We can also be reached by fax @ 828-252-9303 or contact us from the web.
Our Customer Service department is staffed by trained technical representatives who can assist with questions, comments, or concerns. We answer both technical and non-technical questions concerning test orders, procedures, instructions, and results.
Many of our representatives have worked in various laboratory departments and are specialized medical lab technologists. Our representatives are friendly, helpful, and outgoing, and they can support you with unique knowledge and hands-on experience.
Terry
Posts: 6286 | From Oregon | Registered: Jan 2006
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posted
I would check out Doctor's Data Lab where I had several tests for toxic metals in urine re DMPS provocation. Most naturopaths can probably do this test and two collection containers were supplied by my natpath.
A control sample taken prior to the provocation is needed and then an injection of DMPS followed by drinking copious amounts of water and collection of urine over about 6 hours in the second container.
Some info below from their website and hope this helps. web page
1. Assessment of toxic metal retention and essential element status/wasting 2.Monitors detoxification therapy 3.Analysis by ICP-MS 4.Result specific commentary provided 5.Variable urine collection periods
Urine toxic and essential elements analysis is an invaluable tool for the assessment of retention of toxic metals in the body and the status of essential nutrient elements.
Toxic metals do not have any useful physiological function, adversely affect virtually every organ system and disrupt the homeostasis of nutrient elements.
Analysis of the levels of toxic metals in urine after the administration of a metal detoxification agent is an objective way to evaluate the accumulation of toxic metals. Acute metal poisoning is rare.
More common, however, is a chronic, low-level exposure to toxic metals that can result in significant retention in the body that can be associated with a vast array of adverse health effects and not chronic disease.
Once cannot draw valid conclusions about adverse health effects of metals without assessing net retention. For an individual, toxicity occurs when net retention exceeds physiological tolerance.
Net retention is determined by the difference between the rates of assimilation and excretion of metals. To evaluate net retention, one compares the levels of metals in urine before and after the administration of a pharmaceutical metal detoxification agent such as EDTA, DMSA or DMPS.
Different compounds have different affinities for specific metals, but all function by sequestering ``hidden'' metals from deep tissue stores and mobilizing the metals to the kidneys for excretion in the urine.
Guidelines for collection periods after administration of the most commonly utilized agents are provided in the table below:
It is important to perform both pre-and post-provocation urinalysis to permit distinction between ongoing exposures to metals (pre-) and net bodily retention. The pre-provocation urine collection can also be utilized to assess the rate of creatinine clearance if a serum specimen is also submitted.
Many clinicians also request the analysis of essential elements in urine specimens to evaluate nutritional status and the efficacy of mineral supplementation during metal detoxification therapy. Metal detoxification agents can significantly increase the excretion of specific nutrient elements such as zinc, copper, manganese, and molybdenum.
Chromium metabolism authorities suggest that 24-hour chromium excretion likely provides the best assessment of chromium status. Early indication of renal dysfunction can be gleaned from urinary wasting of essential elements such as magnesium, calcium, potassium and sodium in an unprovoked specimen.
Posts: 59 | From Canada | Registered: Mar 2006
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