believe two are required by the CDC....

and by the way....it's igEnix....lab..you had a small typo!

zman

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I am not a doctor...opinions expressed are from personal experiences only and should never be viewed as coming from a healthcare provider. zman

Posts: 2527 | From safety harbor florida(origin Cleve., Ohio | Registered: Jan 2004  |  IP: Logged | Report this post to a Moderator
seekhelp
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I thought with Lyme you couldn't prove active vs. residual infections with IgM and IgG testing? Yes, band 23-25, 41, and one other are the key IgM bands for a CDC positive.
Posts: 7545 | From The 5th Dimension - The Twilight Zone | Registered: Mar 2008  |  IP: Logged | Report this post to a Moderator
Lymetoo
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Band 23 is very specific. I would wait two weeks after being on abx before testing.

Read this:

http://flash.lymenet.org/ubb/ultimatebb.php?ubb=get_topic;f=1;t=042077

[ 09. September 2008, 04:47 PM: Message edited by: Lymetoo ]

--------------------
--Lymetutu--
Opinions, not medical advice!

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StephenC
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quote:
Originally posted by Pauline:
My husband tested positive for only band 23 (current infection). He has been on Doxycline based on symptoms. Does anyone know if band 23 is specific for Lyme and also how long should he be off antibiotics before retesting through Inginex? Thanks!

My LLMD had me take a ten day break after taking tetracycline for ten months before drawing blood for my Igenex Lyme WB. He said the titers tend to go up during the breaks if the immune system is improving.

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Lingering chronic symptoms: Fatigue, Derealization, Brain fog. Monthly fever with flu-like symptoms that last for weeks.
Lyme WB Bands Positive: 31, 41, 58, 66
HHV6, EBV, CMV, & Mycoplasma IGG positive.
Chronically Low CD4 count.

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webmeg
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Band 23 is specific to lyme, I wouldn't ignore it even if it was the only band.

I had a conversation with my LLMD on Friday about being off abx for IGeneX testing. He said NO, stay on what you are on when getting a follow up test.

I tried to understand the technical reason and from what I could get out of it he said when you stop antibiotics the lyme calms down for a while so you can easily miss it with a Western Blot.

If you are on antibiotics you are stirring up the lyme so a Western Blot will detect it.

If you are on antibiotics and you get a clean IgeneX IgM Western Blot and are symptom free it's a good sign that you have gotten rid of it.

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Tracy9
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I was diagnosed four years ago by a well known LLD based on my WB with Band 23 alone. He said it is HIGHLY specific to Lyme and that the one band is enough for a Lyme diagnosis.

Now I have a few more bands, four years later; just had IGENEX done and am positive on 31, 41, 58, and 83-93.

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NO PM; CONTACT: [email protected]

13 years Lyme & Co.; Small Fiber Neuropathy; Myasthenia Gravis, Adrenal Insufficiency. On chemo for 2 1/2 years as experimental treatment for MG.

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Geneal
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I only had IgM band 23 also (Quest not Igenex) and it got me diagnosed

Along with 54/75 symptoms by a duck.

I had been on antibiotics for about 60 days prior to my first LLMD appt.

He felt that testing via Igenex at this time was a waste of money

Due to the time I had already been on antibiotics.

He added bartonella and babesia to my Lyme diagnosis as well.

I know that Igenex recommends "priming" the immune system

To post an antibody response with 30 days of antibiotics followed by 10-14 days off, then test.

However, you may want to call them to verify for your husband's situation.

Hugs,

Geneal

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Pauline
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Thanks everyone! That's a good idea, I think I will call igEnex.
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Lymetoo
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www.igenex.com

[hi]

--------------------
--Lymetutu--
Opinions, not medical advice!

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