Marnie
Frequent Contributor (5K+ posts)
Member # 773
posted
The Western Fence Lizard feasts on insects at night. Those insects contain formic acid (esp. ants).
Formic acid is very toxic.
``Formic acid is a mitochondrial toxin that inhibits cytochrome c oxidase, the terminal enzyme of the mitochondrial electron transport chain of all eukaryotes.''
(Animals, plants, fungi, and protists are eukaryotes organisms whose cells are organized into complex structures enclosed within membranes.)
Repeating...mitochondrial (powerhouse of the cell) cytochrome C oxidase (the last *enzyme* in the respiratory electron transport chain of mitochondria) is inhibited by formic acid.
To see a color picture of how and where cytochrome C oxidase fits in, go here and look for the small blue circle that says Cyt C in the upper right diagram:
"Zn(II) binding in Cox4 is, therefore, important for the stability of the complex."
(Bb has zinc fingers)
"Cox-4 is believed to regulate COX activity according to the extramitochondrial ATP/ADP ratio."
So, without Zn available (Bb is binding/using available zinc), it would appear COX4 could not function very well.
So how is it that the WFL destroys Bb?
The opsin of amphioxus rhodopsin can also bind 11-cis-retinal to form a photoreceptive pigment that can convert to a red-shifted photoproduct
through cis-trans isomerization of the chromophore
upon photon absorption.
The red-shifted photoproduct is
***the stable G protein activating state. ***
And opsin is a light-sensitive G protein-coupled
receptor.
Now we have a "healthy" G protein and a receptor.
The stimulatory GTP-binding protein of adenylyl cyclase(AC) regulates hormone-stimulated production of cAMP.
Here, we demonstrate that Cu2_ and Zn2_ inhibit the steady-state GTPase activity of the _subunit of GTPbinding protein (G_s) but do not alter its intrinsic GTPase activity.
Cu2_ and Zn2_ decrease steady-state GTPase activity by inhibiting the binding of GTP to G_s.
Moreover, Cu2_ and Zn2_ increase GDP dissociation from G_s and
***render the G protein in a nucleotide-free state.***
Nucleotides are organic compounds that consist of three joined structures: a nitrogenous base, a sugar, and a phosphate group.
``Homodimerization of the G protein SRβ (signal receptor beta) in the nucleotide-free state involves proline
cis/trans isomerization in the switch II region''
A homodimer is a protein made of **paired identical polypeptides** (long protein chains made of amino acids).
Let's go back to the WFL...
The opsin of amphioxus rhodopsin can also bind 11-cis-retinal to form a photoreceptive pigment that can convert to a red-shifted photoproduct
through cis-trans isomerization of the chromophore
upon photon absorption.
Did you see where "cis-trans isomerization" keeps appearing?
G proteins, short for guanine nucleotide-binding proteins, are a family of proteins involved in second messenger cascades.
G proteins are so called because they function as "molecular switches," alternating between an inactive guanosine diphosphate (GDP) and active guanosine triphosphate (GTP) bound state, ultimately going on to regulate downstream cell processes.
G proteins were discovered when Alfred G. Gilman and Martin Rodbell tried to figure out how adrenaline stimulated cells.
They found that when a hormone like adrenaline bound to a receptor, the receptor did not stimulate enzymes like adenylate cyclase directly.
Instead, the receptor stimulated a G protein, which then stimulated the adenylate cyclase to produce a second messenger, cyclic AMP.
For this discovery they won the 1994 Nobel Prize in Physiology or Medicine.
G proteins belong to the larger group of enzymes called GTPases.
Two types of DAG (Lipid mediators. Diacylglycerol (DAG) and phorbol ester) appear to be important for the physiological
activation of PKC.
One is rapidly produced from phosphatidylinositol 4,5-bisphosphate (PIP2) by phospholipase C upon
stimulation of G protein-coupled receptors.
(Bb has a PKC inhibitor.)
There is G protein again!
The G proteins ALSO interact with insulin signaling!
And...
Inhibition of PKCd reduced insulin-induced glucose uptake. (In the infected cells.)
Of course...a lot more is happening with the various nutrients...and hormones and neurotransmitters.
But the bottom line is...
it sure looks like ``photon absorption'' to activate the G proteins would be very helpful.
Finally...I found this curious (some believe autism is related to a G protein problem...as well as ongoing brain inflammation and too many adrenal steroids produced).
Anyway,
"All of the different opsins trigger a change in the membrane protein transducin, which in turn activates the enzyme phosphodiesterase, which catalyzes a molecular change that
causes sodium ion channels in the cell membrane to close.
This leads to the generation of an action potential (an impulse that will eventually reach the visual cortex in the brain)."
[ 02. November 2008, 03:07 AM: Message edited by: Marnie ]
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djf2005
Frequent Contributor (1K+ posts)
Member # 11449
posted
awesome!
more info no one knows what to do with!
(except of course for the "secret" researchers reading these posts...)
-------------------- "Experience is not what happens to you; it is what you do with what happens to you."
quote:Originally posted by Marnie: So, without Zn available (Bb is binding/using available zinc), it would appear COX4 could not function very well.
Hmmm, then do we avoid consuming Zinc so as to not provide more food for Bb, or supplement Zinc so as to boost our own supply?
Posts: 727 | From USA | Registered: Mar 2006
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(except of course for the "secret" researchers reading these posts...)
LMBO!!!!!!!
-------------------- ~*~Lyme POW~*~
I will escape. Posts: 100 | From n/a | Registered: Oct 2008
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Marnie
Frequent Contributor (5K+ posts)
Member # 773
posted
Newbies...djf2005 and hopeandhealth
I realize this is way above your heads as it has taken me 8 years and thousands of hours of research to try to understand this incredibly complex pathogen.
And copper is also involved (and copper sulfate is blue):
"Cytochrome C Oxidase, which is located in the inner mitochondrial membrane, is the terminal enzyme complex of the mitochondrial electron transport chain.
It collects electrons
that are transferred from reduced CYTOCHROME C
and donates them to molecular oxygen,
which is then reduced to water.
It is composed of CYTOCHROME A and CYTOCHROME B, ***two copper atoms***, and 13 different protein subunits, three of which are encoded by the mitochondrial DNA and ten others by nuclear DNA (mammals).
Does the photon (energy) transfer - which stimulates COX - do the following:
"By examining the gene control regions of COX4, they found that the HIF-1 (hypoxia-inducible factor 1) sensor
switched on COX4-2 activity when oxygen is low.
And they learned that because COX4-1 already is in the mitochondria,
the swap for COX4-2 occurs when the sensor turns on yet another gene that produces an enzyme to specifically chew up COX4-1.
Engineering human cells to lack this enzyme and subjecting them to low oxygen, the scientists found the cells unable to rid themselves of COX4-1."
Under normal oxygen concentrations (normoxia), COX4-1 is the predominant isoform of COX4 present in complex IV of the electron transport chain, which transfers electrons to oxygen.
During hypoxia, the absence of sufficient amounts of oxygen results in the production of reactive oxygen species (such as H2O2) that are harmful to the cell.
Fukuda et al. (2007) reveal that under hypoxic conditions, HIF-1 activates the LON protease to
degrade COX4-1 and also upregulates COX4-2 to replace COX4-1 in complex IV.
COX4-2 is more efficient at facilitating the transfer of electrons to oxygen and thereby protects the cell from oxidative damage during hypoxia.
Interestingly, forced expression of the more efficient COX4-2 under normoxic conditions results in the generation of more reactive oxygen species and an increase in caspase activity
(Fukuda et al., 2007 R. Fukuda, H. Zhang, J.-W. Kim, L. Shimoda, C.V. Dang and G.L. Semenza, Cell (2007) this issue.Fukuda et al., 2007),
which may be why COX4-2 is not the predominant isoform in complex IV."
Please note the *dates*, newbies...this is "cutting edge" stuff.
We are just BEGINNING to understand how different wavelengths of light energy can indeed heal us.
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kelmo
Frequent Contributor (1K+ posts)
Member # 8797
posted
quote: -------------------------------------------------------------------------------- Originally posted by djf2005: awesome!
more info no one knows what to do with!
(except of course for the "secret" researchers reading these posts...)
This is exactly what I think everytime something is posted and just LEFT there to try to decipher!
Posts: 2903 | From AZ | Registered: Feb 2006
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posted
Well, if you are speaking to the majority of us who just aren't as smart as you (even though I'm smart enough to not be a show off online) then why post it? I know with every post you like to mention it's above peoples' heads. It seems like you are trying to impress everyone but I think most of us just get a really good laugh. So, thanks regardless!
-------------------- ~*~Lyme POW~*~
I will escape. Posts: 100 | From n/a | Registered: Oct 2008
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seekhelp
Frequent Contributor (5K+ posts)
Member # 15067
posted
Just as all medical tests have a summary at the bottom, perhaps this would be best for the non-expert reader. Why not try to convey in three lines what the purpose of your research is and how it may help sick people like us?
Posts: 7545 | From The 5th Dimension - The Twilight Zone | Registered: Mar 2008
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posted
I remain open minded but add me to the skeptic list on this. I don't see scientific support for it.
I assume "photons" refers to packets of energy in the standard physics sense. The problem is photons generally don't penetrate far into human tissue unless they are high energy ones (think X-rays). Red/infrared photons are relatively low energy, and I don't see how they would get to where Bb is residing.
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Marnie
Frequent Contributor (5K+ posts)
Member # 773
posted
"psuedo science" ?
Let's see...
1 Active, not recruiting Far Infrared Irradiation for Control, Management and Treatment of Amyotrophic Lateral Sclerosis (ALS) Condition: Amyotrophic Lateral Sclerosis Interventions: Radiation: Far Infrared Radiation (5μm to 20μm wavelength); Radiation: Far infrared radiation
2 Recruiting Energy Specific Far Infrared Radiation Treatment for AIDS Condition: HIV Infections Interventions: Radiation: Far infrared; Radiation: Far infrared radiation
3 Active, not recruiting Far Infrared Irradiation for the Management, Control and Treatment of Frontotemporal Dementia Condition: Pick Disease of the Brain Intervention: Radiation: Radiation: Far Infrared Radiation (5μm to 20μm wavelength)
4 Active, not recruiting Far Infrared Irradiation for Stroke Rehabilitation Condition: Stroke Intervention: Radiation: Far Infrared Radiation
5 Active, not recruiting The Efficacy of Using Far Infrared Radiation to Manage Muscular Dystrophies Condition: Muscular Dystrophies Intervention: Radiation: Far Infrared Radiation
6 Active, not recruiting Far Infrared Irradiation for Management and Treating of Parkinson's Disease (PD) Condition: Parkinson's Disease Intervention: Radiation: Far Infrared Radiation (5μm to 20μm wavelength)
7 Active, not recruiting Far Infrared Radiation Treatment for Uterine Fibroids Condition: Leiomyoma Intervention: Radiation: Far Infrared Radiation (5μm to 20μm wavelength)
8 Active, not recruiting Far Infrared Irradiation for Managing, Control and Treatment of Huntington's Disease (HD) Condition: Huntington Disease Intervention: Radiation: Far Infrared Radiation
9 Active, not recruiting Far Infrared Irradiation for Managing and Treating Multiple Sclerosis (MS) Condition: Multiple Sclerosis Intervention: Radiation: Far Infrared Radiation (5μm to 20μm wavelength)
10 Active, not recruiting Far Infrared Radiation Treatment for Diabetes Condition: Diabetes Mellitus Intervention: Radiation: Far Infrared Radiation
11 Active, not recruiting Far Infrared Radiation Treatment for Prostate Cancer Condition: Prostatic Neoplasms Intervention: Radiation: Far Infrared Radiation
12 Active, not recruiting Energy Specific Far Infrared Radiation Treatment for Hyperparathyroidism Condition: Hyperparathyroidism Intervention: Radiation: Far Infrared Radiation
13 Recruiting A Study to Evaluate the Effect of Far Infrared Radiation for Cancer Treatment Condition: Neoplasms Intervention: Radiation: Far Infrared Radiation
14 Active, not recruiting Energy Specific Far Infrared Radiation Treatment for Erectile Dysfunction Condition: Erectile Dysfunction Intervention: Radiation: Far Infrared Radiation
15 Active, not recruiting Energy Specific Far Infrared Radiation Treatment for Sciatica Condition: Sciatica Intervention: Radiation: Far Infrared Radiation (5μm to 20μm wavelength)
16 Active, not recruiting Far Infrared Radiation for Sickle Cell Pain Management Condition: Anemia, Sickle Cell Intervention: Radiation: Far Infrared Radiation (5μm to 20μm wavelength)
17 Active, not recruiting Far Infrared Treatment for Alzheimer's Disease Condition: Alzheimer Disease Intervention: Radiation: Far Infrared Radiation (5μm to 20μm wavelength)
18 Active, not recruiting Far Infrared Treatment for Kidney Diseases Condition: Kidney Failure Intervention: Radiation: Far Infrared Radiation (5μm to 20μm wavelength)
19 Active, not recruiting Far Infrared Radiation Treatment for Bipolar Condition Condition: Bipolar Disorder Intervention: Radiation: Far infrared
20 Active, not recruiting Far Infrared Radiation Treatment for Osteoarthritis Condition: Osteoarthritis Intervention: Radiation: Far Infrared
21 Active, not recruiting Far Infrared Radiation Treatment of Dementia and Other Mental Illness Condition: Dementia Intervention: Radiation: Far Infrared
Given the number of "active, not recruiting" a lot of persons who are very ill are seriously participating in current gov sponsored trials using far infrared to heal.
You are making a HUGE mistake, IMO, to not consider and not try to understand HOW FAR INFRARED MIGHT INDEED WORK.
"Heme oxygenase (HO) is an enzyme that catalyzes the degradation of heme. This produces biliverdin, iron, and carbon monoxide."
(I've discussed this enzyme before on lymenet.)
HO-1 is being downregulated and far infrared "induces" HO-1:
"HO-1 induction therapy may ameliorate experimental MN via multiple pathways, including anti-oxidative, anti-apoptotic and immunomodulatory effects."
"HO-1 inducing regimens should be considered as a potential therapeutic intervention in MN in the future."
(murine membranous nephropathy)
"ELEVATED CATALASE AND HEME OXYGENASE-1 MAY CONTRIBUTE TO IMPROVED POSTISCHAEMIC CARDIAC FUNCTION IN LONG-TERM TYPE 1 DIABETES"
"HO-1 Overexpression Block Interleukin-18-Mediated NF-κB-PTEN-Dependent Human Cardiac Endothelial Cell Death"
"HO-1 overexpression, HO-1 induction, or treatment with heme metabolites all reverse IL-18-mediated p38α MAPK and NF-κB activation, PTEN induction, Akt suppression, and EC death."
"Thus, HO-1 inducers and CO donors may have the therapeutic potential to effectively block IL-18 signaling and reduce IL-18-dependent vascular injury and inflammation."
"Furthermore, HO-1 induction *suppressed* osteoclastogenesis and *bone destruction* in a TNF mediated arthritis."
"In summary, these data indicate that HO-1 negatively regulates osteoclastogenesis, leading to a positive net balance of bone."
It appears when HIF-1 goes up...HO-1 goes down.
"The mRNA expression of HO-1 and VEGF is increased under hypoxia/ischemia conditions, via the activation of an oxygen-sensing receptor,
which ultimately leads to the induction of the transcription factor hypoxia inducible factor-1 (HIF-1)"
"Contrary to our expectations, these low levels of HO-1 and VEGF in cadaveric grafts contrast to their higher hypoxic exposure, as reflected by the high expression of HIF-1a.
However, human cell lines were demonstrated recently to present
decreased expression levels of HO-1 under hypoxia,
with protein Bach-1 being implicated as a hypoxia-inducible repressor for the HO-1 gene.
In addition, a peculiar response to experimental hypoxia has been demonstrated in the kidney, which may redistribute the pre-existing VEGF protein, rather than increase mRNA and protein synthesis."
Get HO-1 up!!!
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posted
I can imagine some type of photons working. Heck, radiation treatment for cancer is photon treatment. It's the German form being talked about on this board I'm skeptical about, IMO, it's too weak, and unless it covers the whole body at the same time, my thought is Bb will just spread back into any cleared area.
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djf2005
Frequent Contributor (1K+ posts)
Member # 11449
posted
marnie-
im not a newbie nor am i uneducated.
im actually quite smart compared to most and ive been on here awhile.
what ive been saying and will continue to say is that no one can understand what you write.
i guess you dont get that as you continue to post w/o translation; but at least there are researchers who spent 8-10 yrs in school only to finally come to LN to learn about lyme
i realize you are trying to understand this pathogen and for that i thank you, but seriously, unless you are submitting this info you post then youre really wasting your time.
people who do not have a background in science have no clue what all this jargon means. its like another language. do you understand dutch, german, or french? NO! not unless you took the classes for these as you TOOK the classes in science that enable you to do this work.
long story short, and i think im out of breath from saying this so many times, TRANSLATE TRANSLATE TRANSLATE.
Comprende?
-------------------- "Experience is not what happens to you; it is what you do with what happens to you."
Marnie
Frequent Contributor (5K+ posts)
Member # 773
posted
Dates we joined Lymenet:
(You) March, 2007.
(Me) March, 2001. Number of MS word files of research = well over 3,000. I counted them about a year ago. I am NOT bragging...I'm telling you how dedicated I am to figuring out this pathogen and how to to stop it...SAFELY...and most "cost effective" for the masses infected.
My sister is now "autoimmune". She is in very bad shape. It is for her and for you all that I have continued to research for thousands and thousands of hours.
Antibiotics do NOT CURE. They HELP...a LOT!...but I am trying to find a CURE.
This is an EXTREMELY complicated pathogen.
I had a LOT to learn as I did not even know what LLMD stood for when I first joined lymenet...much less what in the heck PFK was, PKC inhibitors, SOD,catalase and glutathione, "zinc fingers", TNF alpha, IL 1 B, Th1 vs. Th2 pathway, HLA-DR, acetylcholinesterase, glutamate, serotonin conversion to melatonin, HeLa cells, Langerhans cells...the list goes on and on and on...
The worse thing about Bb, IMO, is its PKC *inhibitor*
which I am 99.99999999% sure is PKCd. Protein kinase C, delta.
That enzyme is being inhibited.
That is disasterous.
The man-made form (of the same) is the drug rottlein. It is a PKCd inhibitor.
Anytime you see that drug mentioned and the impact...think of Bb.
If you need an "appreciation" of Bb...find the Kegg pathways and enzymes this pathogen takes and uses.
That knowledge is very humbling. Know your "enemy". Then find his weakness..and outsmart him.
It CAN BE DONE.
Ancora Imparo. Translation: I am still learning. I am still "exercising" my mind.
P.S. I have no tie to any doctor, drug company, website, book, product, etc. and I never will.
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djf2005
Frequent Contributor (1K+ posts)
Member # 11449
posted
thanks for explaining why youre on your conquest.
it now makes more sense.
i can see how long youve been a member, its posted on each of your threads, as it is for everyone.
i think what youre doing is great, and if youre doing all this for "us" and your sister, it would behoove you to translate the info you discover so we can read it.
alot of people on here are very neuro and can not read what im writing here much less the technical language you consistently use.
soooo....if you would, as ive said, translate.
i know abx are not a cure. no one on here says they are. they help. they are the best weve got along with rebalancing everything else.
once you find the cure let me know.
it might also behoove you to get involved with other people gifted as you are. the ONLY way this will be beaten is by the combined effort of many.
good luck and keep it up. i am sorry to hear about your sister. unfortunately its the tenacity of this illness as you know.
derek
ps-
you have a number of novel ideas such as the use of condrosulf and the pkc inhibitor drug mentioned above but usually the threads you post in fall short of sufficiently explaining how the suggestions you make actually can work, in lay mens terms.
for example, you state above the inhibition of pkc by Bb is disastrous. ok, why?
the drug you suggest, what does it do? where do you get it? what is the mechanism on the body?
these are the relevant things i think you are missing.
congrats on the 3k MS word files, 3k more to go
-------------------- "Experience is not what happens to you; it is what you do with what happens to you."
lymie_in_md
Frequent Contributor (1K+ posts)
Member # 14197
posted
Keep up the good work Marnie!
For those, including myself, who don't understand the biochemistry completely. You have to look at this disease beyond just an ordinary infection. It has the ability to steel the enzymes our cells need to function. It does it chemically by distorting how minerals are used in the body.
When we take supplements it is the hope we are giving starved cells the nourishment they need to survive. At the same time lyme is so sophisticated an organism it can prevent our cells to communicate with each other. So the nutrients might be there but cells need intracellular communication to know the nutrients are there. 880nm does this and its provides the power to uptake nutrients.
So what is the difference between the fence lizard and us. It just might be the fence lizard is outside all day long under the sun. They just may get 30 to 40 times more daylight time then we do. Their biochemistry is built for being in sunlight. And 880nm and several other frequencies just might be the difference between us.
If someone spends hours on researching something to benefit us all. It is a little discourteous to just say I don't see the science without hours spent on their part. Just my opinion.
Hopefully Marnie is sharing just how puzzling this disease is. Is their a cure, yeah I think part if not all of it is unfolding in Germany.
-------------------- Bob Posts: 2150 | From Maryland | Registered: Dec 2007
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clairenotes
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Member # 10392
posted
It is sometimes difficult to comprehend the thinking process of a great mind. She has tripped me up many times over, but I do have to say, my compromised brain did get some exercise. Perhaps things will unfold eventually and start making more sense.
The present medical/scientific community require sound research and so there is some protection in presenting ideas within that format.
But one thing is always clear... she has great heart.
Claire
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ArtistDi
Frequent Contributor (1K+ posts)
Member # 2297
posted
Lymetoo,
I have a couple of suggestions which may help your case. These things I have been using and I believe that they are keeping things at bay for me.
I have been on IVIG for over a year now, and because of the drug assault on my immune system, I have had to break up my doses and start lower, slowing ramping the dose up. For my weight, the normal dose of IVIG is 20 grams per month. However, my hematologist broke the doses up into two. I started on only 5 grams as test dose for a few months, then 5 grams every other week. Yesterday, I did 7 grams, and hopefully if all goes well, I will do another 7 for a total of 14 grams per month.
I have read that Sjogren's can respond to IVIG. The IVIG has helped my tremors, my extremely dry skin, rebuilt muscle mass and helped with fatigue and brain fog. Definitely helps with the peripheral neuropathy. My goal is to work up to 20 grams.
I also recommend doing transdermal doxy. Even if you don't want to do orals again (and who does), you can at least keep the anti-inflammatory reactions down. I get mine at Wellness Pharmacy in Alabama. Phone # (1-800-227-2627)
Nowadays, the rheumys are using mino and doxy for R.A., and other autoimmune issues, even MS. I think this may be helpful to you. Also, the transdermal doxy is very inexpensive.
All stress exacerbates symptoms, so maybe cranial sacral could help soothe your body as well.
Unorthodox as it may seem, throughout all, I have been on low dose steroids. My LLMDS put me on this, but it must be stressed that with active infection, one can't be on them alone. They must be in tandem with antibiotics. I have been able to reduce the steroid dose to three days a week--every other day. It is possible with the reduction, that some autoimmune symptoms are creeping in. Hopefully, with the higher doses of gamma globulin, this will reset my body.
These are just some suggestions, and the things that have been helping me.
Di
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Marnie
Frequent Contributor (5K+ posts)
Member # 773
posted
What I have learned over the past 8 years based on my own research and absolutely with the help of others on this board (!!!)=
Rife works, but it takes about 2 years and the best machines are those that send the RIGHT frequencies thru an argon light (depth of penetration issue). A serious commitment to a healthy lifestyle and very specific nutrients help too.
Benicar, in high doses works. But this scares me as it can seriously damage the kidneys.
Mg pyrophosphate (= bisphosphate) and sub (lingual = under the tongue) works, but IV doses of Mg are needed. Impossible to get here. "Magnesium for autoimmune"...
(Mg inactivates HMG CoA reductase and shuts down the cholesterol pathway...which IS one of the pathways Bb takes. AND...Mg helps us to make HEALTHY antibodies to Bb's OspB. (outer surface protein).
Condroitin Sulfate in fairly high doses might work, but again...in TIME. My gut instinct is telling me this pathogen does NOT LIKE sulfate and/or iron.
Far infrared at the 880nM wavelength absolutely looks to work. This looks to increase HO-1 and halt the ongoing inflammation which is very very destructive. HO-1 is protective.
AD patients have high levels of HOS...suppresses HO-1. The body has been "tricked" into thinking a lot of free radicals will destroy Bb. They won't. This horrible pathogen is quite capable of rebuilding its cell walls that are damaged by the oxygen free radicals.
The TRPM7/ChaK1 channel has been characterized using electrophysiological techniques, and recent evidence suggests that it may play a key role in the regulation of
magnesium homeostasis.
The kinase is specific for ATP and cannot use GTP as a substrate. ChaK1-cat is insensitive to staurosporine (up to 0.1 mM) but can be
inhibited by rottlerin."
Stay with me...
Rottlerin is a man-made PKCd inhibitor! It appears Bb has a PKCd inhibitor too...which would mean Bb inhibits the KINASE function of this channel.
Now...about the WFL...
The WFL apparently has the ability to make a G protein which ultimately activates transducin which ultimately blocks the Ca-Na channel. That is what we need to happen.
This lizard via its "blue belly" looks to be able to store photons (energy) to accomplish the above.
Which is why...far infrared works.
Bb has a gene for Na-ATPase...so when Na goes in the cell, Bb shuffles it OUT...and then glucose and amino acids go in...and make Bb very happy and healthy.
I'm trying...I'm really trying hard.
I think you CAN GET WELL and I think you CAN destroy this pathogen.
I think a CURE IS POSSIBLE!
But...when the infection IS gone...there is still a LOT of "rebalancing" that must take place.
The body does not heal "overnight". Give it time.
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lymie_in_md
Frequent Contributor (1K+ posts)
Member # 14197
posted
I believe a cure is most likely found in a combination of many things.
What Dr. W. has established is the combination of nosodes and light. If you tape a nosode to the body it has the ability to signal the immune system. If 880nm is applied there is a synergy in this combination working with the body to destroy the pathogen.
The work is not over there are other issues: Co-infections, metals, detoxification, candida/fungi/yeast, chemical neurotoxins, mineral imbalances, and cellular repair, organ repair, rebuilding the flora terrain.
What I find really helps cellular and organ repair isn't 880nm but 660nm.
If you are planning to see Dr. W., it might be great idea to get a light works unit especially if you are very sick.
Just some thoughts....
-------------------- Bob Posts: 2150 | From Maryland | Registered: Dec 2007
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djf2005
Frequent Contributor (1K+ posts)
Member # 11449
posted
marnie you mention a few things which you say may be curative...
such as benicar, rife, CS, etc ect
which one in your opinion do you think holds the most promise?
thanks
derek
-------------------- "Experience is not what happens to you; it is what you do with what happens to you."
"Osteoblast proliferation was increased by all wavelengths, with the greatest increases being seen following irradiation at 830 and 880nm.
Our data demonstrate that NIR light enhances cellular proliferation, with the greatest effects being seen at 830nm. Interestingly, while proliferation was enhanced by NIR light, secretion of several important markers of osteoblast function such as osteocalcin, ALP, and TGF-β were significantly delayed, suggesting that the primary effects of the NIR irradiation were to promote cellular proliferation over differentiation. Taken together, these results suggest that NIR light may play an important role in the enhancement of fracture healing."
My sis has a LOT of bone and joint destruction going on...
Some believe MMS works, but that makes me nervous because it increases coagulation...and that is already a problem in lyme. And it increases copper levels...which brings me to...
DPen. A form of penicillin that binds zinc.
So does calprotectin in our own neutrophils.
Bb has "zinc fingers".
Yes, Doxy does also bind zinc...and a lot more metals.
I think we might need to be more "specific" as to which minerals to bind.
Iron...and zinc for starters.
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